scholarly journals Identification of a selective glucocorticoid receptor modulator that prevents both diet-induced obesity and inflammation

2016 ◽  
Vol 173 (11) ◽  
pp. 1793-1804 ◽  
Author(s):  
José K van den Heuvel ◽  
Mariëtte R Boon ◽  
Ingmar van Hengel ◽  
Emma Peschier-van der Put ◽  
Lianne van Beek ◽  
...  
Keyword(s):  
Glucocorticoid Receptor ◽  
Receptor Modulator ◽  
Diet Induced Obesity

The selective glucocorticoid receptor modulator CORT108297 restores faulty hippocampal parameters in Wobbler and corticosterone-treated mice

2014 ◽  
Vol 143 ◽  
pp. 40-48 ◽  
Author(s):  
Maria Meyer ◽  
Maria Claudia Gonzalez Deniselle ◽  
Hazel Hunt ◽  
E. Ronald de Kloet ◽  
Alejandro F. De Nicola
Keyword(s):  
Glucocorticoid Receptor ◽  
Receptor Modulator

Bile acid conjugates of a nonsteroidal glucocorticoid receptor modulator

2004 ◽  
Vol 14 (16) ◽  
pp. 4179-4183 ◽  
Author(s):  
Noah Tu ◽  
J.T Link ◽  
Bryan K Sorensen ◽  
Maurice Emery ◽  
Marlena Grynfarb ◽  
...  
Keyword(s):  
Bile Acid ◽  
Glucocorticoid Receptor ◽  
Receptor Modulator

scholarly journals Safety, pharmacokinetics and pharmacodynamics of the selective glucocorticoid receptor modulator AZD7594, following inhalation in healthy Japanese volunteers

2019 ◽  
Vol Volume 13 ◽  
pp. 3845-3853
Author(s):  
Susanne Prothon ◽  
Ulrika Wählby Hamrén ◽  
Ulrika Tehler ◽  
Esther Yoon ◽  
Henrik Forsman ◽  
...  
Keyword(s):  
Glucocorticoid Receptor ◽  
Pharmacokinetics And Pharmacodynamics ◽  
Receptor Modulator

scholarly journals Discovery of the potent non-steroidal glucocorticoid receptor modulator BAY 1003803 as clinical candidate

2020 ◽  
Vol 30 (16) ◽  
pp. 127298
Author(s):  
Markus Berger ◽  
Ekkehard May ◽  
Hartmut Rehwinkel ◽  
Heike Schäcke ◽  
Roland Neuhaus ◽  
...  
Keyword(s):  
Glucocorticoid Receptor ◽  
Receptor Modulator ◽  
Clinical Candidate

scholarly journals Compound A, a Selective Glucocorticoid Receptor Modulator, Enhances Heat Shock Protein Hsp70 Gene Promoter Activation

PLoS ONE ◽  
2013 ◽  
Vol 8 (7) ◽  
pp. e69115 ◽  
Author(s):  
Ilse M. Beck ◽  
Zuzanna J. Drebert ◽  
Ruben Hoya-Arias ◽  
Ali A. Bahar ◽  
Michael Devos ◽  
...  
Keyword(s):  
Heat Shock ◽  
Heat Shock Protein ◽  
Glucocorticoid Receptor ◽  
Gene Promoter ◽  
Hsp70 Gene ◽  
Promoter Activation ◽  
Compound A ◽  
Receptor Modulator ◽  
Heat Shock Protein Hsp70

Discovery of selective glucocorticoid receptor modulator MK-5932

2011 ◽  
Vol 19 (24) ◽  
pp. 7374-7386 ◽  
Author(s):  
Christopher J. Bungard ◽  
George D. Hartman ◽  
Jesse J. Manikowski ◽  
James J. Perkins ◽  
Chang Bai ◽  
...  
Keyword(s):  
Glucocorticoid Receptor ◽  
Receptor Modulator
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