Rare cases of hidradenitis suppurativa (Verneuil's disease) of perineum and perianal region

2018 ◽  
Vol 89 (9) ◽  
pp. 1169-1170
Author(s):  
Min Hoe Chew ◽  
Mutee U. Rehman ◽  
Amanda See
Keyword(s):  
Hidradenitis Suppurativa ◽  
Perianal Region ◽  
Verneuil’S Disease

Squamous-cell cancer in Verneuil's disease (hidradenitis suppurativa)

The Lancet ◽  
1996 ◽  
Vol 348 (9039) ◽  
pp. 1449 ◽  
Author(s):  
Mariano Malaguarnera ◽  
Tindaro Pontillo ◽  
Giovanni Pistone ◽  
Lino Succi
Keyword(s):  
Squamous Cell ◽  
Hidradenitis Suppurativa ◽  
Squamous Cell Cancer ◽  
Cell Cancer ◽  
Verneuil’S Disease

scholarly journals Verneuil’s Disease or Hidradenitis Suppurativa Complicated by Verrucous Carcinoma: Description of a Case with Extremely Extended Pathology in Pregnancy

2020 ◽  
pp. 1-4
Author(s):  
Domenico Parmeggiani ◽  
Domenico Parmeggiani ◽  
Roberto Ruggiero ◽  
Giuseppe Chiacchio ◽  
Franco Faccenda ◽  
...  
Keyword(s):  
Hidradenitis Suppurativa ◽  
Verrucous Carcinoma ◽  
Maximum Diameter ◽  
Excision Biopsy ◽  
Milk Analysis ◽  
Hormonal Activity ◽  
Sinus Pilonidalis ◽  
Apocrine Glands ◽  
Verneuil’S Disease ◽  
In Pregnancy

Background: Verneuil’s disease is a rare suppurative pathology of apocrine glands and pilosebaceous system of the inguinal-pelvis and perianal region with a multifactorial aetiology. The disease produces skin fistulas, draining a serum-purulent material on the skin, and finally with spontaneous healing. Verneuil’s disease can be complicated by recurrence, and unfortunately, by squamous carcinoma. We have found in literature, just 2 cases of Hidradenitis Suppurativa, complicated by Verrucous Carcinoma. Main Observation: we describe a patient F, 34-year-old, comes to our observation at 4th gestational month, with suppurative sinus pilonidalis diagnosis and with the absolute indication of the gynaecologist to the abortion. We decided to continue the pregnancy. The patient gives birth with C. to 9 months; the new-born baby was perfectly healthy and after the maternal milk analysis, the baby also nursed for about 2 months. Finally, we decided to perform a wide excision biopsy and after a controversial histology (first Warty Carcinoma, then after a “second view” Suppurative Hidradenitis), we started a series of medical treatments, including biological therapy with Infliximab, but unfortunately with fleeting results. The patient did not answer substantially. Therefore, the last chance appears a combined demolitive and plastic surgical treatment. The histology described a Verrucous squamous cell carcinoma maximum diameter of 38 x 26 cm, with lateral deep margins free of neoplastic involvement. Conclusion: This very advanced clinical behaviour of the Hidradenitis Suppurativa can present in pregnancy, therefore, motivating the interruption of the same one. Our experience contributes to underlining the possibility to bring to term the pregnancy. This case report shows how the hormonal activity can anyway influence the development of the hidradenitis and an interesting hypothesis could consider the hormonal activity of the pregnancy and the HPV promoting gene regulation (RB) from inflammatory pathology to neoplastic pathology in VC like a model to study.

scholarly journals Miscellaneous Perianal Afflictions

2019 ◽  
Vol 32 (05) ◽  
pp. 394-402
Author(s):  
Gonzalo F. Hagerman ◽  
Jorge Silva-Velazco ◽  
Juan Francisco Molina-Lopez
Keyword(s):  
Lichen Planus ◽  
Hidradenitis Suppurativa ◽  
Pyogenic Granuloma ◽  
Perianal Region ◽  
Seborrheic Keratosis ◽  
Lichen Sclerosis

AbstractThis article provides an overview of hidradenitis suppurativa, lichen planus, lichen sclerosis, calcinosis cuti, pyogenic granuloma, intertrigo, and seborrheic keratosis. This article also focuses on recognition and management of these pleomorphic afflictions of the perianal region.

scholarly journals Hidradenitis suppurativa (Verneuil’s disease)

