scholarly journals Matrix metalloproteinases and their inhibitors – pleiotropic functions in insect immunity and metamorphosis

FEBS Journal ◽  
2021 ◽  
Author(s):  
Andreas Vilcinskas
Keyword(s):  
Matrix Metalloproteinases ◽  
Insect Immunity ◽  
Pleiotropic Functions

Cytokine synergy, collagenases and cartilage collagen breakdown

2003 ◽  
Vol 70 ◽  
pp. 125-133 ◽  
Author(s):  
Tim E. Cawston ◽  
Jenny M. Milner ◽  
Jon B. Catterall ◽  
Andrew D. Rowan
Keyword(s):  
Matrix Metalloproteinases ◽  
Inflammatory Cytokines ◽  
Activator Protein 1 ◽  
Activator Protein ◽  
And Cartilage ◽  
Pro Inflammatory Cytokines

We have investigated proteinases that degrade cartilage collagen. We show that pro-inflammatory cytokines act synergistically with oncastatin M to promote cartilage collagen resorption by the up-regulation and activation of matrix metalloproteinases (MMPs). The precise mechanisms are not known, but involve the up-regulation of c-fos, which binds to MMP promoters at a proximal activator protein-1 (AP-1) site. This markedly up-regulates transcription and leads to higher levels of active MMP proteins.

353 Elevated plasma markers of matrix metalloproteinases type 2 and 9 are independent predictors of diastolic heart failure

2006 ◽  
Vol 5 (1) ◽  
pp. 76-76
Author(s):  
R MARTOS ◽  
J BAUGH ◽  
M LEDWIDGE ◽  
C OLOUGHLIN ◽  
C CONLON ◽  
...  
Keyword(s):  
Heart Failure ◽  
Matrix Metalloproteinases ◽  
Diastolic Heart Failure ◽  
Elevated Plasma ◽  
Plasma Markers

485 Differences in serum activity of matrix metalloproteinases between diabetic and non-diabetic patients with chronic heart failure

2003 ◽  
Vol 2 (1) ◽  
pp. 96-97
Author(s):  
D TZIAKAS ◽  
G CHALIKIAS ◽  
D STAKOS ◽  
H XATZINIKOLAOU ◽  
J PARISSIS ◽  
...  
Keyword(s):  
Heart Failure ◽  
Chronic Heart Failure ◽  
Matrix Metalloproteinases ◽  
Diabetic Patients ◽  
Serum Activity
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