scholarly journals Risks of hospitalization for upper gastrointestinal bleeding in users of selective serotonin reuptake inhibitors after Helicobacter pylori eradication therapy: a propensity score matching analysis

2019 ◽  
Vol 50 (9) ◽  
pp. 1001-1008 ◽  
Author(s):  
Chuan-Guo Guo ◽  
Ka Shing Cheung ◽  
Feifei Zhang ◽  
Esther W. Chan ◽  
Lijia Chen ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Propensity Score ◽  
Gastrointestinal Bleeding ◽  
Selective Serotonin Reuptake Inhibitors ◽  
Upper Gastrointestinal Bleeding ◽  
Eradication Therapy ◽  
Helicobacter Pylori Eradication ◽  
Propensity Score Matching Analysis ◽  
Upper Gastrointestinal ◽  
Helicobacter Pylori Eradication Therapy

scholarly journals Case Report: Gastric Mucormycosis- a rare but important differential diagnosis of upper gastrointestinal bleeding in an area of Helicobacter pylori endemicity

2019 ◽  
Vol 4 ◽  
pp. 5 ◽  
Author(s):  
Sudeep Adhikari ◽  
Ajaya Raj Gautam ◽  
Buddhi Paudyal ◽  
Keshav Raj Sigdel ◽  
Buddha Basnyat
Keyword(s):  
Helicobacter Pylori ◽  
Gastrointestinal Bleeding ◽  
Upper Gastrointestinal Bleeding ◽  
Early Recognition ◽  
Early Stage ◽  
Eradication Therapy ◽  
Immunocompromised Host ◽  
Complete Recovery ◽  
H Pylori ◽  
Upper Gastrointestinal

A 57 years female from the hills of Nepal presented with upper gastrointestinal bleeding with gastric ulcer evident on endoscopy. Though initially treated with Helicobacter pylori (H. pylori) eradication therapy alone, biopsy later on revealed both mucormycosis and H. pylori infection. She was then treated with antifungals liposomal amphotericin B followed by posaconazole which led to complete recovery. Mucormycosis is a rare but life-threatening fungal disease of immunocompromised host though our patient was immunocompetent. If recognized and treated at early stage, as in our patient, prognosis is good. A high index of suspicion is required for considering this disease in H. pylori endemic regions such as Nepal, and is crucial for early recognition and treatment.

scholarly journals Ūmino nevarikozinio kraujavimo įvertinimo ir stabdymo protokolas

2005 ◽  
Vol 3 (1) ◽  
pp. 0-0
Author(s):  
Jonas Valantinas
Keyword(s):  
Helicobacter Pylori ◽  
Gastrointestinal Bleeding ◽  
Variceal Bleeding ◽  
Upper Gastrointestinal Bleeding ◽  
Eradication Therapy ◽  
Optimal Timing ◽  
Practical Recommendation ◽  
Early Endoscopy ◽  
Management Recommendations ◽  
Upper Gastrointestinal

