Verrucous skin lesions on the feet in diabetic neuropathy: Successful treatment using a hollowed-out sponge

Bexarotene is a third-generation retinoid X receptor-selective retinoid that is widely used for the early treatment of advanced-stage cutaneous T-cell lymphomas. In this report, we describe a case of successful treatment of advanced primary cutaneous peripheral T-cell lymphoma not otherwise specified (PTCL-NOS) with oral bexarotene monotherapy. After the administration of oral bexarotene at a dose of 300 mg/m2/day, all skin lesions and lymph nodes regressed, and complete remission was achieved for 1 year. Our case suggested that bexarotene monotherapy could be one of the possible therapies for the treatment of primary cutaneous PTCL-NOS.

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Verrucous skin lesions on the feet in diabetic neuropathy successfully treated with topical maxacalcitol

European Journal of Dermatology ◽

10.1684/ejd.2012.1640 ◽

2012 ◽

Vol 22 (2) ◽

pp. 274-275 ◽

Cited By ~ 4

Author(s):

Kazutoshi Murao ◽

Mika Oshima ◽

Osamu Miyajima ◽

Yoshiaki Kubo

Keyword(s):

Diabetic Neuropathy ◽

Skin Lesions

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Nonhealing Wounds with Verrucous Presentation in the Neuropathic Patient: A Report of Two Cases

Journal of the American Podiatric Medical Association ◽

10.7547/17-153 ◽

2019 ◽

Vol 109 (6) ◽

pp. 471-476

Author(s):

David H. Truong ◽

Ellianne M. Nasser

Keyword(s):

Diabetic Neuropathy ◽

Current Literature ◽

Verrucous Carcinoma ◽

Foot Ulcer ◽

Skin Lesions ◽

Wide Excision ◽

Diabetic Patients ◽

Diabetic Ulcer ◽

Underlying Malignancy ◽

Neuropathic Foot

Verrucous skin lesions on the feet of diabetic patients in conjunction with a neuropathic foot ulcer is an uncommon incident. Currently, there are approximately 20 reported cases in the literature. Herein we report two cases of verrucous lesions superimposing a chronic diabetic ulcer. Patients failed several conservative treatments, and several biopsies were performed with inconclusive results, suggesting possible underlying verrucous carcinoma. Given the possibility of underlying malignancy, both patients were treated with wide excision, and both were negative for malignancy, thus confirming verrucous skin lesions on the feet in diabetic neuropathy. We also summarize the current literature on verrucous skin lesions on the feet in diabetic neuropathy.

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Successful treatment of generalized discoid skin lesions with azathioprine. Its use in a patient with systemic lupus erythematosus

Archives of Dermatology ◽

10.1001/archderm.121.10.1323 ◽

1985 ◽

Vol 121 (10) ◽

pp. 1323-1325 ◽

Cited By ~ 12

Author(s):

G. C. Tsokos

Keyword(s):

Systemic Lupus Erythematosus ◽

Successful Treatment ◽

Lupus Erythematosus ◽

Skin Lesions ◽

Systemic Lupus

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SUCCESSFUL TREATMENT OF METASTATIC SKIN LESIONS WITH ELECTROCHEMOTHERAPY

The Journal of Urology ◽

10.1097/00005392-199810000-00061 ◽

1998 ◽

pp. 1426 ◽

Cited By ~ 1

Author(s):

YOKO KUBOTA ◽

LLUIS M. MIR ◽

TERUHIRO NAKADA ◽

ISOJI SASAGAWA ◽

HITOSHI SUZUKI ◽

...

Keyword(s):

Successful Treatment ◽

Skin Lesions

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Immunohistochemical Study of Epithelioma Cuniculatum. How to differentiate it from verrucous skin lesions on the feet in diabetic neuropathy.

Nishi Nihon Hifuka ◽

10.2336/nishinihonhifu.62.503 ◽

2000 ◽

Vol 62 (4) ◽

pp. 503-507 ◽

Cited By ~ 2

Author(s):

Naoko FURUKAWA ◽

Masaki AKIYAMA ◽

Hirohiko SUEKI ◽

Ryuichi FUJISAWA ◽

Masafumi IIJIMA

Keyword(s):

Diabetic Neuropathy ◽

Immunohistochemical Study ◽

Skin Lesions ◽

Epithelioma Cuniculatum

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Topical cidofovir for benign human papillomavirus–associated skin lesions

Antiviral Therapy ◽

10.1177/13596535211059889 ◽

2021 ◽

pp. 135965352110598

Author(s):

Larry Napolitano ◽

Liesl Schroedl ◽

Alexander Kerman ◽

Christopher R Shea

Keyword(s):

Human Papillomavirus ◽

Treatment Option ◽

Successful Treatment ◽

Broad Spectrum ◽

Immune Status ◽

Response Rate ◽

Topical Therapy ◽

Case Series ◽

Antiviral Agent ◽

Skin Lesions

Cidofovir is a broad-spectrum antiviral agent that has shown efficacy against skin lesions caused by human papillomavirus (HPV). We present a case of extensive verruca vulgaris lesions refractory to imiquimod that was responsive to topical cidofovir therapy, and analyze other case series in the literature of successful treatment of benign HPV-associated skin lesions with topical cidofovir. Topical cidofovir’s favorable response rate and tolerability make it a useful treatment option for patients of differing ages and immune status who have nonmalignant HPV-associated skin lesions and desire topical therapy.

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