Mid- to long-term results of total ankle replacement in patients with haemophilic arthropathy: A 10-year follow-up

Haemophilia ◽  
2017 ◽  
Vol 24 (2) ◽  
pp. 307-315 ◽  
Author(s):  
F. Eckers ◽  
D. E. Bauer ◽  
A. Hingsammer ◽  
R. Sutter ◽  
B. Brand ◽  
...  
Keyword(s):  
Total Ankle Replacement ◽  
Long Term Results ◽  
Haemophilic Arthropathy ◽  
Ankle Replacement

scholarly journals Mid- to Long-Term Results of Total Ankle Replacement in Patients with Hemophilic Arthropathy

2017 ◽  
Vol 2 (3) ◽  
pp. 2473011417S0000
Author(s):  
Franziska Eckers ◽  
Andreas Hingsammer ◽  
Reto Sutter ◽  
Stephan Wirth ◽  
Brigitte Brand-Staufer ◽  
...  
Keyword(s):  
Total Ankle Replacement ◽  
Long Term Results ◽  
Implant Survival ◽  
Hemophilic Arthropathy ◽  
Ankle Replacement ◽  
Sf 36 ◽  
The Mean ◽  
Component Loosening

Category: Ankle Arthritis Introduction/Purpose: Hemophilia is a rare hematological disease associated with spontaneous joint hemorrhaging causing hemophilic arthropathy. Symptoms comprise joint pain and deformity, paired with loss of function. In the presence of advanced joint deterioration, therapeutic options are confined to either arthroplasty or arthrodesis. For the ankle, the latter is still referred to as the procedure of choice. However - in light of its capacity to reduce pain while preserving ankle motion - total ankle replacement (TAR) has recently gained acceptance as an alternative. The aim of this study was to investigate the mid- to long-term results of TAR in hemophilic ankle arthropathy. Methods: Seventeen TARs were implanted between 1998 and 2012 (mean age: 43 years). Preoperative demographic and disease specific data, complications and revision surgeries were recorded. With a mean follow-up of 9.3 years (range, 2.2-17.8) implant survival was estimated using Kaplan-Meier analysis. Follow-up assessment of 12 TARs was performed after 9.6 years (5 lost to follow-up). Satisfaction and pain scales, the AOFAS hindfoot-score, and the SF-36 were obtained to assess clinical outcome. Radiographic evaluation of pre- and follow-up radiographs was conducted. Results: Three cases (17.6%) had undergone TAR removal secondary to loosening at an average interval of 7.5 years. The estimated implant survival was 94% at 5, 85% at 10, and 70% at 15 years (95% CI, 11.9-17.7). The mean estimated implant survival was 14.77 years (95% CI, 11.9-17.7). The mean level of satisfaction was 76%, and of pain 2/10 (VAS). ROM had increased significantly (p=0.037). The SF-36 summary scores were comparable to those of a matched standard population. The AOFAS hindfoot-score averaged 81/100 points. Conclusion: TAR is a viable treatment option for advanced hemophilic ankle arthropathy. Based on the herein presented follow- up, implant survival compares to that of non-hemophilic populations. Clinical mid- to long-term results are favorable. However, the majority of follow-up radiographs revealed component loosening and/or periprosthetic lucency. Considering the study population’s young age and specific risk factors, need for revision surgery secondary to symptomatic component loosening may arise.

Long-term Results of Scandinavian Total Ankle Replacement

2017 ◽  
Vol 38 (7) ◽  
pp. 723-731 ◽  
Author(s):  
Helka Koivu ◽  
Ia Kohonen ◽  
Kimmo Mattila ◽  
Eliisa Loyttyniemi ◽  
Hannu Tiusanen
Keyword(s):  
Case Series ◽  
Total Ankle Replacement ◽  
Long Term Results ◽  
Retrospective Case ◽  
Level Of Evidence ◽  
Ankle Replacement ◽  
Evaluation Point ◽  
Subjective Measurements

