scholarly journals Intracardiac flow visualization using high‐frame rate blood speckle tracking echocardiography: Illustrations from infants with congenital heart disease

2021 ◽  
Vol 38 (4) ◽  
pp. 707-715
Author(s):  
Massimiliano Cantinotti ◽  
Pietro Marchese ◽  
Martin Koestenberger ◽  
Raffaele Giordano ◽  
Giuseppe Santoro ◽  
...  
Author(s):  
Massimiliano Cantinotti ◽  
Pietro Marchese ◽  
Martin Koestenberger ◽  
Raffaele Giordano ◽  
Giuseppe Santoro ◽  
...  

We report applications of novel high-frame rate blood speckle tracking (BST) echocardiography in a series of infants with congenital heart disease (CHD). BST echocardiography was highly feasible, reproducible, and fast. High-frame rate BST provided complimentary information to conventional color-Doppler data enhancing the visualization and understanding of anomalous blood trajectories (e.g., shunt direction, regurgitant volumes, and stenotic jets) and vortex formation. High-frame rate BST echocardiography is a new, promising imaging tool that may be helpful for deeper understanding of complex CHD physiology.


2019 ◽  
Vol 47 (6) ◽  
pp. 598-604
Author(s):  
Marie-Charlotte Véronique Drop ◽  
Mareike Möllers ◽  
Kerstin Hammer ◽  
Kathrin Oelmeier de Murcia ◽  
Maria Karina Falkenberg ◽  
...  

Abstract Objective To compare myocardial strain and mechanical dyssynchrony in fetuses with congenital heart disease (CHD) to normal controls using speckle tracking echocardiography (STE). Methods In this comparative cross-sectional study 23 fetuses with CHD and 105 normal controls between 19 and 41 weeks of gestation were assessed with STE. The STE sample box was placed over the myocardium of both ventricles. The parameters of interest included the segmental strain of the left (LV-S) and right lateral ventricle wall (RV-S) and the global ventricular strain of both chambers (2C-S). In order to separately assess the LV, we placed the STE sample box over the myocardium of the LV. We calculated the strain of the LV lateral wall (LW-S), the septum (SEPT-S) and the global ventricular strain of the single LV (1C-S). Furthermore, we analyzed the differences in timing of negative peak myocardial strain between the LV and RV (two-chamber dyssynchrony, 2C-DYS) and also within the LV between the lateral wall and the septum (one-chamber dyssynchrony, 1C-DYS). Results The evaluation of strain and mechanical dyssynchrony was feasible in all cases. Compared to normal controls, fetuses with CHD showed lower segmental and global strain values and the extent of 2C-DYS and 1C-DYS was higher than in the healthy control group. Conclusion The deterioration of myocardial function in CHD can be measured with STE. The assessment of strain and dyssynchrony with STE may be useful for distinguishing fetuses with CHD from healthy fetuses.


2013 ◽  
Vol 30 (4) ◽  
pp. 447-459 ◽  
Author(s):  
Jonathan Forsey ◽  
Mark K Friedberg ◽  
Luc Mertens

2013 ◽  
Vol 30 (8) ◽  
pp. 961-966 ◽  
Author(s):  
Palwasha Mokhles ◽  
Annemien. E. van den Bosch ◽  
Jackie S. Vletter - McGhie ◽  
Ron T. Van Domburg ◽  
Titia P. E. Ruys ◽  
...  

2021 ◽  
Vol 22 (Supplement_1) ◽  
Author(s):  
M Leth-Olsen ◽  
G Doehlen ◽  
H Torp ◽  
SA Nyrnes

