scholarly journals Magnetic Resonance Imaging at Ultrahigh Fields

2014 ◽  
Vol 61 (5) ◽  
pp. 1364-1379 ◽  
Author(s):  
Kamil Ugurbil
2020 ◽  
Vol 6 (3) ◽  
pp. 24-27
Author(s):  
Maíra M. Garcia ◽  
Khallil T. Chaim ◽  
Maria C. G. Otaduy ◽  
Andreas Rennings ◽  
Daniel Erni ◽  
...  

AbstractDipole radiofrequency (RF) elements have been successfully used to compose multi-channel RF coils for ultrahigh fields (UHF) magnetic resonance imaging (MRI). As magnetic components of RF fields (B1) can be very inhomogeneous at UHF (B0≥7T), dielectric pads with high dielectric constants were proposed to improve the B1 efficiency and homogeneity [1]. Dielectric pads can be used as a passive B1 shimmimg technique thanks to inducing a strong secondary magnetic field in their vicinity. The use of such dielectric pads affect not only the B1 field but also the electric field. This in turn affects the specific absorption rate (SAR) and consequently the temperature distribution inside the patient’s body. To study these effects, a 29 cm-long transmission dipole RF coil element terminated by two meander was used for 7T MRI [2]. Using a cylindrical agarose-gel phantom, numerical and experimental results were analyzed with respect to homogeneity and amplitude of the magnetic and electric fields generated by the RF element in various configurations with and without dielectric pads. Calculated and measured B1 results were cross-checked and found to be in good agreement. When using dielectric pads B1 homogeneity and magnitude increase in regions where it was previously weak or insufficient. Calculations suggest that SAR distribution will change when using the pads.


Author(s):  
Alan P. Koretsky ◽  
Afonso Costa e Silva ◽  
Yi-Jen Lin

Magnetic resonance imaging (MRI) has become established as an important imaging modality for the clinical management of disease. This is primarily due to the great tissue contrast inherent in magnetic resonance images of normal and diseased organs. Due to the wide availability of high field magnets and the ability to generate large and rapidly switched magnetic field gradients there is growing interest in applying high resolution MRI to obtain microscopic information. This symposium on MRI microscopy highlights new developments that are leading to increased resolution. The application of high resolution MRI to significant problems in developmental biology and cancer biology will illustrate the potential of these techniques.In combination with a growing interest in obtaining high resolution MRI there is also a growing interest in obtaining functional information from MRI. The great success of MRI in clinical applications is due to the inherent contrast obtained from different tissues leading to anatomical information.


1998 ◽  
Vol 41 (3) ◽  
pp. 538-548 ◽  
Author(s):  
Sean C. Huckins ◽  
Christopher W. Turner ◽  
Karen A. Doherty ◽  
Michael M. Fonte ◽  
Nikolaus M. Szeverenyi

Functional Magnetic Resonance Imaging (fMRI) holds exciting potential as a research and clinical tool for exploring the human auditory system. This noninvasive technique allows the measurement of discrete changes in cerebral cortical blood flow in response to sensory stimuli, allowing determination of precise neuroanatomical locations of the underlying brain parenchymal activity. Application of fMRI in auditory research, however, has been limited. One problem is that fMRI utilizing echo-planar imaging technology (EPI) generates intense noise that could potentially affect the results of auditory experiments. Also, issues relating to the reliability of fMRI for listeners with normal hearing need to be resolved before this technique can be used to study listeners with hearing loss. This preliminary study examines the feasibility of using fMRI in auditory research by performing a simple set of experiments to test the reliability of scanning parameters that use a high resolution and high signal-to-noise ratio unlike that presently reported in the literature. We used consonant-vowel (CV) speech stimuli to investigate whether or not we could observe reproducible and consistent changes in cortical blood flow in listeners during a single scanning session, across more than one scanning session, and in more than one listener. In addition, we wanted to determine if there were differences between CV speech and nonspeech complex stimuli across listeners. Our study shows reproducibility within and across listeners for CV speech stimuli. Results were reproducible for CV speech stimuli within fMRI scanning sessions for 5 out of 9 listeners and were reproducible for 6 out of 8 listeners across fMRI scanning sessions. Results of nonspeech complex stimuli across listeners showed activity in 4 out of 9 individuals tested.


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