scholarly journals Emodin inhibits tonic tension through suppressing PKCδ-mediated inhibition of myosin phosphatase in rat isolated thoracic aorta

2014 ◽  
Vol 171 (18) ◽  
pp. 4300-4310 ◽  
Author(s):  
Kyung-Min Lim ◽  
Jae-Hyuk Kwon ◽  
Keunyoung Kim ◽  
Ji-Yoon Noh ◽  
Seojin Kang ◽  
...  
Keyword(s):  
Thoracic Aorta ◽  
Myosin Phosphatase ◽  
Tonic Tension

Dilatation of the entire thoracic aorta in patients with bicuspid aortic valve: a magnetic resonance angiography study

VASA ◽  
2005 ◽  
Vol 34 (3) ◽  
pp. 181-185 ◽  
Author(s):  
Westhoff-Bleck ◽  
Meyer ◽  
Lotz ◽  
Tutarel ◽  
Weiss ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Magnetic Resonance Angiography ◽  
Aortic Valve ◽  
Pulmonary Artery ◽  
Aortic Arch ◽  
Thoracic Aorta ◽  
Aortic Root ◽  
Ascending Aorta ◽  
Descending Aorta ◽  
Severe Aortic Regurgitation

Background: The presence of a bicuspid aortic valve (BAV) might be associated with a progressive dilatation of the aortic root and ascending aorta. However, involvement of the aortic arch and descending aorta has not yet been elucidated. Patients and methods: Magnetic resonance angiography (MRA) was used to assess the diameter of the ascending aorta, aortic arch, and descending aorta in 28 patients with bicuspid aortic valves (mean age 30 ± 9 years). Results: Patients with BAV, but without significant aortic stenosis or regurgitation (n = 10, mean age 27 ± 8 years, n.s. versus control) were compared with controls (n = 13, mean age 33 ± 10 years). In the BAV-patients, aortic root diameter was 35.1 ± 4.9 mm versus 28.9 ± 4.8 mm in the control group (p < 0.01). The diameter of the ascending aorta was also significantly increased at the level of the pulmonary artery (35.5 ± 5.6 mm versus 27.0 ± 4.8 mm, p < 0.001). BAV-patients with moderate or severe aortic regurgitation (n = 18, mean age 32 ± 9 years, n.s. versus control) had a significant dilatation of the aortic root, ascending aorta at the level of the pulmonary artery (41.7 ± 4.8 mm versus 27.0 ± 4.8 mm in control patients, p < 0.001) and, furthermore, significantly increased diameters of the aortic arch (27.1 ± 5.6 mm versus 21.5 ± 1.8 mm, p < 0.01) and descending aorta (21.8 ± 5.6 mm versus 17.0 ± 5.6 mm, p < 0.01). Conclusions: The whole thoracic aorta is abnormally dilated in patients with BAV, particularly in patients with moderate/severe aortic regurgitation. The maximum dilatation occurs in the ascending aorta at the level of the pulmonary artery. Thus, we suggest evaluation of the entire thoracic aorta in patients with BAV.

Management of thoracic aortic lesions - the future is endovascular

VASA ◽  
2012 ◽  
Vol 41 (3) ◽  
pp. 163-176 ◽  
Author(s):  
Weidenhagen ◽  
Bombien ◽  
Meimarakis ◽  
Geisler ◽  
A. Koeppel
Keyword(s):  
Thoracic Aorta ◽  
Clinical Decision Making ◽  
Treatment Options ◽  
Clinical Decision ◽  
Clinical Results ◽  
Treatment Modalities ◽  
Traumatic Rupture ◽  
Descending Thoracic Aorta ◽  
New Treatment ◽  
Aneurysm Dissection

Open surgical repair of lesions of the descending thoracic aorta, such as aneurysm, dissection and traumatic rupture, has been the “state-of-the-art” treatment for many decades. However, in specialized cardiovascular centers, thoracic endovascular aortic repair and hybrid aortic procedures have been implemented as novel treatment options. The current clinical results show that these procedures can be performed with low morbidity and mortality rates. However, due to a lack of randomized trials, the level of reliability of these new treatment modalities remains a matter of discussion. Clinical decision-making is generally based on the experience of the vascular center as well as on individual factors, such as life expectancy, comorbidity, aneurysm aetiology, aortic diameter and morphology. This article will review and discuss recent publications of open surgical, hybrid thoracic aortic (in case of aortic arch involvement) and endovascular repair in complex pathologies of the descending thoracic aorta.