Jonas ValantinasVilniaus universiteto Medicinos fakultetoGastroenterologijos, nefrologijos, urologijosir abdominalinės chirurgijos klinika,Santariškių g. 2, LT-08661, VilniusEl paštas: [email protected] Per pastaruosius dešimt metų ūminio nevarikozinio kraujavimo stabdymo metodai pasikeitė. Straipsnyje apžvelgiame šiuolaikinius viršutinės virškinimo trakto dalies kraujavimo metodus, kurie patvirtinti klinikiniais tyrimais grįstomis išvadomis. Esant viršutinės virškinimo trakto dalies kraujavimui, pirmiausia tenka atkurti cirkuliuojančio kraujo tūrį ir, pasikonsultavus su internistu bei chirurgu, nustatyti ankstyvo endoskopinio tyrimo indikacijas. Nors endoskopinio tyrimo reikšme šiuo metu niekas neabejoja, jo atlikimo laikas turi būti nustatomas individualiai. Endoskopinė hemostazė atliekama pacientams, kuriems pakartotinio kraujavimo rizika yra didelė. Sustabdžius kraujavimą, gydymas protonų siurblio inhibitoriais naudingas tik daliai ligonių, kuriems nustatomi ankstyvo pakartotinio kraujavimo endoskopiniai požymiai (matoma nekraujuojanti kraujagyslė, krešulys opos dugne ar aktyvus kraujavimas atliekant endoskopiją). Kraujuojantys ligoniai turi būti ištirti ieškant Helicobacter pylori infekcijos. Nustačius infekciją skiriamas eradikacinis gydymas. Ši apžvalga yra rekomenduojamojo pobūdžio ir gydymo įstaigos turi sudaryti joms priimtinus kraujavimo stabdymo protokolus, atsižvelgdamos į savo išteklius. Reikšminiai žodžiai: ūminis nevarikozinis kraujavimas, kraujavimo stabdymas, endoskopinis tyrimas Acute non-variceal bleeding assessment and hemostasis protocol (A PRACTICAL RECOMMENDATION) Jonas ValantinasVilnius University, Faculty of Medicine Clinic of Gastroenterology,Nephrology, Urology and Abdominal Surgery,Santariškių str. 2, LT-08661 Vilnius, LithuaniaE-mail: [email protected] The management of patients with acute non-variceal upper gastrointestinal bleeding has evolved substantially over the past ten years. This article reviews the currently available treatment methods in cases of upper gastrointestinal bleeding and provides evidence-based management recommendations that address clinically relevant issues. We emphasise an appropriate initial resuscitation of the patient and a multidisciplinary approach to clinical risk stratification that determines the need for early endoscopy. A soon as the effectiveness of upper endoscopy has been established, its optimal timing has to be clearly defined. Endoscopic hemostasis is reserved for patients with high rebleeding risk endoscopic lesions. Routine second look endoscopy is not recommended. Proton pomp inhibitors therapy is useful only in a selected group of patients, namely those with ulcers having endoscopic high risk stigmata of rebleeding (nonbleeding visible vessel, adherent clot or active bleeding at the time of endoscopy). Patients with upper gastrointestinal bleeding should be tested for Helicobacter pylori infection and receive eradication therapy if infection is present. This review should be considered as a recommendation and hospitals should develop institution-specific protocols according to their resources. Keywords: acute non-variceal bleeding, haemostasis, endoscopy

scholarly journals Case Report: Gastric Mucormycosis- a rare but important differential diagnosis of upper gastrointestinal bleeding in an area of Helicobacter pylori endemicity

2019 ◽  
Vol 4 ◽  
pp. 5
Author(s):  
Sudeep Adhikari ◽  
Ajaya Raj Gautam ◽  
Buddhi Paudyal ◽  
Keshav Raj Sigdel ◽  
Buddha Basnyat
Keyword(s):  
Helicobacter Pylori ◽  
Gastrointestinal Bleeding ◽  
Upper Gastrointestinal Bleeding ◽  
Early Recognition ◽  
Early Stage ◽  
Eradication Therapy ◽  
Immunocompromised Host ◽  
Complete Recovery ◽  
H Pylori ◽  
Upper Gastrointestinal

A 57 years female from the hills of Nepal presented with upper gastrointestinal bleeding with gastric ulcer evident on endoscopy. Though initially treated with Helicobacter pylori (H. pylori) eradication therapy alone, biopsy later on revealed both mucormycosis and H. pylori infection. She was then treated with antifungals liposomal amphotericin B followed by posaconazole which led to complete recovery. Mucormycosis is a rare but life-threatening fungal disease of immunocompromised host though our patient was immunocompetent. If recognized and treated at early stage, as in our patient, prognosis is good. A high index of suspicion is required for considering this disease in H. pylori endemic regions such as Nepal, and is crucial for early recognition and treatment.

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