The history of childhood trauma among individuals with ultra high risk for psychosis is as common as among patients with first-episode schizophrenia

2013 ◽  
Vol 7 (4) ◽  
pp. 414-420 ◽  
Author(s):  
Seda Şahin ◽  
Çağrı Yüksel ◽  
Julide Güler ◽  
Gülşah Karadayı ◽  
Elçin Akturan ◽  
...  
Keyword(s):  
High Risk ◽  
Childhood Trauma ◽  
First Episode ◽  
History Of Childhood ◽  
Ultra High Risk ◽  
History Of ◽  
First Episode Schizophrenia

The relationship of childhood trauma and DNA methylation of NMDA receptor genes in first-episode schizophrenia

Epigenomics ◽  
2021 ◽  
Author(s):  
Camila M Loureiro ◽  
Helene A Fachim ◽  
Fabiana Corsi-Zuelli ◽  
Rosana Shuhama ◽  
Paulo R Menezes ◽  
...  
Keyword(s):  
Dna Methylation ◽  
Childhood Trauma ◽  
Genomic Dna ◽  
First Episode ◽  
Childhood Trauma Questionnaire ◽  
History Of Childhood ◽  
History Of ◽  
First Episode Schizophrenia ◽  
Relationship Of ◽  
The Relationship

Aim: We investigated GRIN1, GRIN2A, GRIN2B and LINE-1 DNA methylation in first-episode schizophrenia patients, their nonaffected siblings and age- and sex-matched controls testing for associations between DNA methylation and exposition to childhood trauma. Materials & methods: The Childhood Trauma Questionnaire evaluated the history of childhood trauma. Genomic DNA was bisulfite converted and pyrosequencing was employed to quantify DNA methylation. Results: GRIN2A, GRIN2B and LINE-1 DNA methylation was not associated with childhood trauma in patients, siblings and controls. Siblings with childhood trauma had hypermethylation at CpG1 of GRIN1 compared with siblings without trauma. Conclusion: Childhood trauma may influence GRIN1 methylation in subjects with liability to psychosis, but not in frank schizophrenia or controls.

Lower LINE-1 methylation in first-episode schizophrenia patients with the history of childhood trauma

Epigenomics ◽  
2015 ◽  
Vol 7 (8) ◽  
pp. 1275-1285 ◽  
Author(s):  
Błażej Misiak ◽  
Elżbieta Szmida ◽  
Paweł Karpiński ◽  
Olga Loska ◽  
Maria M Sąsiadek ◽  
...  
Keyword(s):  
Childhood Trauma ◽  
First Episode ◽  
History Of Childhood ◽  
History Of ◽  
First Episode Schizophrenia

White matter microstructure in ultra-high risk and first episode schizophrenia: A prospective study

2016 ◽  
Vol 247 ◽  
pp. 42-48 ◽  
Author(s):  
Silvia Rigucci ◽  
Giulia Santi ◽  
Valentina Corigliano ◽  
Annamaria Imola ◽  
Camilla Rossi-Espagnet ◽  
...  
Keyword(s):  
White Matter ◽  
High Risk ◽  
Prospective Study ◽  
First Episode ◽  
White Matter Microstructure ◽  
Ultra High Risk ◽  
A Prospective Study ◽  
First Episode Schizophrenia

History of Childhood Physical Trauma Has a Negative Impact On Cognitive Functioning in Individuals at Ultra High Risk for Psychosis

2015 ◽  
Vol 30 ◽  
pp. 1691
Author(s):  
A. Ucok ◽  
U. Cikrikçili ◽  
H. Kaya ◽  
O. Bulbul ◽  
C. Yokusoglu ◽  
...  
Keyword(s):  
High Risk ◽  
Cognitive Functioning ◽  
Negative Impact ◽  
History Of Childhood ◽  
Physical Trauma ◽  
Ultra High Risk ◽  
History Of

Small-world networks in individuals at ultra-high risk for psychosis and first-episode schizophrenia during a working memory task

2013 ◽  
Vol 535 ◽  
pp. 35-39 ◽  
Author(s):  
Kyungun Jhung ◽  
Sung-Hwan Cho ◽  
Ji-Hyun Jang ◽  
Jin Young Park ◽  
Dongkwan Shin ◽  
...  
Keyword(s):  
Working Memory ◽  
High Risk ◽  
Memory Task ◽  
Small World ◽  
First Episode ◽  
Small World Networks ◽  
Ultra High Risk ◽  
First Episode Schizophrenia

Poster #T168 BRAIN STRUCTURE IN SUBGROUPS OF PERSONS AT ULTRA HIGH-RISK (UHR) COMPARED TO FIRST-EPISODE SCHIZOPHRENIA AND HEALTHY PERSONS

2014 ◽  
Vol 153 ◽  
pp. S348-S349
Author(s):  
Igor Nenadic ◽  
Raka Maitra ◽  
Soumyajit Basu ◽  
Maren Dietzek ◽  
Nils Schoenfeld ◽  
...  
Keyword(s):  
High Risk ◽  
Brain Structure ◽  
First Episode ◽  
Ultra High Risk ◽  
First Episode Schizophrenia ◽  
Healthy Persons

Association between impaired brain activity and volume at the sub-region of Broca's area in ultra-high risk and first-episode schizophrenia: A multi-modal neuroimaging study

2016 ◽  
Vol 172 (1-3) ◽  
pp. 9-15 ◽  
Author(s):  
Norichika Iwashiro ◽  
Shinsuke Koike ◽  
Yoshihiro Satomura ◽  
Motomu Suga ◽  
Tatsuya Nagai ◽  
...  
Keyword(s):  
High Risk ◽  
Brain Activity ◽  
First Episode ◽  
Broca’S Area ◽  
Broca's Area ◽  
Ultra High Risk ◽  
Neuroimaging Study ◽  
First Episode Schizophrenia

S12-3. Mismatch negativity in patients with ultra high risk and first episode schizophrenia

2013 ◽  
Vol 124 (8) ◽  
pp. e25
Author(s):  
Tsuyoshi Araki ◽  
Tatsuya Nagai ◽  
Mariko Tada ◽  
Kenji Kirihara ◽  
Kiyoto Kasai
Keyword(s):  
High Risk ◽  
Mismatch Negativity ◽  
First Episode ◽  
Ultra High Risk ◽  
First Episode Schizophrenia
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