scholarly journals A 22-Year Follow-Up (Range 16 to 23) of Original Subjects with Baseline Alcohol Use Disorders from the Collaborative Study on Genetics of Alcoholism

2018 ◽  
Vol 42 (9) ◽  
pp. 1704-1714 ◽  
Author(s):  
Marc A. Schuckit ◽  
Tom L. Smith ◽  
George Danko ◽  
John Kramer ◽  
Kathleen K. Bucholz ◽  
...  
Keyword(s):  
Alcohol Use ◽  
Alcohol Use Disorders ◽  
Collaborative Study

scholarly journals A Prospective Comparison of Bipolar I and II Subjects With and Without Comorbid Alcohol Dependence From the COGA Dataset

2020 ◽  
Vol 11 ◽  
Author(s):  
Ulrich W. Preuss ◽  
M. N. Hesselbrock ◽  
V. M. Hesselbrock
Keyword(s):  
Bipolar Disorder ◽  
Alcohol Use ◽  
Alcohol Dependence ◽  
Collaborative Study ◽  
Structured Interviews ◽  
Prospective Comparison ◽  
Bipolar Ii ◽  
Bipolar Patients ◽  
Alcohol Dependent

Objective: Comorbidity of alcohol use disorders in bipolar subjects is high as indicated by epidemiological and clinical studies. Though a more severe course of bipolar disorder in subjects with comorbid alcohol dependence has been reported, fewer studies considered the longitudinal course of alcohol dependence in bipolar subjects and the prospective course of comorbid bipolar II subjects. Beside baseline analysis, longitudinal data of the COGA (Collaborative Study on Genetics in Alcoholism) were used to evaluate the course of bipolar I and II disordered subjects with and without comorbid alcohol dependence over more than 5 years of follow-up.Methods: Characteristics of bipolar disorder, alcohol dependence and comorbid psychiatric disorders were assessed using semi-structured interviews (SSAGA) at baseline and at a 5-year follow-up. Two hundred twenty-eight bipolar I and II patients were subdivided into groups with and without comorbid alcohol dependence.Results: Of the 152 bipolar I and 76 bipolar II patients, 172 (75, 4%) had a comorbid diagnosis of alcohol dependence. Bipolar I patients with alcohol dependence, in particular women, had a more severe course of bipolar disorder, worse social functioning and more suicidal behavior than all other groups of subjects during the 5-year follow-up. In contrast, alcohol dependence improved significantly in both comorbid bipolar I and II individuals during this time.Conclusions: A 5-year prospective evaluation of bipolar patients with and without alcohol dependence confirmed previous investigations suggesting a more severe course of bipolar disorder in comorbid bipolar I individuals, whereas bipolar II individuals were less severely impaired by comorbid alcohol use disorder. While severity of alcohol dependence improved during this time in comorbid alcohol-dependent bipolar I patients, the unfavorable outcome for these individuals might be due to the higher comorbidity with personality and other substance use disorders which, together with alcohol dependence, eventually lead to poorer symptomatic and functional clinical outcomes.

scholarly journals Sub-Clinical Anxiety and the Onset of Alcohol Use Disorders: Longitudinal Associations from the Baltimore ECA Follow-Up, 1981–2004

2010 ◽  
Vol 30 (1) ◽  
pp. 45-53 ◽  
Author(s):  
Ryan MacDonald ◽  
Rosa M. Crum ◽  
Carla L. Storr ◽  
Alyson Schuster ◽  
O. Joseph Bienvenu
Keyword(s):  
Alcohol Use ◽  
Alcohol Use Disorders ◽  
Longitudinal Associations

Cancer Incidence among Patients with Alcohol Use Disorders--Long-Term Follow-Up

2009 ◽  
Vol 44 (4) ◽  
pp. 387-391 ◽  
Author(s):  
L. C. Thygesen ◽  
P. Mikkelsen ◽  
T. V. Andersen ◽  
H. Tonnesen ◽  
K. Juel ◽  
...  
Keyword(s):  
Alcohol Use ◽  
Cancer Incidence ◽  
Alcohol Use Disorders ◽  
Long Term Follow Up

Mental Health of Protective Services Workers: Results From the National Epidemiologic Survey on Alcohol and Related Conditions

2013 ◽  
Vol 7 (1) ◽  
pp. 36-45 ◽  
Author(s):  
Christopher N. Kaufmann ◽  
Lainie Rutkow ◽  
Adam P. Spira ◽  
Ramin Mojtabai
Keyword(s):  
Mental Health ◽  
Alcohol Use ◽  
Mental Disorders ◽  
Alcohol Use Disorders ◽  
Traumatic Events ◽  
Early Career ◽  
Protective Services ◽  
Potentially Traumatic Events ◽  
Epidemiologic Survey

