Abstract
Background: ARSDS requires extensive resuscitation and has major physical sequelae. We evaluated the psychiatric sequelae by conducting a systematic review to determine prevalence of symptoms of depression, anxiety disorders and post-traumatic stress disorder (PTSD) following ARDS, as well as their risk factors.Methods: We conducted a search on Pubmed by including all studies meeting our primary endpoint (prevalence of symptoms of depression, anxiety disorders and PTSD following ARDS) and secondary endpoint (associated risk factors). Results: Included studies found prevalence ranging from 16 to 46% for symptoms of depression, 23 to 62% for symptoms of anxiety disorders and 16 to 47% for symptoms of PTSD. The data were too heterogeneous to conduct a meta-analysis. Among the risk factors associated with a risk factor of depression, anxiety disorders or PTSD after ARDS were; factors related to patient (as an history of mental illness) risk factors related to ICU management (as use opioids and benzodiazepine). Effect of severity of ARDS is not known.Conclusion: This systematic review shows that depression, anxiety disorders and PTSD following ARDS are frequent, long-lasting, disabling and have severe psychiatric consequences. Associated risk factors can be identified and among us use of opioids.