scholarly journals Lack of effect of oral cabotegravir on the pharmacokinetics of a levonorgestrel/ethinyl oestradiol-containing oral contraceptive in healthy adult women

2017 ◽  
Vol 83 (7) ◽  
pp. 1499-1505 ◽  
Author(s):  
Christine Trezza ◽  
Susan L. Ford ◽  
Elizabeth Gould ◽  
Yu Lou ◽  
Chuyun Huang ◽  
...  
Keyword(s):  
Oral Contraceptive ◽  
Healthy Adult ◽  
Adult Women ◽  
Ethinyl Oestradiol

The multiple hit effect: Joint impact of adolescent oral contraceptive use and early adversity on the cortisol awakening response in healthy adult women

2019 ◽  
Vol 100 ◽  
pp. S21
Author(s):  
Catherine Raymond ◽  
Victoria Wolosianski ◽  
Marie-France Marin ◽  
Sonia J. Lupien
Keyword(s):  
Oral Contraceptive ◽  
Contraceptive Use ◽  
Healthy Adult ◽  
Cortisol Awakening Response ◽  
Early Adversity ◽  
Adult Women ◽  
Oral Contraceptive Use ◽  
Multiple Hit

EARLY VARIATIONS OF PLASMA CORTISOL AFTER PULSE INTRAVENOUS INJECTION OF DIBUTYRYL CYCLIC ADENOSINE 3′,5′-MONOPHOSPHATE IN NORMAL SUBJECTS

1973 ◽  
Vol 72 (4) ◽  
pp. 753-761 ◽  
Author(s):  
Alberto Angeli ◽  
Giuseppe Boccuzzi ◽  
Roberto Frajria ◽  
Daniela Bisbocci ◽  
Franco Ceresa
Keyword(s):  
Intravenous Injection ◽  
Plasma Cortisol ◽  
Time Course ◽  
Healthy Adult ◽  
Normal Subjects ◽  
Adult Women ◽  
Healthy Women ◽  
Adrenal Steroidogenesis ◽  
The Mean ◽  
Zero Time

ABSTRACT 10 mg/kg of dibutyryl cyclic adenosine 3′,5′-monophosphate (Db-cAMP) was iv pulse injected into twelve healthy adult women. The plasma cortisol levels were determined as 11-OHCS at zero time and then at 2.5, 5, 7.5, 10, 15, 30, 60 and 180 min after the injection. The data were compared with those obtained at the corresponding times in two groups of eleven and seventeen healthy women after the injection of 250 ng and 250 μg of synthetic β-1-24 corticotrophin performed in the same manner as the injection of the nucleotide. The mean increments in plasma cortisol were significantly lower after Db-cAMP than after ACTH. Differences were noted by analyzing the time course of the responses. In the case of stimulation with Db-cAMP the 11-OHCS levels rose progressively to a maximum at 15–30 min. By contrast, a peak of plasma cortisol was evident in most cases within a few min after the injection of ACTH; after a fall, a later rise was then observed starting from 15 min. The differences in the plasma 11-OHCS responses after the two stimuli may also be of interest clinically for the investigation of some aspects of adrenal steroidogenesis.

The cross-sectional relationship between fortnightly exercise and knee cartilage properties in healthy adult women in midlife

2007 ◽  
Vol 14 (5) ◽  
pp. 830-834 ◽  
Author(s):  
Fahad Hanna ◽  
Andrew J. Teichtahl ◽  
Robin Bell ◽  
Susan R. Davis ◽  
Anita E. Wluka ◽  
...  
Keyword(s):  
Healthy Adult ◽  
Adult Women ◽  
Knee Cartilage ◽  
Cross Sectional ◽  
The Cross

scholarly journals Comparative Analysis of Brain Activation between Healthy Elderly Women and Healthy Adult Women

2011 ◽  
Vol 23 (6) ◽  
pp. 875-878 ◽  
Author(s):  
Byoungkwon Lee ◽  
Dongwook Han
Keyword(s):  
Comparative Analysis ◽  
Healthy Adult ◽  
Elderly Women ◽  
Brain Activation ◽  
Adult Women ◽  
Healthy Elderly

Serum Parathyroid Hormone in Healthy Japanese Women in Relation to Serum 25-Hydroxyvitamin D

