Analysis of the factors associated with diagnostic skin test positivity in immediate-type hypersensitivity reactions due to proton pump inhibitors

Allergy ◽  
2019 ◽  
Vol 74 (6) ◽  
pp. 1187-1190 ◽  
Author(s):  
Seçil Kepil Özdemir ◽  
Aslı Gelincik ◽  
Nail Paksoy ◽  
Gözde Köycü Buhari ◽  
Ferda Öner Erkekol ◽  
...  
Keyword(s):  
Skin Test ◽  
Proton Pump Inhibitors ◽  
Proton Pump ◽  
Hypersensitivity Reactions ◽  
Factors Associated

Hypersensitivity reactions to proton-pump inhibitors: Clinical presentation, diagnosis, and management

2020 ◽  
Vol 41 (2) ◽  
pp. e37-e44 ◽  
Author(s):  
Seçil Kepil Özdemir ◽  
Sevim Bavbek
Keyword(s):  
Proton Pump Inhibitors ◽  
Proton Pump ◽  
Clinical Presentation ◽  
Current Knowledge ◽  
Cross Reactivity ◽  
Delayed Hypersensitivity ◽  
Stevens Johnson Syndrome ◽  
Hypersensitivity Reactions ◽  
Fixed Drug Eruption ◽  
Maculopapular Eruption

Background: Proton-pump inhibitors (PPI) are one of the most commonly prescribed drugs, and they are generally well tolerated. However, several immediate and delayed hypersensitivity reactions due to PPIs have been reported. Objective: To review the clinical characteristics and management of immune-mediated immediate and delayed hypersensitivity reactions to PPIs. Methods: We performed a search of a medical literature data base from January 1980 to October 2019 by using keywords that included “proton-pump inhibitors” and “hypersensitivity.” Results: Anaphylaxis is the most-common clinical presentation in patients with immediate hypersensitivity reactions to PPIs, followed by urticaria and/or angioedema. Occupational contact dermatitis, maculopapular eruption, fixed drug eruption, symmetrical drug-related intertriginous and flexural exanthema, and severe cutaneous adverse reactions, such as Stevens-Johnson syndrome, toxic epidermal necrolysis, drug rash with eosinophilia and systemic symptoms, and acute generalized exanthematous pustulosis have also been reported with PPIs. Conclusion: The current knowledge and severity of the reported reactions indicated the importance of consideration of a causal relationship between hypersensitivity reactions and PPIs, and awareness of the existence of cross-reactivity among PPIs.

scholarly journals Factors associated with the initiation of proton pump inhibitors in corticosteroid users

2012 ◽  
Vol 21 (4) ◽  
pp. 366-374 ◽  
Author(s):  
Jeffrey C. Munson ◽  
Peter M. Wahl ◽  
Gregory Daniel ◽  
Stephen E. Kimmel ◽  
Sean Hennessy
Keyword(s):  
Proton Pump Inhibitors ◽  
Proton Pump ◽  
Factors Associated

Immediate-type hypersensitivity reactions to proton pump inhibitors: usefulness of skin tests in the diagnosis and assessment of cross-reactivity

Allergy ◽  
2013 ◽  
Vol 68 (8) ◽  
pp. 1008-1014 ◽  
Author(s):  
S. Kepil Özdemir ◽  
İ. Yılmaz ◽  
Ö. Aydın ◽  
S. Büyüköztürk ◽  
A. Gelincik ◽  
...  
Keyword(s):  
Proton Pump Inhibitors ◽  
Proton Pump ◽  
Cross Reactivity ◽  
Skin Tests ◽  
Hypersensitivity Reactions

Delayed-type hypersensitivity reactions induced by proton pump inhibitors: A clinical and in vitro T-cell reactivity study

Allergy ◽  
2017 ◽  
Vol 73 (1) ◽  
pp. 221-229 ◽  
Author(s):  
C.-y. Lin ◽  
C.-W. Wang ◽  
C.-Y. R. Hui ◽  
Y.-C. Chang ◽  
C.-H. Yang ◽  
...  
Keyword(s):  
T Cell ◽  
Proton Pump Inhibitors ◽  
Proton Pump ◽  
Delayed Type Hypersensitivity ◽  
Hypersensitivity Reactions ◽  
Cell Reactivity ◽  
T Cell Reactivity ◽  
Reactivity Study

scholarly journals Meta-analysis used to identify factors associated with the effectiveness of proton pump inhibitors against non-erosive reflux disease

2009 ◽  
Vol 24 (8) ◽  
pp. 1326-1332 ◽  
Author(s):  
Toru Hiyama ◽  
Keitaro Matsuo ◽  
Yuji Urabe ◽  
Tatsuma Fukuhara ◽  
Shinji Tanaka ◽  
...  
Keyword(s):  
Proton Pump Inhibitors ◽  
Proton Pump ◽  
Reflux Disease ◽  
Meta Analysis ◽  
Factors Associated

Skin Test Predictive Value On The Proton Pump Inhibitors Allergy

2011 ◽  
Vol 127 (2) ◽  
pp. AB188-AB188
Author(s):  
P. Bonadonna ◽  
M. Pagani ◽  
A. Bircher ◽  
K. Scherer ◽  
B. Caruso ◽  
...  
Keyword(s):  
Skin Test ◽  
Proton Pump Inhibitors ◽  
Proton Pump ◽  
Predictive Value
Sign in / Sign up

Export Citation Format

Share Document