scholarly journals Pharmacokinetic and pharmacodynamic equivalence of Biocon's biosimilar Insulin‐R with the US ‐licensed Humulin® R formulation in healthy subjects: Results from the RHINE ‐1 (Recombinant Human INsulin Equivalence‐1) study

Author(s):  
Leona Plum‐Mörsch el ◽  
Gursharan Singh ◽  
Sundara Moorthi Nainar Murugesan ◽  
Ashwani Marwah ◽  
Jayanti Panda ◽  
...  
1992 ◽  
Vol 267 (18) ◽  
pp. 12692-12699 ◽  
Author(s):  
M.C. Kiefer ◽  
C Schmid ◽  
M Waldvogel ◽  
I Schläpfer ◽  
E Futo ◽  
...  

2018 ◽  
Vol 52 ◽  
pp. 100-105 ◽  
Author(s):  
Jonathan P. Dyke ◽  
Anna Meyring-Wösten ◽  
Yize Zhao ◽  
Peter Linz ◽  
Stephan Thijssen ◽  
...  
Keyword(s):  
The Us ◽  

Allergy ◽  
2003 ◽  
Vol 58 (7) ◽  
pp. 676-678 ◽  
Author(s):  
X Baur ◽  
J Bossert ◽  
F Koops

2016 ◽  
Vol 5 ◽  
pp. 985-991 ◽  
Author(s):  
Magdalena Walicka ◽  
Jacek Jóźwiak ◽  
Jacek Rzeszotarsk ◽  
Grażyna Zarzycka-Lindner ◽  
Anna Zonenberg ◽  
...  

2000 ◽  
Vol 66 (12) ◽  
pp. 5477-5479 ◽  
Author(s):  
Marina Vai ◽  
Luca Brambilla ◽  
Ivan Orlandi ◽  
Nicola Rota ◽  
Bianca Maria Ranzi ◽  
...  

ABSTRACT We studied the secretion of recombinant human insulin-like growth factor 1 (rhIGF-1) from transformed yeast cells. The hIGF-1gene was fused to the mating factor α prepro- leader sequence under the control of the constitutive ACT1 promoter. We found that the inactivation of the GAS1 gene in the host strain led to a supersecretory phenotype yielding a considerable increase, from 8 to 55 mg/liter, in rhIGF-1 production.


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