Improving access and ensuring the quality of melanoma sentinel node biopsy services

2021 ◽  
Vol 91 (12) ◽  
pp. 2561-2562
Author(s):  
Lauren M. Turner ◽  
Mike He ◽  
Frank Piscioneri ◽  
Rebecca Read

2012 ◽  
Vol 30 (15_suppl) ◽  
pp. e19002-e19002
Author(s):  
Fabio Ricci ◽  
Erminio Saralli ◽  
Loreto Giovanni Capuano ◽  
Maurizio Dorkin ◽  
Mario Valleriani ◽  
...  

e19002 Background: Sentinel node biopsy (SNB) is used in the management of melanoma patients without nodal metastases. Methods: From January 1, 1998 to December 31, 2011 we performed 182 SNBs at St. M. Goretti Hospital. Patients presented a primary melanoma, Breslow thickness equal to or higher than 1 mm, lower than 1 mm with regression and/or ulceration, and/or IV-V Clark level, and/or mitotic rate ≥ 1/mm2, according to the 7th edition melanoma staging system. All patients underwent pre-operative lymphoscintigraphy with intradermal injection of 50-70 MBq 99 mTc colloidal albumina particles, 50-80 nm size range, in 0.1-0.2 ml saline solution. We never used blue dye. All patients underwent surgical treatment 4-12 h. later. We performed SNB in day-surgery (DS) under local anaesthesia (LA). Surgery incision was 3-4 cm. This study was approved by an ethics committee, discussed with all patients and informed consent was obtained. Purpose of the study is to investigate the validity of this approach for quality of life and cost reduction. Results: 165 patients underwent SNB, 64 (38.7%) in the inguinal region, 83 (50.3%) in axilla, 1 (0.6%) in the popliteal region, 4 (2.4%) patients showed inguinal bilateral sentinel lymph-node (SLN), 6 (3.6%) axillary bilateral SLN, 4 (2.4%) axillary and 3 (1.8%) inguinal double SLN. The SLN identification rate was 100%. After surgery we distributed a questionnaire to the patients about the acceptability of this approach. In 32 patients SLN was positive. In these patients we performed radical lymphoadenectomy, 12 (37.5%) inguinal and 20 (62.5%) axillary. Conclusions: The results achieved are extremely accurate. This procedure is safe, well accepted by patients (98%), reported better quality of life. The oncological results are absolutely reliable. As regards hospital logistics, operations in DS and LA can be easily managed, leading to a significant cost reduction, 42.15% less expensive than the same operation performed under general anaesthesia.





2009 ◽  
Vol 35 (9) ◽  
pp. 921-927 ◽  
Author(s):  
J.-j. Chen ◽  
X.-y. Huang ◽  
Z.-b. Liu ◽  
T.-w. Chen ◽  
J.-y. Cheng ◽  
...  


2017 ◽  
Vol 24 (8) ◽  
pp. 2071-2079 ◽  
Author(s):  
Rachael L. Morton ◽  
Anh Tran ◽  
Johan Yusof Vessey ◽  
Nick Rowbotham ◽  
Julie Winstanley ◽  
...  


2005 ◽  
Vol 92 (1) ◽  
pp. 17-22 ◽  
Author(s):  
Emmanuel Barranger ◽  
Gil Dubernard ◽  
José Fleurence ◽  
Martine Antoine ◽  
Emile Darai ◽  
...  


2014 ◽  
Vol 24 (4) ◽  
pp. 813-819 ◽  
Author(s):  
Rhonda Farrell ◽  
Val Gebski ◽  
Neville F. Hacker

ObjectivesLeg lymphoedema occurs in up to 60% of women after a complete inguinal-femoral lymphadenectomy for vulvar cancer. To avoid lymphoedema, sentinel lymph node biopsy has become the preferred method of staging. However, false-negative results may influence survival, making the sentinel node procedure unacceptable to many fully informed women. The aims of this study were to measure the quality of life (QoL) in women after a complete lymphadenectomy for vulvar cancer and to quantify the risk to survival these women would be prepared to take with sentinel node biopsy.Materials and MethodsSixty women who had a complete lymphadenectomy for early-stage vulvar cancer participated in structured interviews. The severity of lymphoedema symptoms was recorded. The QoL-adjusted survival was measured using the Utility-Based Questionnaire-Cancer, a cancer-specific validated QoL instrument. The women stated their preference for sentinel node biopsy or complete lymphadenectomy. A “standard-gamble” preference table was used to quantify the degree of risk to survival they would take to avoid lymphoedema.ResultsSeventy-three percent of women reported lymphoedema after complete lymphadenectomy. Women with lymphoedema or leg pain had significantly worse scores for QoL in terms of social activity as well as physical and sexual function. Overall, 80% of women would choose complete lymphadenectomy rather than sentinel node biopsy if the risk of missing a positive lymph node was higher than 1 in 100, but if the risk of missing a positive lymph node was lower than 1 in 100, almost one third of the women would prefer sentinel node biopsy.ConclusionsAlthough women treated for early-stage vulvar cancer report reduced QoL after complete lymphadenectomy, most would choose complete lymphadenectomy over sentinel node biopsy. However, there is an individual level of risk that each woman can define with regard to her preference for the sentinel node procedure. Women with early-stage vulvar cancer should be offered an informed choice between complete lymphadenectomy or sentinel node biopsy.



2013 ◽  
Vol 109 (11) ◽  
pp. 2783-2791 ◽  
Author(s):  
E De Gournay ◽  
A Guyomard ◽  
C Coutant ◽  
S Boulet ◽  
P Arveux ◽  
...  


Head & Neck ◽  
2009 ◽  
Vol 31 (4) ◽  
pp. 503-512 ◽  
Author(s):  
Franziska Schiefke ◽  
Michael Akdemir ◽  
Anette Weber ◽  
Daniel Akdemir ◽  
Susanne Singer ◽  
...  


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