Penetrating atherosclerotic ulcer aneurysm of the innominate artery

VASA ◽  
2009 ◽  
Vol 38 (3) ◽  
pp. 263-266 ◽  
Author(s):  
Yuan ◽  
Tager
Keyword(s):  
Conservative Treatment ◽  
Thoracic Aorta ◽  
Open Surgery ◽  
Innominate Artery ◽  
Ruptured Aneurysm ◽  
Descending Thoracic Aorta ◽  
Penetrating Atherosclerotic Ulcer ◽  
Descending Aorta

Penetrating atherosclerotic ulcer of the aorta is uncommon, and usually develops in the descending thoracic aorta. Rarely this condition involves the branch vessels of the aorta. We report a case of ruptured aneurysm of the innominate artery resulting from penetrating atherosclerotic ulcer. Open surgery was the treatment of choice for the ruptured aneurysm, while conservative treatment was recommended for the associated penetrating atherosclerotic ulcers of the descending aorta.

Short- and long-term outcomes after endovascular management of ruptured descending thoracic aorta

2010 ◽  
Vol 58 (S 01) ◽  
Author(s):  
B Rylski ◽  
M Siepe ◽  
M Südkamp ◽  
C Schlensak ◽  
W Euringer ◽  
...  
Keyword(s):  
Thoracic Aorta ◽  
Endovascular Management ◽  
Descending Thoracic Aorta ◽  
Long Term Outcomes ◽  
Short And Long Term

Secondary interventions and conventional surgical procedures on the descending thoracic aorta in the Marfan-Syndrome

2013 ◽  
Vol 61 (S 01) ◽  
Author(s):  
FA Kari ◽  
P Blanke ◽  
P Peter ◽  
MF Russe ◽  
B Rylski ◽  
...  
Keyword(s):  
Marfan Syndrome ◽  
Thoracic Aorta ◽  
Surgical Procedures ◽  
Descending Thoracic Aorta ◽  
Secondary Interventions

Thoracic Aorta Branch

2020 ◽  
Author(s):  
Keyword(s):  
Thoracic Aorta

Iatrogenic thoracic aortic injury in esophagectomy – a case report and literature review

2019 ◽  
Vol 98 (6) ◽  
pp. 256-259
Keyword(s):  
Case Report ◽  
Minimally Invasive ◽  
Thoracic Aorta ◽  
Aortic Rupture ◽  
Hypovolemic Shock ◽  
Left Lung ◽  
Aortic Injury ◽  
Thoracoscopic Esophagectomy ◽  
Neoadjuvant Radiochemotherapy ◽  
Thoracic Aortic Injury

Introduction: This case report describes bleeding from an iatrogenic thoracic aortic injury in minimally invasive thoracoscopic esophagectomy. Case report: A 53-year-old man underwent neoadjuvant radiochemotherapy for adenocarcinoma of the esophagus with positive lymph nodes. PET/CT showed only a partial response after neoadjuvant therapy. Minimally invasive thoracoscopic esophagectomy in the semi-prone position with selective intuba- tion of the left lung was performed. However, massive bleeding from the thoracic aorta during separation of the tumor resulted in conversion from minimally invasive to conventional right thoracotomy. The bleeding was caused by a five millimeter rupture of the thoracic aorta. The thoracic aortic rupture was treated by suture with a gore prosthesis in collaboration with a vascular surgeon. Esophagestomy was not completed due to hypovolemic shock. Hybrid transhiatal esophagectomy was performed on the seventh day after the primary operation. Definitive histological examination showed T3N3M0 adenocarcinoma. Conclusion: Esophagectomy for cancer of the esophagus is one of the most difficult operations in general surgery in which surgical bleeding from the surrounding structures cannot be excluded. Aortic hemorrhage is hemodynamically significant in all cases and requires urgent surgical treatment.

Surgery Using Median Sternotomy for Diffuse Aneurysmal Disease of the Thoracic Aorta

2004 ◽  
Vol 7 (5) ◽  
pp. E367-E369
Author(s):  
R. Di Bartolomeo ◽  
D. Pacini ◽  
E. Pilato ◽  
C. Savini
Keyword(s):  
Thoracic Aorta ◽  
Median Sternotomy

INTRODUCTION: Symposium on Endovascular Techniques in the Thoracic Aorta

2002 ◽  
Vol 9 (SupplementII) ◽  
pp. II-1-II-1
Author(s):  
Larry H. Hollier
Keyword(s):  
Thoracic Aorta ◽  
Endovascular Techniques

Endovascular Stent-Graft Repair of a Complicated Penetrating Ulcer of the Descending Thoracic Aorta: A Word of Caution

2003 ◽  
Vol 10 (5) ◽  
pp. 928-931 ◽  
Author(s):  
Giuseppe D'Ancona ◽  
Richard Bauset ◽  
Jean-Pierre Normand ◽  
Roc Turcotte ◽  
François Dagenais
Keyword(s):  
Thoracic Aorta ◽  
Stent Graft ◽  
Endovascular Stent ◽  
Descending Thoracic Aorta ◽  
Endovascular Stent Graft ◽  
Penetrating Ulcer ◽  
Stent Graft Repair ◽  
Endovascular Stent Graft Repair
Sign in / Sign up

Export Citation Format

Share Document