Incidence, risk factors, and clinical outcomes associated with Epstein‐Barr virus‐DNAemia and Epstein‐Barr virus‐associated disease in patients after haploidentical allogeneic stem cell transplantation: A single‐center study

2020 ◽  
Vol 34 (6) ◽  
Author(s):  
Ling Zhou ◽  
Zhi‐Yong Gao ◽  
Dao‐Pei Lu
2020 ◽  
Vol 27 (2) ◽  
pp. 117
Author(s):  
Su Kyung Kim ◽  
Joon-Sik Choi ◽  
Dongsub Kim ◽  
Cheol-In Kang ◽  
Doo Ryeon Chung ◽  
...  

Cancers ◽  
2020 ◽  
Vol 12 (2) ◽  
pp. 328
Author(s):  
Ayumi Fujimoto ◽  
Ritsuro Suzuki

Epstein-Barr virus (EBV) is a ubiquitous virus belonging to the human γ-herpes virus subfamily. After primary infection, EBV maintains a life-long latent infection. A major concern is that EBV can cause a diverse range of neoplasms and autoimmune diseases. In addition, patients undergoing hematopoietic stem cell transplantation or solid organ transplantation can experience post-transplant lymphoproliferative disorders (PTLDs) due to dysfunction or suppression of host’s immune system, or uncontrolled proliferation of EBV-infected cells. In recent years, the number of EBV-associated PTLD cases has increased. This review focuses on the current understandings of EBV-associated PTLD pathogenesis, as well as the risk factors and clinical outcomes for patients after allogeneic stem cell transplantation.


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