scholarly journals The impact of COVID ‐19 on obesity services across Europe: A physician survey

2021 ◽  
Author(s):  
Katrin Nather ◽  
Fiachra Bolger ◽  
Laurie DiModica ◽  
Mary Fletcher‐Louis ◽  
Javier Salvador ◽  
...  
Keyword(s):  
Physician Survey ◽  
The Impact

Practice-changing use of the 21-gene oncotype DX breast recurrence score test in Latin American hospitals.

2020 ◽  
Vol 38 (15_suppl) ◽  
pp. e12539-e12539
Author(s):  
Henry Leonidas Gomez ◽  
Juan Enrique Bargallo-Rocha ◽  
Roberto Jorge Billinghurst ◽  
Aníbal Roberto Núñez de Pierro ◽  
Federico Andrés Coló ◽  
...  
Keyword(s):  
Latin America ◽  
Latin American ◽  
Early Stage ◽  
Recurrence Score ◽  
Treatment Decisions ◽  
Treatment Recommendation ◽  
Physician Survey ◽  
Gene Testing ◽  
Gene Test ◽  
The Impact

e12539 Background: The 21-gene test is clinically validated to predict chemotherapy (CT) benefit in node-negative (N0) and node-positive (up to 3 axillary nodes, N+) HR+, HER2− early-stage breast cancer (ESBC). TAILORx showed no CT benefit overall in N0 patients with RS 0-25, but younger patients with RS 16-25 might have some. Clinical guidelines worldwide incorporate the 21-gene test; still, the impact of the test on treatment decisions is unclear in Latin America, where patients often present younger and with more advanced disease. We present a physician survey of the impact of Recurrence Score results on treatment decisions in clinical practice in Latin America. Methods: This multicenter, non-therapeutic, prospective survey enrolled consecutive patients who had 21-gene testing during routine care at 14 community and academic sites in Argentina, Colombia, Mexico, and Peru. Tests were paid for by patients. The physician survey captured patient and tumor characteristics and treatment decisions by physicians pre- and post-assay result. The survey included patients treated before and after TAILORx results reported in 6/2018. Overall net percent change in CT recommendation and 95% Clopper Pearson confidence intervals (CI) were estimated. The proportion with a change between pre-assay treatment recommendation and actual treatment received was calculated overall and by Recurrence Score groups per TAILORx. Results: Between 3/2015 and 12/2019, the survey was completed for 647 patients. 20% had N+ ESBC. Mean patient age was 54 y (24-85 y); 55% were postmenopausal. 17%/63%/20% had grade 1/2/3 tumors; 70%/30% had tumors ≤2/ > 2 cm in size. Recurrence Score results were: 20% RS 0-10, 56% RS 11-25, and 24% RS 26-100. Overall, CT recommendations fell from 325 patients pre-assay to 199 patients post-assay, a 39% decrease (95% CI 33.4 to 44.3) (36% decrease in N0; 46% decrease in N+). The direction of change was consistent with Recurrence Score results. Among N0 patients, the decrease in CT recommendations was 28% (95% CI 18.9 to 39.5) before TAILORx reported and 36% (95% CI 28.4 to 43.7) after. Conclusions: This large survey of 21-gene test practice patterns was the first conducted in Latin America and showed the relevance of 21-gene testing in low- and medium-resource countries to minimize CT over- and underuse in ESBC. Our results showed substantial reductions in CT use overall. After TAILORx, CT use was further reduced, indicating the practice-changing potential of that study.

A Randomized Trial of the Impact of Certified Mail on Response Rate to a Physician Survey, and a Cost-Effectiveness Analysis

1997 ◽  
Vol 20 (4) ◽  
pp. 389-406 ◽  
Author(s):  
Maggi L. del Valle ◽  
Hal Morgenstern ◽  
Teresa L. Rogstad ◽  
Carol Albright ◽  
Barbara G. Vickrey
Keyword(s):  
Cost Effectiveness ◽  
Randomized Trial ◽  
Response Rate ◽  
Cost Effectiveness Analysis ◽  
Physician Survey ◽  
Effectiveness Analysis ◽  
The Impact

scholarly journals Getting Physicians to Respond: The Impact of Incentive Type and Timing on Physician Survey Response Rates

2010 ◽  
Vol 46 (1p1) ◽  
pp. 232-242 ◽  
Author(s):  
Katherine M. James ◽  
Jeanette Y. Ziegenfuss ◽  
Jon C. Tilburt ◽  
Ann M. Harris ◽  
Timothy J. Beebe
Keyword(s):  
Response Rates ◽  
Survey Response ◽  
Physician Survey ◽  
The Impact

The Impact of Changes in HCFA Documentation Requirements on Academic Emergency Medicine Results of a Physician Survey

2001 ◽  
Vol 8 (9) ◽  
pp. 880-885 ◽  
Author(s):  
Samuel A. McLean ◽  
James A. Feldman
Keyword(s):  
Emergency Medicine ◽  
Physician Survey ◽  
The Impact

