scholarly journals Current knowledge on biomarkers for contact sensitization and allergic contact dermatitis

2017 ◽  
Vol 77 (1) ◽  
pp. 1-16 ◽  
Author(s):  
Sjors A. Koppes ◽  
Kristiane A. Engebretsen ◽  
Tove Agner ◽  
Irena Angelova-Fischer ◽  
Teresa Berents ◽  
...  

2014 ◽  
Vol 27 (2) ◽  
pp. 277
Author(s):  
Ana Rita Travassos ◽  
L. Soares-de-Almeida ◽  
Rui Tato Marinho

Amadeo de Souza-Cardoso, one of the pivotal figures of the Portuguese Modernist movement, studied painting and began his work in Paris where he arrived at the age of 19. Interestingly, Amadeo cemented strong friendships with some physicians from his time. The first was Manuel Laranjeiro, physician, poet and essayist, who has been a major influence on his choice of studying visual arts. In 1909, the painter met the dermatologist Paul Alexander and later Dr. Martins, who diagnosed him with a dermatosis, which led the painter to have to interrupt his work. Described as an eczema, which affected his face and hands, probably an allergic contact dermatitis to paints or other products that did not become clarified, with the artist’s early death at age of 30 by pneumonic fever. Occupational diseases affect the practice of many professions and artists, including painters, who constitute an important risk group. Contact with several components of paints and solvents are associated with the contact sensitization. However, allergens responsible for allergic contact dermatitis change over the time according to the usage trends and products´ composition.



Author(s):  
Anna Tagka ◽  
Alexandros Stratigos ◽  
Panagiotis Stavropoulos ◽  
Dimitrios Rigopoulos ◽  
Argiro Chatziioannou

<p class="abstract"><strong>Background:</strong> Contact dermatitis is a common skin disorder related to environmental exposures affecting, all age groups, and both genders. The pattern of contact sensitization to a series of allergens included in the European baseline series has already been studied for a number of EU countries by the ESSCA Network. The current study aims to explore the patterns of contact dermatitis in Greece through a patch test against a large number of allergens provoking contact dermatitis.</p><p class="abstract"><strong>Methods:</strong> Retrospective analyses of routine data of 668 patients were collected during 2014 in the Laboratory of Patch Testing, National Referral Centre of Occupational Dermatoses. Sensitization in all cases was tested with a battery of 28 allergens of the European baseline series and additional ones aiming to identify new sensitizations to inform the National baseline of allergens; information for an extended MOAHLFA index was also collected.<strong></strong></p><p class="abstract"><strong>Results:</strong> One at least positive result was found in 61.5% of the patients while 19.1% of those found to be sensitized in two or more allergens. Nickel sulphate, fragrance mix and balsam of Peru were the most prevalent allergens in the total population, as well as with respect to gender. Nickel is the most frequent allergen of baseline series, a result which is in agreement with other reports.</p><p class="abstract"><strong>Conclusions:</strong> Allergic contact dermatitis surveillance is of great importance towards the clinical and systematic understanding of the disease. Further studies should be directed towards that end, in order to facilitate more effective health policies.</p>



Author(s):  
Ghanshyam K. Verma ◽  
Saru Thakur ◽  
Gita Ram Tegta ◽  
Ajeet K. Negi ◽  
Saurabh Sharma ◽  
...  

<p class="abstract"><strong>Background:</strong> Skin is exposed to a vast variety of chemicals, organic or biological products among fashion seeking community of today’s world. This put them at risk of contact sensitization. Rapid industrialization, westernization of the society and poor labeling laws of cosmetics put us to the threat of “contact sensitization explosion” in near future. To know the drift of common contact sensitizers in the region, patch testing provides an insight into the cause of allergic contact dermatitis. The objective of the study was to determine the commonest allergen responsible for allergic contact dermatitis among patients attending contact dermatitis clinic in a tertiary care hospital.</p><p class="abstract"><strong>Methods:</strong> This retrospective study was conducted in the Department of Dermatology of our institution. We reviewed the medical records of all patients who were patch tested over a period of 6 years, using Indian standard series.<strong></strong></p><p class="abstract"><strong>Results:</strong> A total of 521 patients who were patch tested in the contact dermatitis clinic were included in the study. Nine patients with angry back were excluded. There were 269 males and 243 females. The commonest provisional diagnosis was allergic contact dermatitis secondary to hair dye in 172 (33.3%) patients followed by air borne contact dermatitis to parthenium in 88 (17.3%) patients. The paraphenylenediamine (PPD) being the most common sensitizer in 92 (17.9%) patients was followed by nickel in 86 (16.7%) patients, potassium dichromate in 36 (7%), parthenium in 32 (6%) and fragrance mix in 31 (6%) patients.</p><p class="abstract"><strong>Conclusions:</strong> This study revealed higher prevalence of hair dye dermatitis. Paraphenylenediamine was the most common allergen.</p>



2018 ◽  
Vol 32 (1) ◽  
pp. 20 ◽  
Author(s):  
PerpetuaU Ibekwe ◽  
EshanB Henshaw ◽  
BobA Ukonu ◽  
Grace Otokpa ◽  
Zainab Babba ◽  
...  




1977 ◽  
Vol 113 (8) ◽  
pp. 1058-1061 ◽  
Author(s):  
D. K. Goette




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