AbstractObjectivesTo determine the prevalence of mental disorders in a nationally representative sample of protective services workers (PSWs), compare it to that of adults in other occupations, and determine if an association exists between trauma exposure and 3-year incident psychiatric disorders in PSWs.MethodsData from the longitudinal US National Epidemiologic Survey on Alcohol and Related Conditions waves 1 (fielded 2001-2002) and 2 (fielded 2004-2005) were used to compare the prevalence of mental disorders at baseline in a representative sample of PSWs to that of adults in other occupations. Among PSWs, we also explored the association between recent exposure to potentially traumatic events and the development of mood, anxiety, and alcohol-use disorders over a 3-year follow-up period.ResultsAt baseline, PSWs had a lifetime prevalence of mental and alcohol-use disorders similar to that of adults in other occupations. However, PSWs experienced a greater variety of potentially traumatic events between baseline and follow-up. Exposure to a greater number of different trauma types was associated with increased odds of incident mood (adjusted odds ratio [AOR] = 1.87, 95% CI = 1.09-3.22, P = .024), and alcohol-use disorders (AOR = 1.84, 95% CI = 1.16-2.91, P = .011). These associations were particularly strong among early career PSWs who joined the profession between waves 1 and 2 (AOR = 2.30, 95% CI = 1.26-4.19, P = .008, for mood disorders; AOR = 2.44, 95% CI = 1.30-4.58, P = .007, for alcohol-use disorders).ConclusionsWhile PSWs do not appear to have a higher prevalence of mental health problems than workers in other occupations, they are more likely to experience multiple types of potentially traumatic events. PSWs who are exposed to multiple types of potentially traumatic events are at increased risk of developing new mental disorders, particularly in the early stages of their careers. Developing curricula in coping skills and providing timely interventions for early career PSWs may help reduce future psychiatric morbidity in these workers. (Disaster Med Public Health Preparedness. 2013;7:36-45)

Incidence and Risk of Alcohol Use Disorders by Age, Gender and Poverty Status: A Population-Based-10 Year Follow-Up Study

2017 ◽  
Vol 07 (06) ◽  
Author(s):  
Chun Te Lee ◽  
Chiu Yueh Hsiao ◽  
Yi Chyan Chen ◽  
Oswald Ndi Nfor ◽  
Jing Yang Huang ◽  
...  
Keyword(s):  
Alcohol Use ◽  
Alcohol Use Disorders ◽  
Population Based ◽  
Follow Up Study ◽  
Poverty Status

Alienation and Alcohol Use Disorder: A Thematic Analysis of Life Histories from the Lundby Study

2002 ◽  
Vol 29 (4) ◽  
pp. 779-804 ◽  
Author(s):  
Leif Öjesjö
Keyword(s):  
Alcohol Use ◽  
Life Histories ◽  
Subjective Experience ◽  
Alcohol Use Disorders ◽  
Life Course Perspective ◽  
Problem Drinkers ◽  
Treatment And Prevention ◽  
The Life Course ◽  
The Lundby Study

The 40-year follow-up of a subset of men (N=41) from the Lundby Community Cohort indicated that the development of alcohol use disorders was related to different problem areas, including work situations. The present study examines the life stories of the 23 subjects who had been interviewed 3 times before and were alive at the follow-up. It is the accounts of (mostly former) problem drinkers about how their work and their drinking fitted together. It also illuminates how work alienation is related to social class and to alcohol-use disorders and recovery. It shows that the life course perspective can lead to a fuller understanding of the subjective experience. The alienation model might also give some clues for treatment and prevention.

scholarly journals Alcohol Use Disorders Identification Test (AUDIT) and mortality risk: a systematic review and meta-analysis

2018 ◽  
Vol 72 (9) ◽  
pp. 856-863 ◽  
Author(s):  
Sören Kuitunen-Paul ◽  
Michael Roerecke
Keyword(s):  
Alcohol Use ◽  
Mortality Risk ◽  
Meta Analysis ◽  
Alcohol Use Disorders ◽  
Population Based ◽  
Moderate Drinking ◽  
Identification Test ◽  
All Cause Mortality ◽  
Meta Analyses

BackgroundWe summarise the evidence for an association between screening scores from the Alcohol Use Disorders Identification Test (AUDIT) and all-cause mortality.MethodsUsing the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, prospective cohort studies reporting all-cause mortality risk by AUDIT scores (complete AUDIT-10 or AUDIT-C) were identified through MEDLINE, Embase, PubMed and Web of Science up to September 2016. Risk estimates were pooled using random effects meta-analyses.ResultsSeven observational studies with 18 920 observed deaths among 309 991 participants were identified. At-risk drinking (ie, hazardous/harmful consumption, AUDIT-10 ≥8 and AUDIT-C ≥4) was associated with elevated mortality risk after 2–10 years of follow-up (pooled relative risk (RR)=1.24, 95% CI 1.12 to 1.37) compared with moderate drinking (AUDIT-10=1–7, AUDIT-C=1–3). Compared to past year abstainers (AUDIT=0), moderate drinkers had a lower mortality risk (RR=0.75, 95% CI 0.71 to 0.79) in US Veterans and a similar mortality risk (RR=0.99, 95% CI 0.72 to 1.38) in population-based studies. Most data came from studies among Veterans using the short AUDIT-C in men and showed a dose–response relationship (RR=1.04, 95% CI 1.04 to 1.05 for each AUDIT-C score among drinkers). Data for women and young adults were scarce.ConclusionAUDIT screening scores were associated with mortality risk. The association was differential depending on the population examined, which may be related to prevalence of former drinkers among current abstainers. Due to heterogeneity between studies and the small number of populations examined, generalisability may be limited.

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