On the relationship between the GLRT and UMPI tests for the detection of signals with unknown parameters

2005 ◽  
Vol 53 (11) ◽  
pp. 4194-4203 ◽  
Author(s):  
J.R. Gabriel ◽  
S.M. Kay
2012 ◽  
Vol 134 (3) ◽  
Author(s):  
Jose Manuel Luna ◽  
Ricardo Romero-Mendez ◽  
Abel Hernandez-Guerrero ◽  
Francisco Elizalde-Blancas

Based on the fact that malignant cancerous lesions (neoplasms) develop high metabolism and use more blood supply than normal tissue, infrared thermography (IR) has become a reliable clinical technique used to indicate noninvasively the presence of cancerous diseases, e.g., skin and breast cancer. However, to diagnose cancerous diseases by IR, the technique requires procedures that explore the relationship between the neoplasm characteristics (size, blood perfusion rate and heat generated) and the resulting temperature distribution on the skin surface. In this research work the dual reciprocity boundary element method (DRBEM) has been coupled with the simulated annealing technique (SA) in a new inverse procedure, which coupled to the IR technique, is capable of estimating simultaneously geometrical and thermophysical parameters of the neoplasm. The method is of an evolutionary type, requiring random initial values for the unknown parameters and no calculations of sensitivities or search directions. In addition, the DRBEM does not require any re-meshing at each proposed solution to solve the bioheat model. The inverse procedure has been tested considering input data for simulated neoplasms of different sizes and positions in relation to the skin surface. The successful estimation of unknown neoplasm parameters validates the idea of using the SA technique and the DRBEM in the estimation of parameters. Other estimation techniques, based on genetic algorithms or sensitivity coefficients, have not been capable of obtaining a solution because the skin surface temperature difference is very small.


Author(s):  
Pin-Yun Wu

The research examines the relationship between self-rated health situation and personal percep-tion of heat waves, and how social linkage of communities would be a moderator variable in residents’ perception of heat waves in Taiwan. This study uses the questionnaire conducted by Sinica “Responsive Capacity under Heat Wave: The Perspectives of the Locals”(2019), using OLS method for estimating the unknown parameters in multiple regression model. The author finds that the correlation of self-rated health situation and perception toward heat is significantly posi-tive. Also, social linkage in communities affects strongly as a moderator variable: While the sat-isfaction to with their community could reduce negative reaction to heat, contacts with neighbors could increase possibility people feel uncomfortable in high-temperature situation. This study ex-hibits the effects of social environment on community, and expects further related researches or practices to strengthen capability to resist heat wavesƒ for Taiwanese residents.


Mathematics ◽  
2020 ◽  
Vol 8 (10) ◽  
pp. 1678
Author(s):  
Jeongwook Lee ◽  
Joon Jin Song ◽  
Yongku Kim ◽  
Jung In Seo

Recently, the area of sea ice is rapidly decreasing due to global warming, and since the Arctic sea ice has a great impact on climate change, interest in this is increasing very much all over the world. In fact, the area of sea ice reached a record low in September 2012 after satellite observations began in late 1979. In addition, in early 2018, the glacier on the northern coast of Greenland began to collapse. If we are interested in record values of sea ice area, modeling relationships of these values and predicting future record values can be a very important issue because the record values that consist of larger or smaller values than the preceding observations are very closely related to each other. The relationship between the record values can be modeled based on the pivotal quantity and canonical and drawable vine copulas, and the relationship is called a dependence structure. In addition, predictions for future record values can be solved in a very concise way based on the pivotal quantity. To accomplish that, this article proposes an approach to model the dependence structure between record values based on the canonical and drawable vine. To do this, unknown parameters of a probability distribution need to be estimated first, and the pivotal-based method is provided. In the pivotal-based estimation, a new algorithm to deal with a nuisance parameter is proposed. This method allows one to reduce computational complexity when constructing exact confidence intervals of functions with unknown parameters. This method not only reduces computational complexity when constructing exact confidence intervals of functions with unknown parameters, but is also very useful for obtaining the replicated data needed to model the dependence structure based on canonical and drawable vine. In addition, prediction methods for future record values are proposed with the pivotal quantity, and we compared them with a time series forecasting method in real data analysis. The validity of the proposed methods was examined through Monte Carlo simulations and analysis for Arctic sea ice data.


2018 ◽  
Vol 17 ◽  
pp. 117693511878514
Author(s):  
Shinuk Kim

Motivation: Uncovering the relationship between micro-RNAs (miRNAs) and their target messenger RNAs (mRNAs) can provide critical information regarding the mechanisms underlying certain types of cancers. In this context, we have proposed a computational method, referred to as prediction analysis by optimization method (PAOM), to predict miRNA-mRNA relations using data from normal and cancer tissues, and then applying the relevant algorithms to colon and breast cancers. Specifically, we used 26 miRNAs and 26 mRNAs with 676 (= 26 × 26) relationships to be recovered as unknown parameters. Results: Optimization methods were used to detect 61 relationships in breast cancer and 32 relationships in colon cancer. Using sequence filtering, we detected 18 relationships in breast cancer and 15 relationships in colon cancer. Among the 18 relationships, CD24 is the target gene of let-7a and miR-98, and E2F1 is the target gene of miR-20. In addition, the frequencies of the target genes of miR-223, miR-23a, and miR-20 were significant in breast cancer, and the frequencies of the target genes of miR-17, miR-124, and miR-30a were found to be significant in colon cancer. Availability: The numerical code is available from the authors on request.


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