Milk basic protein increases bone mineral density and improves bone metabolism in healthy young women

2006 ◽  
Vol 18 (3) ◽  
pp. 385-390 ◽  
Author(s):  
K. Uenishi ◽  
H. Ishida ◽  
Y. Toba ◽  
S. Aoe ◽  
A. Itabashi ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Bone Metabolism ◽  
Bone Mineral ◽  
Young Women ◽  
Basic Protein ◽  
Mineral Density ◽  
Milk Basic Protein

Milk Basic Protein Increases Bone Mineral Density and Improves Bone Metabolism in Humans

2004 ◽  
pp. 413-429
Author(s):  
Yukihiro Takada ◽  
Seiichiro Aoe ◽  
Yasuhiro Toba ◽  
Kazuhiro Uenishi ◽  
Akira Takeuchi ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Bone Metabolism ◽  
Bone Mineral ◽  
Basic Protein ◽  
Mineral Density ◽  
Milk Basic Protein

Milk basic protein increases ghrelin secretion and bone mineral density in rodents

Nutrition ◽  
2017 ◽  
Vol 39-40 ◽  
pp. 15-19 ◽  
Author(s):  
Yuko Ishida ◽  
Rakhi Chacrabati ◽  
Aiko Ono-Ohmachi ◽  
Zhi Gong ◽  
Chika Ikenoya ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Bone Mineral ◽  
Basic Protein ◽  
Mineral Density ◽  
Ghrelin Secretion ◽  
Milk Basic Protein

scholarly journals Milk Basic Protein (MBP) Increases Radial Bone Mineral Density in Healthy Adult Women

2002 ◽  
Vol 66 (3) ◽  
pp. 702-704 ◽  
Author(s):  
Jun-ichi YAMAMURA ◽  
Seiichiro AOE ◽  
Yasuhiro TOBA ◽  
Mutsumi MOTOURI ◽  
Hiroshi KAWAKAMI ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Bone Mineral ◽  
Basic Protein ◽  
Healthy Adult ◽  
Adult Women ◽  
Mineral Density ◽  
Milk Basic Protein ◽  
Radial Bone

scholarly journals Combined effects of soy isoflavones and milk basic protein on bone mineral density in hind-limb unloaded mice

2016 ◽  
Vol 58 (2) ◽  
pp. 141-145 ◽  
Author(s):  
Yu Matsumoto ◽  
Yuko Tousen ◽  
Yoriko Nishide ◽  
Miki Tadaishi ◽  
Ken Kato ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Bone Mineral ◽  
Hind Limb ◽  
Basic Protein ◽  
Soy Isoflavones ◽  
Combined Effects ◽  
Mineral Density ◽  
Milk Basic Protein

Body composition and adipokines influence upon bone mineral density and bone metabolism in renal transplant receivers

2020 ◽  
Author(s):  
Anca Matei ◽  
Stefana Bilha ◽  
Daniela Constantinescu ◽  
Petru Cianga ◽  
Adrian Covic ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Body Composition ◽  
Renal Transplant ◽  
Bone Metabolism ◽  
Bone Mineral ◽  
Mineral Density

Review of the Literature Examining the Association of Serum Uric Acid with Osteoporosis and Mechanistic Insights into Its Effect on Bone Metabolism

2019 ◽  
Vol 19 (3) ◽  
pp. 259-273 ◽  
Author(s):  
Neelam Kaushal ◽  
Divya Vohora ◽  
Rajinder K Jalali ◽  
Sujeet Jha
Keyword(s):  
Risk Factors ◽  
Bone Mineral Density ◽  
Uric Acid ◽  
Bone Metabolism ◽  
Serum Uric Acid ◽  
Bone Mineral ◽  
Molecular Mechanisms ◽  
Association Studies ◽  
Mineral Density ◽  
Age Related

