Secondary interventions and conventional surgical procedures on the descending thoracic aorta in the Marfan-Syndrome

A 25-year-old male with Marfan Syndrome and previous aortic root surgery presented with severe chest and upper back pain. Initial CT angiogram showed mild aortic dilatation but no acute dissection. Anti-impulse therapy was initiated. Five days after presentation, follow-up CT angiography revealed a new pseudoaneurysm of the descending thoracic aorta. The patient underwent replacement of the mid-descending thoracic aorta with a collagen-impregnated woven polyester tube graft without complication. Despite negative initial imaging and relatively small aortic size, patients with Marfan Syndrome with acute chest pain should be treated with high suspicion and may benefit from admission and serial imaging.

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Altered tissue behavior of a non-aneurysmal descending thoracic aorta in the mouse model of Marfan syndrome

Cell and Tissue Research ◽

10.1007/s00441-011-1270-y ◽

2011 ◽

Vol 347 (1) ◽

pp. 267-277 ◽

Cited By ~ 18

Author(s):

Darren Haskett ◽

Jefferson J. Doyle ◽

Connie Gard ◽

Hwudaurw Chen ◽

Corbie Ball ◽

...

Keyword(s):

Mouse Model ◽

Marfan Syndrome ◽

Thoracic Aorta ◽

Descending Thoracic Aorta

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Replacement of the Descending Thoracic Aorta for Massive Aneurysm in Neonatal Marfan Syndrome

Journal of Cardiac Surgery ◽

10.1111/j.1540-8191.1994.tb00834.x ◽

1994 ◽

Vol 9 (2) ◽

pp. 109-114 ◽

Cited By ~ 1

Author(s):

Giovanni Battista Luciani ◽

Giuseppe Faggian ◽

Alessandro Mazzucco

Keyword(s):

Marfan Syndrome ◽

Thoracic Aorta ◽

Descending Thoracic Aorta ◽

Neonatal Marfan Syndrome

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Management of thoracic aortic lesions - the future is endovascular

VASA ◽

10.1024/0301-1526/a000183 ◽

2012 ◽

Vol 41 (3) ◽

pp. 163-176 ◽

Cited By ~ 6

Author(s):

Weidenhagen ◽

Bombien ◽

Meimarakis ◽

Geisler ◽

A. Koeppel

Keyword(s):

Thoracic Aorta ◽

Clinical Decision Making ◽

Treatment Options ◽

Clinical Decision ◽

Clinical Results ◽

Treatment Modalities ◽

Traumatic Rupture ◽

Descending Thoracic Aorta ◽

New Treatment ◽

Aneurysm Dissection

Open surgical repair of lesions of the descending thoracic aorta, such as aneurysm, dissection and traumatic rupture, has been the state-of-the-art treatment for many decades. However, in specialized cardiovascular centers, thoracic endovascular aortic repair and hybrid aortic procedures have been implemented as novel treatment options. The current clinical results show that these procedures can be performed with low morbidity and mortality rates. However, due to a lack of randomized trials, the level of reliability of these new treatment modalities remains a matter of discussion. Clinical decision-making is generally based on the experience of the vascular center as well as on individual factors, such as life expectancy, comorbidity, aneurysm aetiology, aortic diameter and morphology. This article will review and discuss recent publications of open surgical, hybrid thoracic aortic (in case of aortic arch involvement) and endovascular repair in complex pathologies of the descending thoracic aorta.

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Penetrating atherosclerotic ulcer aneurysm of the innominate artery

VASA ◽

10.1024/0301-1526.38.3.263 ◽

2009 ◽

Vol 38 (3) ◽

pp. 263-266 ◽

Cited By ~ 1

Author(s):

Yuan ◽

Tager

Keyword(s):

Conservative Treatment ◽

Thoracic Aorta ◽

Open Surgery ◽

Innominate Artery ◽

Ruptured Aneurysm ◽

Descending Thoracic Aorta ◽

Penetrating Atherosclerotic Ulcer ◽

Descending Aorta

Penetrating atherosclerotic ulcer of the aorta is uncommon, and usually develops in the descending thoracic aorta. Rarely this condition involves the branch vessels of the aorta. We report a case of ruptured aneurysm of the innominate artery resulting from penetrating atherosclerotic ulcer. Open surgery was the treatment of choice for the ruptured aneurysm, while conservative treatment was recommended for the associated penetrating atherosclerotic ulcers of the descending aorta.

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