Background: The purpose of this study was to evaluate the long-term results of the Scandinavian Total Ankle Replacement (STAR) implant in a single center. Methods: Between 1997 and 2002, 34 consecutive ankles were replaced with the STAR ankle prosthesis and reviewed in 2016. Patients were followed both radiologically and clinically; clinical outcomes were measured with the Kofoed ankle score and subjective measurements. The median follow-up period was 159 months (13.3 years; range, 13-202 months). Results: The implant survival rate was 93.9% (95% confidence interval [CI], 92.2%-86.7%) at 5 years, 86.7% (95% CI, 69.3%-96.2%) at 10 years, and 63.6% (95% CI, 30.8%-89.0%) at 15 years. A total of 15 ankles (44%) had been revised: 2 by fusion, 3 by further replacement, 5 by insert exchange, and 5 by bone grafting for marked osteolysis. The improvements in the Kofoed ankle score and Kofoed ankle score for pain were statistically significant at every postoperative evaluation point compared to the preoperative values (all P < .0001), and subjective patient satisfaction was high. Conclusion: Our results were satisfactory and in agreement with previously reported findings of STAR implants. Level of Evidence: Level IV, retrospective case series.

Functional Outcome of Meniscal-Bearing Total Ankle Replacement

2008 ◽  
Vol 98 (1) ◽  
pp. 19-26 ◽  
Author(s):  
Maria Grazia Benedetti ◽  
Alberto Leardini ◽  
Matteo Romagnoli ◽  
Lisa Berti ◽  
Fabio Catani ◽  
...  
Keyword(s):  
Activities Of Daily Living ◽  
Gait Analysis ◽  
Functional Outcome ◽  
Daily Living ◽  
Functional Results ◽  
Total Ankle Replacement ◽  
Long Term Results ◽  
Ankle Replacement

Background: Most clinical studies on total ankle replacement (TAR) report assessments based on traditional clinical scores or radiographic analysis. Only a few studies have used modern instrumentation for quantitative functional analysis during the execution of activities of daily living. The aim of this study was to use gait analysis to compare the functional performance of patients who underwent TAR versus a control population. Methods: A retrospective analysis was performed of ten consecutive patients who had undergone meniscal-bearing TAR. Clinical and functional assessments were performed at a mean follow-up of 34 months with a modified Mazur scoring system and state-of-the-art gait analysis. Results: Gait analysis assessment of TAR at medium-term follow-up showed satisfactory results for all patients, with adequate recovery of range of motion. Because the literature reports unsatisfying long-term results, it is important to evaluate these patients over a longer follow-up period. Conclusions: This study showed that TAR yields satisfactory, but not outstanding, general functional results at nearly 3 years’ follow-up. These gait analysis results highlight the importance of integrating in vivo measurements with the standard clinical assessments of patients who underwent TAR while they perform activities of daily living. These results also emphasize the importance of evaluating the functional outcome of TAR over time. (J Am Podiatr Med Assoc 98(1): 19–26, 2008)

scholarly journals The Talar Body Prosthesis Treated End Stage Ankle Arthrosis

2017 ◽  
Vol 2 (3) ◽  
pp. 2473011417S0001
Author(s):  
Thos Harnroongroj
Keyword(s):  
Surgical Technique ◽  
Ankle Arthrodesis ◽  
Total Ankle Replacement ◽  
Walking Ability ◽  
Prosthesis Failure ◽  
Talocrural Joint ◽  
Ankle Replacement ◽  
End Stage