Background And Objective:Osteoporosis is a common bone disorder that increases susceptibility to fragility bone fractures. The clinical and public health repercussions of osteoporosis are huge due to the morbidity, mortality, and cost of medical care linked with fragility fractures. Clinical assessment of osteoporotic risk factors can help to identify candidates at an early stage that will benefit from medical intervention and potentially lowering the morbidity and mortality seen with fractures and complications. Given this, research is ongoing to evaluate the association of osteoporosis with some novel or less well-studied risk factors/bio-markers such as uric acid (UA).Discussion:Uric acid’s antioxidant activity has been proposed to be one of the factors responsible for increasing longevity and lowering rates of age-related cancers during primate evolution, the level of which increased markedly due to loss of uricase enzyme activity (mutational silencing). Accumulated evidence shows that oxidative stress is the fundamental mechanism of age-related bone loss and acts via enhancing osteoclastic activity and increasing bone resorption. Antioxidant substances such as ascorbic acid scavenge free radicals are positively related to bone health. Thus, it is hypothesized that uric acid holds bone-protective potential owing to its potent antioxidative property. Several correlation studies have been conducted globally to investigate the relationship between serum uric acid with bone mineral density and osteoporosis. Few pre-clinical studies have tried to investigate the interaction between uric acid and bone mineral density and reported important role played via Runt-related transcription factor 2 (RUNX2)/core-binding factor subunit alpha-1 (CBF-alpha-1), Wingless-related integration site (Wnt)-3a/β-catenin signaling pathway and 11β Hydroxysteroid Dehydrogenase type 1.Conclusion:In this review, the authors provided a comprehensive summary of the literature related to association studies reported in humans as well work done until date to understand the potential cellular and molecular mechanisms that interplay between uric acid and bone metabolism.

Correlations Between Leptin, Body Composition, Bone Mineral Density, and Bone Metabolism in Kidney Transplant Recipients

2005 ◽  
Vol 37 (5) ◽  
pp. 2151-2153 ◽  
Author(s):  
J. Malyszko ◽  
J.S. Malyszko ◽  
K. Pawlak ◽  
J. Konstantynowicz ◽  
S. Wolczynski ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Body Composition ◽  
Bone Metabolism ◽  
Kidney Transplant ◽  
Bone Mineral ◽  
Transplant Recipients ◽  
Kidney Transplant Recipients ◽  
Mineral Density

The Effect of Hormonal Oral Contraception on Acquisition of Peak Bone Mineral Density of Adolescents and Young Women

2012 ◽  
Vol 25 (3) ◽  
pp. 331-340 ◽  
Author(s):  
Susan Ziglar ◽  
Tracy S. Hunter
Keyword(s):  
Bone Mineral Density ◽  
Bone Mass ◽  
Bone Mineral ◽  
Young Women ◽  
Bone Mineralization ◽  
Critical Time ◽  
Health Concern ◽  
Mineral Density ◽  
Peak Bone Mineral Density ◽  
Bone Mass Accrual

Maximizing bone mass in youth is touted as the best strategy to offset the natural losses of aging and the menopausal transition. Not achieving maximum peak bone mineral density (BMD) is an independent risk factor for osteoporosis and thus a public health concern. Adolescence is a critical time of bone mineralization mediated by endogenous estradiol. Research has shown that the highest velocity of bone mass accrual occurs 1 year before menarche and after the first 3 years. Low-peak attainment of BMD in young women is associated with contributing factors such as diets low in calcium, eating disorders, lack of exercise, smoking, and low estrogen states. Oral contraceptives (OCs) suppress endogenous estradiol production by suppressing the hypothalamic–pituitary–ovarian axis. Thus, OCs, by replacing endogenous estradiol with ethinyl estradiol (EE), establish and maintain new hormone levels. The early initiation and the use of very low dose of EE raises the possibility that bone mass accrual at a critical time of bone mineralization in young women or adolescents may be jeopardized. This review examines the studies of BMD in adolescents and young women that use combination hormonal contraception. Some studies had inherent limitations, such as small trial, poor control of confounders, failure to exclude women with prior use of hormonal contraceptives, or prior pregnancy from control groups. The vast majority of reviewed studies showed OCs containing 20 to 30 µg of EE interfere with acquisition of peak BMD. Limited numbers of studies examine the effects of OCs containing 35 µg on adolescents and young adults. Additionally, studies are needed evaluating the progestin component of OCs as their differing androgenic properties may affect bone mineralization as well.

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