Ancient onset of geographical divergence, interpopulation genetic exchange, and natural selection on theMc1rcoat-colour gene in the house mouse (Mus musculus)

The house mouse, Mus musculus, was established in the early 1900s as one of the first genetic model organisms owing to its short generation time, comparatively large litters, ease of husbandry, and visible phenotypic variants. For these reasons and because they are mammals, house mice are well suited to serve as models for human phenotypes and disease. House mice in the wild consist of at least three distinct subspecies and harbor extensive genetic and phenotypic variation both within and between these subspecies. Wild mice have been used to study a wide range of biological processes, including immunity, cancer, male sterility, adaptive evolution, and non-Mendelian inheritance. Despite the extensive variation that exists among wild mice, classical laboratory strains are derived from a limited set of founders and thus contain only a small subset of this variation. Continued efforts to study wild house mice and to create new inbred strains from wild populations have the potential to strengthen house mice as a model system.

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Dynamics of non-specific esterase during fat resorption in the jejunum of the house mouse, Mus musculus

Histochemistry ◽

10.1007/bf00496740 ◽

1982 ◽

Vol 75 (3) ◽

pp. 377-385 ◽

Cited By ~ 10

Author(s):

A. Böcking ◽

O. v. Deimling

Keyword(s):

House Mouse ◽

Mus Musculus

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Mixed sex allocation strategies in a polytocous mammal, the house mouse (Mus musculus)

Behavioral Ecology and Sociobiology ◽

10.1007/s00265-011-1229-8 ◽

2011 ◽

Vol 65 (12) ◽

pp. 2209-2217 ◽

Cited By ~ 8

Author(s):

Adam Dušek ◽

Luděk Bartoš ◽

František Sedláček

Keyword(s):

House Mouse ◽

Mus Musculus ◽

Sex Allocation ◽

Allocation Strategies ◽

Polytocous Mammal

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Putative Chemical Signals about Sex, Individuality, and Genetic Background in the Preputial Gland and Urine of the House Mouse (Mus musculus)

Chemical Senses ◽

10.1093/chemse/bjl058 ◽

2007 ◽

Vol 32 (3) ◽

pp. 293-303 ◽

Cited By ~ 50

Author(s):

J.-X. Zhang ◽

X.-P. Rao ◽

L. Sun ◽

C.-H. Zhao ◽

X.-W. Qin

Keyword(s):

House Mouse ◽

Mus Musculus ◽

Genetic Background ◽

Chemical Signals ◽

Preputial Gland

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Epigenetic polymorphism in wild populations of Mus musculus

Genetics Research ◽

10.1017/s0016672300003566 ◽

1963 ◽

Vol 4 (2) ◽

pp. 193-220 ◽

Cited By ~ 94

Author(s):

R. J. Berry

Keyword(s):

House Mouse ◽

Mus Musculus ◽

Stabilizing Selection ◽

British Isles ◽

Wild Populations ◽

Local Populations ◽

The World ◽

Different Populations ◽

Different Parts

It has been suggested (Berry & Searle, 1963) that the discontinuous (‘quasi-continuous’) variants studied by Grüneberg et al. in the skeleton of rodents can be regarded as constituting epigenetic polymorphism in different populations. Comparisons have been made between the incidences of skeletal variants in house mouse populations collected from: corn ricks on a single farm in Hampshire; eleven separated localities in different parts of the British Isles; and nine other places throughout the world. These showed that the method could profitably be used for genetically characterizing and hence comparing populations. There was evidence suggestive of genetical drift between local populations and stabilizing selection over a larger area.

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