Abstract Funding Acknowledgements Type of funding sources: Public grant(s) – National budget only. Main funding source(s): The Joint Research Committee between St. Olavs Hospital and the faculty of Medicine, NTNU. The Norwegian Association for Children with Congenital Heart Disease Research Foundation, FFHB Background   There is a risk of gaseous- and solid micro embolus formation during transcatheter procedures (CATH) and surgery in children with congenital heart disease (CHD). Silent strokes during surgery or CATH may contribute to neurological impairment. NeoDoppler is a non-invasive ultrasound system based on plane wave transmissions to continuously monitor cerebral blood flow in infants with an open fontanelle. Gaseous- and solid micro embolus passing through the ultrasound beam create High Intensity Transient Signals (HITS) in the Doppler signal.  Purpose We aimed to study the amount of HITS during CATH and surgery in infants using NeoDoppler.  Methods   The NeoDoppler probe operates at a frequency of 7.8 MHz. The frame rate is 300 fps and the beam covers a wide cylindrical area (10/35mm width/depth). The system displays a color M-mode Doppler and a spectrogram. The broad ultrasound beam permits prolonged scanning time of each event as the HITS move through the ultrasound beam. The high framerate and color M-mode allows for tracking of embolies in depth. In this study the NeoDoppler probe was attached to the anterior fontanelle of infants with CHD during CATH (n = 15) and cardiac surgery (n = 13). HITS were defined as high intensity signal creating skewed lines in the color M-mode Doppler moving away or towards the probe (blue/red) with a corresponding high intensity signal in the spectrogram. HITS were grouped into single HITS and HITS with curtain effect. Single HITS were defined as single skewed lines in the color M-mode Doppler and spectrogram. HITS with curtain effect were defined as skewed broad lines or multiple intensity increase lines in the color M-mode Doppler with corresponding intensity increase that filled the entire doppler curve. HITS with curtain effect are believed to represent numerous HITS that could not be separated from each other in the spectrogram. HITS were manually detected in an in-house MatLab application. Results   The study group consisted of 28 infants (17 males) with different CHD who underwent CATH or surgery. The median age and weight was 96 days (range 3-240 days) and 5650 g (range 2400-8085 g). HITS were detected in 13/15 patients during CATH with a total of 392 HITS (Median 12, Range 0-149) and in all patients during surgery with a total of 772 HITS (Median 45, Range 11-150).  The picture shows examples of single HITS (panel A) and HITS with curtain effect (panel B). One can appreciate the embolic trajectory pattern in depth over time in the color M-mode Display.  Conclusion   In this study we found that NeoDoppler enables detection of frequent HITS in patients with CHD undergoing surgery or CATH. NeoDoppler could become a useful tool to guide modifications of procedures, with aim to reduce the risk of silent stroke. However, further studies are needed to validate the technique. Abstract Figure.


Author(s):  
Kana Fujikura ◽  
Mohammed Makkiya ◽  
Muhammad Farooq ◽  
Yun Xing ◽  
Wayne Humphrey ◽  
...  

Background: global longitudinal strain (GLS) measures myocardial deformation and is a sensitive modality for detecting subclinical myocardial dysfunction and predicting cardiac outcomes. The accuracy of speckle-tracking echocardiography (STE) is dependent on temporal resolution. A novel software enables relatively high frame rate (Hi-FR) (~200 fps) echocardiographic images acquisition which empowers us to investigate the impact of Hi-FR imaging on GLS analysis. The goal of this pilot study was to demonstrate the feasibility of Hi-FR for STE. Methods: In this prospective study, we acquired echocardiographic images using clinical scanners on patients with normal left ventricular systolic function using Hi-FR and conventional frame rate (Reg-FR) (~50 FPS). GLS values were evaluated on apical 4-, 2- and 3-chamber images acquired in both Hi-FR and Reg-FR. Inter-observer and intra-observer variabilities were assessed in Hi-FR and Reg-FR. Results: There were 143 resting echocardiograms with normal LVEF included in this study. The frame rate of Hi-FR was 190 ± 25 and Reg-FR was 50 ± 3, and the heart rate was 71 ± 13. Strain values measured in Hi-FR were significantly higher than those measured in Reg-FR (all p < 0.001). Inter-observer and intra-observer correlations were strong in both Hi-FR and Reg-FR. Conclusions: We demonstrated that strain values were significantly higher using Hi-FR when compared with Reg-FR in patients with normal LVEF. It is plausible that higher temporal resolution enabled the measurement of myocardial strain at desired time point. The result of this study may inform clinical adoption of the novel technology. Further investigations are necessary to evaluate the value of Hi-FR to assess myocardial strain in stress echocardiography in the setting of tachycardia.


2018 ◽  
Vol 37 (9) ◽  
pp. 2022-2032 ◽  
Author(s):  
Jonathan Poree ◽  
Mathilde Baudet ◽  
Francois Tournoux ◽  
Guy Cloutier ◽  
Damien Garcia

2010 ◽  
Vol 12 (S1) ◽  
Author(s):  
Petra S Niemann ◽  
Helene Houle ◽  
Craig S Broberg ◽  
Michael Silberbach ◽  
Zhiwen Zhou ◽  
...  

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