Physician survey examining the impact of an educational tool for responsible opioid prescribing

2012 ◽  
Vol 8 (2) ◽  
pp. 81-87 ◽  
Author(s):  
Aaron Young, PhD ◽  
Kelly C. Alfred, MS ◽  
Philip P. Davignon, MA ◽  
LaSharn M. Hughes, MBA ◽  
Lisa A. Robin, MLA ◽  
...  
Keyword(s):  
Educational Tool ◽  
Physician Survey ◽  
Opioid Prescribing ◽  
The Impact

Formation of Lunar Craters and Bright Rays as a Result of Meteorite Impacts

1962 ◽  
Vol 14 ◽  
pp. 415-418
Author(s):  
K. P. Stanyukovich ◽  
V. A. Bronshten
Keyword(s):  
Explosive Charge ◽  
The Moon ◽  
Meteorite Impacts ◽  
The Earth ◽  
Lunar Craters ◽  
The Impact

The phenomena accompanying the impact of large meteorites on the surface of the Moon or of the Earth can be examined on the basis of the theory of explosive phenomena if we assume that, instead of an exploding meteorite moving inside the rock, we have an explosive charge (equivalent in energy), situated at a certain distance under the surface.

The Geosciences Applied to Lunar Exploration

1962 ◽  
Vol 14 ◽  
pp. 169-257 ◽  
Author(s):  
J. Green
Keyword(s):  
Lunar Surface ◽  
Probable Mechanism ◽  
Point Of View ◽  
Lunar Exploration ◽  
Geological Model ◽  
Apply Geophysics ◽  
Surface Features ◽  
The Impact

The term geo-sciences has been used here to include the disciplines geology, geophysics and geochemistry. However, in order to apply geophysics and geochemistry effectively one must begin with a geological model. Therefore, the science of geology should be used as the basis for lunar exploration. From an astronomical point of view, a lunar terrain heavily impacted with meteors appears the more reasonable; although from a geological standpoint, volcanism seems the more probable mechanism. A surface liberally marked with volcanic features has been advocated by such geologists as Bülow, Dana, Suess, von Wolff, Shaler, Spurr, and Kuno. In this paper, both the impact and volcanic hypotheses are considered in the application of the geo-sciences to manned lunar exploration. However, more emphasis is placed on the volcanic, or more correctly the defluidization, hypothesis to account for lunar surface features.

Asteroid and Comet Impact Speeds upon Mars: Significance for Panspermia and the Supply of Organics

1997 ◽  
Vol 161 ◽  
pp. 197-201 ◽  
Author(s):  
Duncan Steel
Keyword(s):  
Probability Distributions ◽  
Regions Of Interest ◽  
Significant Fraction ◽  
Organic Chemicals ◽  
Impact Speed ◽  
The Mean ◽  
The Impact

AbstractWhilst lithopanspermia depends upon massive impacts occurring at a speed above some limit, the intact delivery of organic chemicals or other volatiles to a planet requires the impact speed to be below some other limit such that a significant fraction of that material escapes destruction. Thus the two opposite ends of the impact speed distributions are the regions of interest in the bioastronomical context, whereas much modelling work on impacts delivers, or makes use of, only the mean speed. Here the probability distributions of impact speeds upon Mars are calculated for (i) the orbital distribution of known asteroids; and (ii) the expected distribution of near-parabolic cometary orbits. It is found that cometary impacts are far more likely to eject rocks from Mars (over 99 percent of the cometary impacts are at speeds above 20 km/sec, but at most 5 percent of the asteroidal impacts); paradoxically, the objects impacting at speeds low enough to make organic/volatile survival possible (the asteroids) are those which are depleted in such species.

Organic Syntheses During the Impact of a Comet with a Gaseous Planet

1997 ◽  
Vol 161 ◽  
pp. 189-195
Author(s):  
Cesare Guaita ◽  
Roberto Crippa ◽  
Federico Manzini
Keyword(s):  
Polymeric Material ◽  
Molecular Form ◽  
Parent Compound ◽  
Blue Filter ◽  
Organic Syntheses ◽  
The Impact

AbstractA large amount of CO has been detected above many SL9/Jupiter impacts. This gas was never detected before the collision. So, in our opinion, CO was released from a parent compound during the collision. We identify this compound as POM (polyoxymethylene), a formaldehyde (HCHO) polymer that, when suddenly heated, reformes monomeric HCHO. At temperatures higher than 1200°K HCHO cannot exist in molecular form and the most probable result of its decomposition is the formation of CO. At lower temperatures, HCHO can react with NH3 and/or HCN to form high UV-absorbing polymeric material. In our opinion, this kind of material has also to be taken in to account to explain the complex evolution of some SL9 impacts that we observed in CCD images taken with a blue filter.

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