Intraoperative open‐lung condition and postoperative pulmonary complications. A secondary analysis of iPROVE and iPROVE‐O2 trials

2021 ◽  
Author(s):  
Carlos Ferrando ◽  
Julian Librero ◽  
Gerardo Tusman ◽  
Ary Serpa‐Neto ◽  
Jesús Villar ◽  
...  
Keyword(s):  
Secondary Analysis ◽  
Pulmonary Complications ◽  
Postoperative Pulmonary Complications ◽  
Open Lung ◽  
Lung Condition

scholarly journals The Association of Intraoperative driving pressure with postoperative pulmonary complications in open versus closed abdominal surgery patients – a posthoc propensity score–weighted cohort analysis of the LAS VEGAS study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Guido Mazzinari ◽  
◽  
Ary Serpa Neto ◽  
Sabrine N. T. Hemmes ◽  
Goran Hedenstierna ◽  
...  
Keyword(s):  
Propensity Score ◽  
Adverse Events ◽  
Abdominal Surgery ◽  
Las Vegas ◽  
Cohort Analysis ◽  
Risk Difference ◽  
Pulmonary Complications ◽  
Driving Pressure ◽  
Postoperative Pulmonary Complications ◽  
Open Abdominal Surgery

Abstract Background It is uncertain whether the association of the intraoperative driving pressure (ΔP) with postoperative pulmonary complications (PPCs) depends on the surgical approach during abdominal surgery. Our primary objective was to determine and compare the association of time–weighted average ΔP (ΔPTW) with PPCs. We also tested the association of ΔPTW with intraoperative adverse events. Methods Posthoc retrospective propensity score–weighted cohort analysis of patients undergoing open or closed abdominal surgery in the ‘Local ASsessment of Ventilatory management during General Anaesthesia for Surgery’ (LAS VEGAS) study, that included patients in 146 hospitals across 29 countries. The primary endpoint was a composite of PPCs. The secondary endpoint was a composite of intraoperative adverse events. Results The analysis included 1128 and 906 patients undergoing open or closed abdominal surgery, respectively. The PPC rate was 5%. ΔP was lower in open abdominal surgery patients, but ΔPTW was not different between groups. The association of ΔPTW with PPCs was significant in both groups and had a higher risk ratio in closed compared to open abdominal surgery patients (1.11 [95%CI 1.10 to 1.20], P <  0.001 versus 1.05 [95%CI 1.05 to 1.05], P <  0.001; risk difference 0.05 [95%CI 0.04 to 0.06], P <  0.001). The association of ΔPTW with intraoperative adverse events was also significant in both groups but had higher odds ratio in closed compared to open abdominal surgery patients (1.13 [95%CI 1.12– to 1.14], P <  0.001 versus 1.07 [95%CI 1.05 to 1.10], P <  0.001; risk difference 0.05 [95%CI 0.030.07], P <  0.001). Conclusions ΔP is associated with PPC and intraoperative adverse events in abdominal surgery, both in open and closed abdominal surgery. Trial registration LAS VEGAS was registered at clinicaltrials.gov (trial identifier NCT01601223).

Respiratory Maneuvers to Prevent Postoperative Pulmonary Complications

JAMA ◽  
1973 ◽  
Vol 224 (7) ◽  
pp. 1017 ◽  
Author(s):  
Robert H. Bartlett
Keyword(s):  
Pulmonary Complications ◽  
Postoperative Pulmonary Complications

scholarly journals STUDIES ON THE ETIOLOGY OF POSTOPERATIVE PULMONARY COMPLICATIONS

1941 ◽  
Vol 10 (6) ◽  
pp. 635-640
Author(s):  
Gustaf E. Lindskog
Keyword(s):  
Pulmonary Complications ◽  
Postoperative Pulmonary Complications

Risk factors for postoperative pulmonary complications in the treatment of non-degenerative scoliosis by posterior instrumentation and fusion

2019 ◽  
Vol 28 (6) ◽  
pp. 1356-1362 ◽  
Author(s):  
Yunsheng Wang ◽  
Yong Hai ◽  
Yuzeng Liu ◽  
Li Guan ◽  
Tie Liu
Keyword(s):  
Risk Factors ◽  
Posterior Instrumentation ◽  
Pulmonary Complications ◽  
Postoperative Pulmonary Complications ◽  
Degenerative Scoliosis
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