2000 ◽  
Vol 70 (6) ◽  
pp. 287-292 ◽  
Author(s):  
Kazutoshi Nakamura ◽  
Mitsue Nashimoto ◽  
Yasushi Hori ◽  
Masaharu Yamamoto
Keyword(s):  
Parathyroid Hormone ◽  
Healthy Adult ◽  
Japanese Women ◽  
Normal Serum ◽  
Adult Women ◽  
Serum Parathyroid Hormone ◽  
Intact Pth ◽  
Hydroxyvitamin D ◽  
25 Hydroxyvitamin D ◽  
The Relationship

The aim of this work was to clarify levels of serum parathyroid hormone (PTH) in healthy adult women and to study the relationship between PTH and 25-hydroxyvitamin D [25(OH)D]. One hundred sixty-nine healthy women aged 40 years or older in a community were studied. The average age of the subjects was 65.3 years (SD 8.2). All subjects had normal serum creatinine levels. Serum intact PTH and 25(OH)D were measured in these subjects. The mean intact PTH concentration was 2.19 pmol/A (SD 1.02). High intact PTH levels above the reference range were observed in four women (2.4%), all of whom were aged 70 years or older. Intact PTH increased with age with a correlation coefficient of 0.192 (p = 0.013). However, there was no correlation (r = –0.125, p = 0.105) between intact PTH and 25(OH)D whose concentrations were more than 37.5 nmol/l. In conclusion, PTH levels of healthy adult Japanese women are lower than previous reports from Western countries, which may be due to the high 25(OH)D levels of the present subjects and/or an ethnic difference. In addition, there is no association between serum 25(OH)D and PTH levels in this Japanese population, supporting a cutoff level of 25(OH)D less than 37.5 nmol/l for the elevated PTH level.

scholarly journals Protein Requirements of Elderly Chinese Adults Are Higher than Current Recommendations

2020 ◽  
Vol 150 (5) ◽  
pp. 1208-1213 ◽  
Author(s):  
Deqian Mao ◽  
Fengge Chen ◽  
Rui Wang ◽  
Ping Bai ◽  
Yanhong Zhang ◽  
...  
Keyword(s):  
Amino Acid ◽  
Healthy Adult ◽  
The Elderly ◽  
Acid Oxidation ◽  
Adult Women ◽  
Chinese Adults ◽  
Amino Acid Oxidation ◽  
Protein Requirements ◽  
Healthy Elderly ◽  
Elderly Chinese

ABSTRACT Background Due to a lack of research data on the protein requirements of the elderly in China, the estimated average requirement (EAR) and the recommended nutrient intake (RNI) of protein in the elderly remain the same as those in young and middle-aged people at 0.98 g/(kg·d). Objective The objective of this study was to determine the protein requirements of healthy Chinese adults >65y old through use of the indicator amino acid oxidation (IAAO) method. Methods Seven healthy adult men and 7 healthy adult women participated in the study, with protein intakes ranging from 0.3 to 1.8 g/(kg·d). The diets were isocaloric and provided energy at a 1.5 resting energy expenditure. Protein was given based on the lactalbumin. Phenylalanine and tyrosine were added to protein doses of 0.3–1.5 g/kg according to the highest dose of protein content [1.8 g/(kg·d)]. Phenylalanine and tyrosine concentrations were kept constant at each protein dose. The mean protein requirement was determined by applying a nonlinear mixed-effects model analysis to the F13CO2, which identified a breakpoint in F13CO2 in response to graded amounts of protein. This trial was registered with the Chinese clinical trial registry as ChiCTR-BOC-17010930. Results Protein EAR and RNI for healthy elderly Chinese adults were determined to be 0.91 and 1.17 g/(kg·d), respectively, based on the indicator amino acid oxidation technique. Conclusions The estimates of protein requirements for Chinese adults >65 y in the present study are 3.4% and 19.4% higher than the current estimated requirements, 0.88 g/(kg·d) for EAR and 0.98 g/(kg·d) for RNI.

Oral contraceptive pill compliance in adolescent/young adult women

1996 ◽  
Vol 18 (2) ◽  
pp. 131 ◽  
Author(s):  
Estherann Grace ◽  
S. Jean Emans ◽  
Elizabeth Goodman
Keyword(s):  
Oral Contraceptive ◽  
Young Adult ◽  
Oral Contraceptive Pill ◽  
Adult Women ◽  
Young Adult Women ◽  
Contraceptive Pill
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