Category: Ankle Arthritis Introduction/Purpose: Ankle arthrosis creates patient disability. Ankle arthrodesis is treatment of choice which creates ankle stiffness and arthrosis of neighboring joints. Total ankle replacement can preserve ankle motions but the results at mid and long- term follow up needed further evaluation. Talar body prosthesis (TBP) can provide long-term satisfactory foot-ankle function of the ankle sustaining talar body damages. Due to ankle biomechanics is different to hip and knee joints. So, we inserted TBP for treating end stage ankle arthrosis. The present study evaluated outcomes at 5-10 years of follow up and described surgical technique. Methods: Between 2001 and 2011, the TBPs were inserted in 23 ankle arthrosis patients. The data were reviewed. We included grade 3 Bargon and Henkemeyer radiographic grading of ankle arthrosis and deformed talar body. The patient with neurological, hip, knee, mid-foot problems which impeded walking ability and age more than 70 were excluded. The patient consisted of 13 females and 10 males. Mean age at index operation and the latest follow up were 54.70 (39-70) and 61.17 (47-75) years old. Mean BMI at the latest follow up was 25.56 kg/m2 (21.89-29.76). Surgical technique included TBP insertion with addressing and applying tensor fascia lata at the articular end of distal tibia. Pre- and the latest follow up AOFAS (American Orthopaedic Foot and Ankle Society) ankle-hindfoot score and radiographs were reviewed. Neighboring joint arthrosis was evaluated by Kellgren-Lawrence radiographic system. The data was statistically analyzed. Results: Mean follow up duration was 6.48 years (5-10 years). All 23 TBPs maintained congruent talocrural joint. There was no prosthesis failure in term of subsidence into calcaneus and prosthetic stem perforation into talar head at the last follow up. No neighboring joint arthrosis occurred according to the radiographs. The mean range of motion of last follow up was 22.17° of plantar flexion (median 22°, ranged from 15° to 29°) and 0° to 5° of dorsiflexion. The patients could perform activity daily life. Mean AOFAS ankle-hindfoot score at preoperative period and last follow up were 40 points (Median 36, Ranged from 31 to 58) and 74 points (median 75, ranged from 61 to 83), respectively. The statistical analysis showed significant improvement of the score (p<0.001). Conclusion: TBP can provide satisfactory result of ankle-hindfoot functions at 5-10 years follow up. Advantages of the prosthesis over ankle arthrodesis and total ankle replacement included preservation of the ankle motion without neighboring joint arthrosis and no prosthesis failure.

Long-term follow-up of mobile-bearing total ankle replacement in patients with inflammatory joint disease

2013 ◽  
Vol 95-B (12) ◽  
pp. 1656-1661 ◽  
Author(s):  
T. Kraal ◽  
H. J. L. van der Heide ◽  
B. J. van Poppel ◽  
M. Fiocco ◽  
R. G. H. H. Nelissen ◽  
...  
Keyword(s):  
Mobile Bearing ◽  
Total Ankle Replacement ◽  
Joint Disease ◽  
Inflammatory Joint Disease ◽  
Ankle Replacement ◽  
Long Term Follow Up

Mid- to Long-term Results of Supramalleolar Osteotomy

2016 ◽  
Vol 38 (2) ◽  
pp. 124-132 ◽  
Author(s):  
Nicola Krähenbühl ◽  
Lukas Zwicky ◽  
Lilianna Bolliger ◽  
Sabine Schädelin ◽  
Beat Hintermann ◽  
...  
Keyword(s):  
Risk Factors ◽  
Proportional Hazards Model ◽  
Ankle Arthrodesis ◽  
Cox Proportional Hazards ◽  
Total Ankle Replacement ◽  
Cox Proportional Hazards Model ◽  
Long Term Results ◽  
Level Of Evidence ◽  
Ankle Replacement

Background: Good clinical and radiographic short-term results have been reported for patients who underwent realignment surgery of the hindfoot for treatment of early- and mid-stage ankle osteoarthrosis (OA). However, no mid- to long-term results have been reported. The aim of this study was to gain a better insight into the indications and contraindications for realignment surgery. Methods: Two hundred ninety-four patients (298 ankles) underwent realignment surgery between December 1999 and June 2013. Kaplan-Meier survival analysis was performed with total ankle replacement and arthrodesis of the ankle joint as endpoints. A Cox proportional hazards model was performed to identify risk factors for failure. The mean time to follow-up was 5.0 ± 3.7 years. Results: The overall 5-year survival rate was 88%. Thirty-eight patients (12.9%) underwent either secondary total ankle replacement or ankle arthrodesis (30 total ankle replacements, 8 ankle arthrodesis). Risk factors for failure following realignment surgery were age at the time of surgery and a Takakura score of 3b preoperatively. Conclusion: Realignment surgery of the hindfoot was an excellent treatment option for young and physically active patients with early to mid-stage ankle OA. Level of Evidence: Level IV, prospective observational study.