2013 ◽  
Vol 17 (1) ◽  
pp. 1-5 ◽  
Author(s):  
Besma Ben Dhaou ◽  
Fatma Boussema ◽  
Zohra Aydi ◽  
Lilia Baili ◽  
Lilia Rokbani
Keyword(s):  
Hidradenitis Suppurativa ◽  
Verneuil’S Disease

Biologics For Hidradenitis Suppurativa (Verneuil’s Disease in the Era of Biologics)

2006 ◽  
pp. 145-149 ◽  
Author(s):  
Sharon E. Jacob ◽  
Francisco A. Kerdel
Keyword(s):  
Hidradenitis Suppurativa ◽  
Verneuil’S Disease

Adalimumab in Treatment-Resistant Hidradenitis Suppurativa following Recurrence after Extensive Affected Area Excision: A Review of Biologics Therapy

2013 ◽  
Vol 17 (4_suppl) ◽  
pp. S23-S32 ◽  
Author(s):  
Michael Samycia ◽  
Alain Brassard
Keyword(s):  
Clinical Judgment ◽  
Marked Improvement ◽  
Hidradenitis Suppurativa ◽  
Biologic Agents ◽  
Low Grade ◽  
Treatment Resistant ◽  
Perianal Region ◽  
Effective Treatment Modality ◽  
History Of ◽  
Traditional Therapies

Background: Hidradenitis suppurativa (HS) is characterized by chronic, suppurative abscesses, sinus tracts, and fistulas affecting the axilla, groin, and perianal region resulting from hyperkeratosis and occlusion of the terminal hair follicle. Objective: This report highlights the use of biologic agents for the treatment of recalcitrant HS. Method: We report on a 48-year-old male with a 15-year history of refractory perianal-inguinal-buttock HS who, despite receiving numerous surgical drainages and traditional medical treatment for HS, still had severe pain. After trialing etanercept and infliximab with methotrexate, the patient had marked improvement with adalimumab. A literature review of biologics therapy was also performed. Results: After trialing many traditional therapies, we found that adalimumab appears to be the most effective treatment modality for our patient. A literature search revealed 53 articles on biologics therapy in HS. These articles are summarized. Discussion: Biologic agents have been shown to have variable results in the treatment of refractory HS. Enough low-grade evidence has been accumulated to make the use of these agents suitable in HS. Until more clinical trials are performed on this topic, physicians should use clinical judgment when treating HS with biologic agents and be cautious by watching for significant adverse effects.

Host-defense mechanisms in hidradenitis suppurativa

1977 ◽  
Vol 113 (4) ◽  
pp. 450-453 ◽  
Author(s):  
V. C. Dvorak
Keyword(s):  
Host Defense ◽  
Defense Mechanisms ◽  
Hidradenitis Suppurativa

The role of depilation and deodorants in hidradenitis suppurativa

1982 ◽  
Vol 118 (2) ◽  
pp. 101-102 ◽  
Author(s):  
W. P. Morgan
Keyword(s):  
Hidradenitis Suppurativa

Temporary x-ray epilation therapy of chronic axillary hidradenitis suppurativa

1965 ◽  
Vol 92 (6) ◽  
pp. 690-694 ◽  
Author(s):  
I. Zeligman
Keyword(s):  
Hidradenitis Suppurativa ◽  
X Ray ◽  
Axillary Hidradenitis Suppurativa

Surgical treatment of extensive perianal hidradenitis

2020 ◽  
Vol 99 (9) ◽  
Keyword(s):  
Surgical Treatment ◽  
Hidradenitis Suppurativa ◽  
Soft Tissues ◽  
Case Reports ◽  
Radical Excision ◽  
Skin Flaps ◽  
Perianal Area ◽  
Apocrine Glands ◽  
Patient Preparation ◽  
Two Stages

Introduction: Perianal hidradenitis suppurativa is a chronic recurrent inflammatory, suppurative, and fistulising disease of apocrine glands, adjacent anal canal and soft tissues. Perianal area is the second most common affected area after axilla. There are three grades of the disease. Hidradenitis suppurativa represents a chronic, recurrent, deep-seated folliculitis resulting in abscesses, followed by the formation of sinus tracts and subsequent scarring. Perianal hidradenitis suppurativa is the last and the most serious grade of the disease and a specific access is needed for patient preparation and surgical treatment alone. The currently preferred method of treatment for patients with extensive perianal hidradentitis is excision and closure with combination of skin flaps, primary suture and skin graft in one or two stages. Case reports: There are three case reports of perianal hidradenitis suppurativa in this article. The local and overall initial treatment of patients followed by a radical excision and closure with a rotation skin flaps and skin grafts is described. The final results were satisfactory, with no recurrence or serious complication.

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