Molluscum-contagiosum-Virus in einer Epidermalzyste

2018 ◽  
Vol 16 (9) ◽  
pp. 1144-1146
Author(s):  
Cornelia Sigrid Lissi Müller ◽  
Michael Laue ◽  
Kim Kremer ◽  
Stephanie Becker ◽  
Thomas Vogt ◽  
...  
Keyword(s):  
Molluscum Contagiosum ◽  
Molluscum Contagiosum Virus

scholarly journals Growth of Molluscum Contagiosum Virus in a Human Foreskin Xenograft Model

Virology ◽  
1996 ◽  
Vol 226 (1) ◽  
pp. 95-101 ◽  
Author(s):  
Kenneth H. Fife ◽  
Margot Whitfeld ◽  
Holly Faust ◽  
Michael P. Goheen ◽  
Janine Bryan ◽  
...  
Keyword(s):  
Xenograft Model ◽  
Molluscum Contagiosum ◽  
Molluscum Contagiosum Virus

scholarly journals Abortive Infection and Transformation of Human Embryonic Fibroblasts by Molluscum contagiosum Virus

1974 ◽  
Vol 24 (2) ◽  
pp. 237-246 ◽  
Author(s):  
G. Barbanti-Brodano ◽  
A. Mannini-Palenzona ◽  
O. Varoli ◽  
M. Portolani ◽  
M. La Placa
Keyword(s):  
Molluscum Contagiosum ◽  
Abortive Infection ◽  
Molluscum Contagiosum Virus ◽  
Embryonic Fibroblasts ◽  
Human Embryonic Fibroblasts

PCR assay fails to detect molluscum contagiosum virus-related sequences in AIDS-related Kaposi's sarcoma

1998 ◽  
Vol 73 (1) ◽  
pp. 83-87 ◽  
Author(s):  
Thierry Simonart ◽  
Jean-Christophe Noël ◽  
Jean-Paul Van Vooren ◽  
Philippe Hermans ◽  
Corine Liesnard ◽  
...  
Keyword(s):  
Kaposi's Sarcoma ◽  
Kaposi’S Sarcoma ◽  
Molluscum Contagiosum ◽  
Molluscum Contagiosum Virus ◽  
Pcr Assay

Molluscum contagiosum virus types in genital and non-genital lesions

1989 ◽  
Vol 120 (1) ◽  
pp. 37-41 ◽  
Author(s):  
C.D. PORTER ◽  
N.W. BLAKE ◽  
L.C. ARCHARD ◽  
M.F. MUHLEMANN ◽  
N. ROSEDALE ◽  
...  
Keyword(s):  
Molluscum Contagiosum ◽  
Molluscum Contagiosum Virus

scholarly journals New Insights into the Evolutionary and Genomic Landscape of Molluscum Contagiosum Virus (MCV) based on Nine MCV1 and Six MCV2 Complete Genome Sequences

Viruses ◽  
2018 ◽  
Vol 10 (11) ◽  
pp. 586 ◽  
Author(s):  
Tomaž Zorec ◽  
Denis Kutnjak ◽  
Lea Hošnjak ◽  
Blanka Kušar ◽  
Katarina Trčko ◽  
...  
Keyword(s):  
Evolutionary History ◽  
Large Scale ◽  
Nk Cell ◽  
Molluscum Contagiosum ◽  
Molluscum Contagiosum Virus ◽  
Genome Sequences ◽  
Viral Interference ◽  
Genomic Landscape ◽  
Genetic Landscape ◽  
Common Skin

Molluscum contagiosum virus (MCV) is the sole member of the Molluscipoxvirus genus and the causative agent of molluscum contagiosum (MC), a common skin disease. Although it is an important and frequent human pathogen, its genetic landscape and evolutionary history remain largely unknown. In this study, ten novel complete MCV genome sequences of the two most common MCV genotypes were determined (five MCV1 and five MCV2 sequences) and analyzed together with all MCV complete genomes previously deposited in freely accessible sequence repositories (four MCV1 and a single MCV2). In comparison to MCV1, a higher degree of nucleotide sequence conservation was observed among MCV2 genomes. Large-scale recombination events were identified in two newly assembled MCV1 genomes and one MCV2 genome. One recombination event was located in a newly identified recombinant region of the viral genome, and all previously described recombinant regions were re-identified in at least one novel MCV genome. MCV genes comprising the identified recombinant segments have been previously associated with viral interference with host T-cell and NK-cell immune responses. In conclusion, the two most common MCV genotypes emerged along divergent evolutionary pathways from a common ancestor, and the differences in the heterogeneity of MCV1 and MCV2 populations may be attributed to the strictness of the constraints imposed by the host immune response.

scholarly journals Role for the conserved N-terminal cysteines in the anti-chemokine activities by the chemokine-like protein MC148R1 encoded by Molluscum contagiosum virus

Virology ◽  
2011 ◽  
Vol 417 (2) ◽  
pp. 449-456 ◽  
Author(s):  
Qingwen Jin ◽  
Jeffrey D. Altenburg ◽  
Mohammad M. Hossain ◽  
Ghalib Alkhatib
Keyword(s):  
Molluscum Contagiosum ◽  
Molluscum Contagiosum Virus

Imiquimod Therapy for Molluscum Contagiosum

2000 ◽  
Vol 4 (2) ◽  
pp. 76-82 ◽  
Author(s):  
Elizabeth Liota ◽  
Kathleen J. Smith ◽  
Ronald Buckley ◽  
Padmen Menon ◽  
Henry Skelton
Keyword(s):  
Molluscum Contagiosum ◽  
Response To Therapy ◽  
Molluscum Contagiosum Virus ◽  
Imiquimod Cream ◽  
Inflammatory Reactions ◽  
Worldwide Distribution ◽  
Double Stranded Dna ◽  
The Family ◽  
Specific Proteins ◽  
Hiv 1

Background: Molluscum contagiosum virus (MCV) is a large double-stranded DNA virus that is a member of the family Poxviridae, and which has a worldwide distribution. As with other poxviruses, MCV does not appear to develop latency but evades the immune system through the production of viral specific proteins. Objective: To evaluate the therapeutic efficacy of imiquimod 5% cream for MCV. Methods: Thirteen children >5 and <10 years old, 19 immune-competent adults and four adults with advanced, but stable HIV-1 disease with >10 MCV lesions were treated with topical 5% imiquimod cream three times weekly for up to 16 weeks. Results: Fourteen of 19 immune-competent adults, four of four adults with HIV-1 disease, and six of 13 children had resolution of their MCV lesions in <16 weeks of imiquimod therapy. Children tended to have more pruritus and inflammatory reactions with imiquimod, although most treated lesions appeared to respond. The development of new MCV lesions resulted in a lower overall resolution of the lesions in children. Imiquimod appeared to be the most efficacious in patients with HIV-1 disease and in the genital area in immune-competent adults. Conclusion: Although topical imiquimod appears to have some efficacy in the therapy of MCV, in children the pruritus correlated relatively well with the development of new lesions. In adults, areas that would be expected to have better penetration appeared to respond more consistently. Although the HIV-1-positive patients had the largest clinical lesions at the onset of therapy, as a group they had the best overall response to therapy.

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