Emphysematous cystitis and pyelonephritis leading to a diagnosis of type 2 diabetes in an older patient

Objectives.We performed continuous glucose monitoring (CGM) to define the features of patients with newly diagnosed type 2 diabetes (T2D) before and after Continuous Subcutaneous Insulin Infusion (CSII) therapy.Methods.This was a retrospective analysis. Newly diagnosed T2D patients (106) were admitted from eight centers in China. They were divided into a younger patient group (<60 years) and an older patient group (≥60 years). Each group was further divided into male and female patients. CSII therapy was maintained for 3 weeks after the glycemic target was reached. CGM was performed 2 times before and after completion of insulin treatment.Results.CGM data showed the expected significant improvement of mean amplitude glycemic excursion (MAGE) with CSII therapy. The older patients had lower hourly glucose concentrations from 0200 to 0700 o’clock compared to the younger patients at baseline. Surprisingly, in the older patient group, the male patients had a potential risk of hypoglycemia after CSII therapy, especially during periods from 2300 to 2400 and 0400 to 0600.Conclusions.Our data suggested that older male patients with newly diagnosed T2D may have lower nocturnal glucose concentrations. This may potentially increase the risk of nocturnal hypoglycemia during CSII therapy. This study was registered with Chinese Clinical Trial Registry, numberCliCTR-TRC-11001218.

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A case of alcohol-related emphysematous cystitis

Ukrainian Journal of Nephrology and Dialysis ◽

10.31450/ukrjnd.1(65).2020.01 ◽

2019 ◽

pp. 3-6

Author(s):

A. Sancı ◽

E. Aydoğ ◽

M.C. Karaburun ◽

E. Süer

Keyword(s):

Diabetes Mellitus ◽

Infectious Disease ◽

Risk Factors ◽

Type 2 Diabetes ◽

Urine Culture ◽

Emphysematous Cystitis ◽

Factors Associated ◽

Classical Risk Factor ◽

Negative Urine Culture

Emphysematous cystitis (EC) is a very rare urinary tract infectious disease that can be fatal if not treated. In general, it frequently occurs in diabetic women and is thought to be associated with gas-producing bacteria. Type 2 diabetes mellitus, immunosuppression, drugs (mostly steroids), neurogenic bladder and instrumentation are the major risk factors of this type of infection. We present a case of emphysematous cystitis in a 53-year-old male, in which the patient does not have any classical risk factors associated with EC other than alcohol consumption. To the best of our knowledge, the only case in the literature where this type of infection develops without a classical risk factor and negative urine culture. It is also one of the rare EC cases that may be associated with alcohol use.

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Case Report: Emphysematous Cystitis and Pyelonephritis Induced by Uterine Prolapse in a Subject With Untreated Diabetes Mellitus

Frontiers in Medicine ◽

10.3389/fmed.2021.658682 ◽

2021 ◽

Vol 8 ◽

Author(s):

Hideyuki Iwamoto ◽

Takatoshi Anno ◽

Haruka Takenouchi ◽

Kaio Takahashi ◽

Megumi Horiya ◽

...

Keyword(s):

Diabetes Mellitus ◽

Type 2 Diabetes ◽

Type 2 Diabetes Mellitus ◽

Uterine Prolapse ◽

Obstructive Uropathy ◽

Urination Disorders ◽

Emphysematous Cystitis ◽

Chronic Hyperglycemia ◽

Tract Infections

Type 2 diabetes mellitus (T2DM) is often accompanied by a lot of complications due to chronic hyperglycemia and inflammation. Emphysematous cystitis and pyelonephritis are rare types of urinary tract infections and are often complicated with DM. Herein, we report a case of emphysematous cystitis and pyelonephritis complicated with untreated DM. In addition, this case was very rare and interesting in that her emphysematous cystitis and pyelonephritis were induced by severe uterine prolapse, obstructive uropathy and urination disorders. Both uterine prolapse and DM should be appropriately treated because both can lead to the development of emphysematous cystitis and pyelonephritis.

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