A new insight into cystatin C contained in milk basic protein to bone metabolism: Effects on osteoclasts and osteoblastic MC3T3-E1 cells in vitro

2018 ◽  
Vol 89 (7) ◽  
pp. 1027-1032 ◽  
Author(s):  
Takehiko Yasueda ◽  
Yusuke Abe ◽  
Mayumi Shiba ◽  
Yoshie Kamo ◽  
Yasuyuki Seto
Keyword(s):  
Bone Metabolism ◽  
Cystatin C ◽  
Basic Protein ◽  
Milk Basic Protein ◽  
Insight Into

Milk Basic Protein Increases Bone Mineral Density and Improves Bone Metabolism in Humans

2004 ◽  
pp. 413-429
Author(s):  
Yukihiro Takada ◽  
Seiichiro Aoe ◽  
Yasuhiro Toba ◽  
Kazuhiro Uenishi ◽  
Akira Takeuchi ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Bone Metabolism ◽  
Bone Mineral ◽  
Basic Protein ◽  
Mineral Density ◽  
Milk Basic Protein

Cystatin C in Milk Basic Protein (MBP) and Its Inhibitory Effect on Bone Resorptionin Vitro

2002 ◽  
Vol 66 (12) ◽  
pp. 2531-2536 ◽  
Author(s):  
Yasuhiro MATSUOKA ◽  
Atsushi SERIZAWA ◽  
Tomoe YOSHIOKA ◽  
Jun-ichi YAMAMURA ◽  
Yoshikazu MORITA ◽  
...  
Keyword(s):  
Cystatin C ◽  
Basic Protein ◽  
Inhibitory Effect ◽  
Milk Basic Protein

Milk basic protein increases bone mineral density and improves bone metabolism in healthy young women

2006 ◽  
Vol 18 (3) ◽  
pp. 385-390 ◽  
Author(s):  
K. Uenishi ◽  
H. Ishida ◽  
Y. Toba ◽  
S. Aoe ◽  
A. Itabashi ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Bone Metabolism ◽  
Bone Mineral ◽  
Young Women ◽  
Basic Protein ◽  
Mineral Density ◽  
Milk Basic Protein

Evaluation of milk basic protein supplementation on bone density and bone metabolism in Chinese young women

2009 ◽  
Vol 48 (5) ◽  
pp. 301-306 ◽  
Author(s):  
Zhi-Yong Zou ◽  
Xiao-Ming Lin ◽  
Xian-Rong Xu ◽  
Rui Xu ◽  
Le Ma ◽  
...  
Keyword(s):  
Bone Density ◽  
Bone Metabolism ◽  
Young Women ◽  
Basic Protein ◽  
Protein Supplementation ◽  
Milk Basic Protein

Controlled Trial of the Effects of Milk Basic Protein (MBP) Supplementation on Bone Metabolism in Healthy Adult Women

2001 ◽  
Vol 65 (4) ◽  
pp. 913-918 ◽  
Author(s):  
Seichiro AOE ◽  
Yasuhiro TOBA ◽  
Jun-ichi YAMAMURA ◽  
Hiroshi KAWAKAMI ◽  
Masatoshi YAHIRO ◽  
...  
Keyword(s):  
Bone Metabolism ◽  
Basic Protein ◽  
Healthy Adult ◽  
Controlled Trial ◽  
Adult Women ◽  
Milk Basic Protein

A controlled trial of the effect of milk basic protein (MBP) supplementation on bone metabolism in healthy menopausal women

2005 ◽  
Vol 16 (12) ◽  
pp. 2123-2128 ◽  
Author(s):  
Seiichiro Aoe ◽  
Takao Koyama ◽  
Yasuhiro Toba ◽  
Akira Itabashi ◽  
Yukihiro Takada
Keyword(s):  
Bone Metabolism ◽  
Basic Protein ◽  
Controlled Trial ◽  
Menopausal Women ◽  
Milk Basic Protein

The effect of milk basic protein supplementation on bone metabolism during training of young Thoroughbred racehorses

2006 ◽  
Vol 38 (S36) ◽  
pp. 654-658 ◽  
Author(s):  
Y. INOUE ◽  
Y. ASAI ◽  
M. TOMITA ◽  
K. KURIBARA ◽  
M. KOBAYASHI ◽  
...  
Keyword(s):  
Bone Metabolism ◽  
Basic Protein ◽  
Protein Supplementation ◽  
Thoroughbred Racehorses ◽  
Milk Basic Protein

Co-purification of bone resorbing activity and adenylate cyclase stimulating activity from human tumours associated with the humoral hypercalcaemia of malignancy

1987 ◽  
Vol 114 (1) ◽  
pp. 18-26 ◽  
Author(s):  
Chohei Shigeno ◽  
Itsuo Yamamoto ◽  
Shegiharu Dokoh ◽  
Megumu Hino ◽  
Jun Aoki ◽  
...  
Keyword(s):  
Bone Resorption ◽  
High Performance ◽  
Basic Protein ◽  
Gel Filtration ◽  
Exchange Chromatography ◽  
Protein Factor ◽  
Human Tumours ◽  
Acid Stable ◽  
Bone Resorbing Activity

Abstract. We have partially purified a tumour factor capable of stimulating both bone resorption in vitro and cAMP accumulation in osteoblastic ROS 17/2 cells from three human tumours associated with humoral hypercalcaemia of malignancy. Purification of tumour factor by sequential acid urea extraction, gel filtration and cation-exchange chromatography, reverse-phase high performance liquid chromatography followed by analytical isoelectric focussing provided a basic protein (pI > 9.3) with a molecular weight of approximately 13 000 as a major component of the final preparation which retained both the two bioactivities. Bone resorbing activity and cAMP-increasing activity in purified factor correlated with each other. cAMP-increasing activity of the factor was heat- and acid-stable, but sensitive to alkaline ambient pH. Treatment with trypsin destroyed cAMP-increasing activity of the factor. Synthetic parathyroid hormone (PTH) antagonist, human PTH-(3– 34) completely inhibited the cAMP-increasing activity of the factor. The results suggest that this protein factor, having its effects on both osteoclastic and osteoblastic functions, may be involved in development of enhanced bone resorption in some patients with humoral hypercalcaemia of malignancy.

Effects of TSH and calcitriol on bone metabolism: in vivo and in vitro study

2014 ◽  
Author(s):  
Ivo Dumic-Cule ◽  
Dunja Rogic ◽  
Damir Jezek ◽  
Lovorka Grgurevic ◽  
Slobodan Vukicevic
Keyword(s):  
Bone Metabolism ◽  
In Vitro Study ◽  
Vitro Study
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