Low anterior resection syndrome in a Scandinavian population of patients with rectal cancer: a longitudinal follow‐up within the QoLiRECT study

BACKGROUND Low anterior resection syndrome (LARS) is a common functional disorder that develops after patients with rectal cancer undergo anal preservation surgery. Common approaches to assess the symptoms of patients with LARS are often complex and time consuming. Instant messaging social media (IMSM) has great application potential in low anterior resection syndrome (LARS) follow-up, but has been underdeveloped. OBJECTIVE To compare data from a novel instant messaging social media (IMSM) follow-up system and a telephone interview (TI) in patients with low anterior resection syndrome (LARS) and to analyse the consistency of the IMSM platform. METHODS R0-resectable rectal cancer patients who accepted several defecation function visits via the IMSM platform and a telephone interview (TI) after the operation using the same questionnaire, including subjective questions and LARS scores, were included. Differences between the two methods were analysed in pairs and the diagnostic consistency of IMSM was calculated based on TI results. RESULTS In total, 21 questionnaires from 15 patients were included. The positive rates of defecation satisfaction, life restriction and medication use were 52.4%, 52.4%, 38.1% for TI and 52.4%, 61.9%, 23.8% for IMSM, respectively. No statistically significant difference was observed between IMSM and TI in terms of total LARS score (22.4 ± 11.9 vs 24.7 ± 10.7,P < 0.213) and LARS categories (Z = −0.264, P = 0.792); however, IMSM showed a more negative tendency. The Kappa values of three subjective questions were 0.618, 0.430 and 0.674, respectively. The total LARS scores were consistent between both groups (Pearson coefficient 0.760, P < 0.001; category correlation coefficient 0.570, P = 0.005). Patients with major LARS had highly consistent results, with sensitivity, specificity, kappa value and p of 77.8%, 91.7%, 0.704 and 0.001, respectively. CONCLUSIONS IMSM can be a significant LARS screening method. However, further research on information accuracy and user acceptance is needed before implementing a mature application. CLINICALTRIAL This study is a subproject of the registered study Bas-1611, which was registered on ClinicalTrail.org website and numbered NCT03009747 in January 2017.

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Comparative analysis of the Memorial Sloan Kettering Bowel Function Instrument and the Low Anterior Resection Syndrome Questionnaire for assessment of bowel dysfunction in rectal cancer patients after low anterior resection

Colorectal Disease ◽

10.1111/codi.15515 ◽

2021 ◽

Author(s):

Felipe F. Quezada‐Diaz ◽

Hossam Elfeki ◽

Katrine J. Emmertsen ◽

Emmanouil P. Pappou ◽

Rosa Jimenez‐Rodriguez ◽

...

Keyword(s):

Rectal Cancer ◽

Comparative Analysis ◽

Cancer Patients ◽

Anterior Resection ◽

Low Anterior Resection ◽

Bowel Function ◽

Bowel Dysfunction ◽

Low Anterior Resection Syndrome ◽

Anterior Resection Syndrome

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The impact of timing of stoma closure on low anterior resection syndrome in patient who underwent low anterior resection for rectal cancer

Kurdistan Journal of Applied Research ◽

10.24017/science.2021.1.13 ◽

2021 ◽

pp. 126-134

Author(s):

Hemn Hussain Kaka Ali ◽

Qalandar Hussein Abdulkarim ◽

Karzan Seerwan ◽

Barham M. M .Salih

Keyword(s):

Rectal Cancer ◽

Anterior Resection ◽

Low Anterior Resection ◽

Anal Verge ◽

Loop Ileostomy ◽

Low Anterior Resection Syndrome ◽

Anterior Resection Syndrome ◽

Closure Of Ileostomy ◽

The Mean ◽

The Impact

This is a multi-center retrospective study of patients underwent low anterior resection for rectal cancer. Ileostomy had been done to protect low lying Colo-rectal anastomosis, closure of ileostomy had been delayed in some patients due to patient own will, surgical complications (anastomotic leak) or coarse of chemotherapy. This study aimed to find the effect of temporary ileostomy on post-operative bowel defunction which is called Low anterior resection syndrome (LARS), and include; urgency, difficulty in emptying of bowel, and incontinence for feces and flatus. A total of 50 patients included in this study, the age ranges from the 19 to 80 years old with a mean age of 51.96 years. The total number of males was (33, %66). Majority of patients were overweight (21, 42%). The distance of tumors from the anal verge were less than 10 cm in (31,62%). The mean duration of fecal diversion was 7.17 months. Loop ileostomy were closed before six months in (27,54%). The mean duration of diversion of patients developed no LARS was 6.87 months which is shorter than those of developed LARS (7.31). Lower BMI patients are more prone to develop LARS, while Obese patients are more susceptible to develop major LARS. Nineteen cases developed LARS among those patient’s ileostomy closed before six months, and 15 cases developed LARS in those ileostomies closed after six months.

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