scholarly journals Mid- to Long-Term Results of Supramalleolar Osteotomy

2017 ◽  
Vol 2 (3) ◽  
pp. 2473011417S0002
Author(s):  
Nicola Krähenbühl ◽  
Lukas Zwicky ◽  
Lilianna Bolliger ◽  
Beat Hintermann ◽  
Markus Knupp
Keyword(s):  
Risk Factors ◽  
Survival Rate ◽  
Ankle Arthrodesis ◽  
Long Term Results ◽  
Ankle Osteoarthritis ◽  
Time Of Surgery ◽  
Ankle Replacement ◽  
Active Patients

Category: Ankle Arthritis Introduction/Purpose: Good clinical and radiographic short-term results have been reported for patients who underwent realignment surgery of the hindfoot for treatment of early- and mid-stage ankle osteoarthritis. However, no mid- to long-term results have been reported. The aim of this study was to gain a better insight on the indications and contraindications for supramalleolar osteotomies. More specific, we assessed the survival rate of a consecutive cohort of 294 patients who underwent supramalleolar osteotomy for ankle osteoarthritis and investigated the effect on functional outcome, pain relief and patients’ satisfaction. Risk factors for failure were additionally determined. We hypothesized, that realignment surgery is a valuable treatment option for young and physically active patients suffering from early to mid-stage ankle osteoarthritis. Methods: Two hundred and ninety-four patients (298 ankles) underwent realignment surgery between December 1999 and June 2013 in our institution. For four patients who were operated on both feet, only the measurements from the foot operated first were used for further analysis. The patients were assessed clinically and radiographically preoperatively, six and 16 weeks postoperatively and thereafter annually. The examination was done by independent examiners who were not involved in the treatment of the patients or analysis of the data. Kaplan-Meier survival analysis was performed with total ankle replacement and arthrodesis of the ankle joint as endpoints. A Cox proportional hazards model was performed to identify risk factors for failure. Results: The mean time to follow-up was 5.0 ± 3.7 years. The overall five-year survival rate was 88%. Thirty-eight patients (12.9%) either underwent secondary total ankle replacement or ankle arthrodesis (thirty total ankle replacements, eight ankle arthrodesis). A lost to follow-up was reported in eleven patients (3.7%). Overall, the AOFAS Hindfoot score increased from 53.2 preoperatively (SD, 19.9) to 72.7 (SD, 19.2) postoperatively. Risk factors for failure following realignment surgery were age at the time of surgery and a Takakura score of 3b preoperatively. An interaction by trend was also found between age and smoking, indicating that the increased risk in elderly patients was larger in smokers than in non-smokers at the time of surgery. Conclusion: We found good mid- to long-term results for supramalleolar osteotomies in patients with ankle osteoarthritis. The present data suggests that corrective osteotomies need to be considered in the surgical treatment of young and active patients with early- to mid-stage ankle osteoarthritis (Takakura stage 1 to 3a). This is particularly important, as ankle replacement at young age cannot be considered a lifetime solution. However, care should be taken in elderly patients who smoke at the time of surgery.

Surgical reconstruction for unilateral iliac artery lesions in patients younger than 50 years

VASA ◽  
2011 ◽  
Vol 40 (6) ◽  
pp. 474-481 ◽  
Author(s):  
Radak ◽  
Babic ◽  
Ilijevski ◽  
Jocic ◽  
Aleksic ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Limb Salvage ◽  
Iliac Artery ◽  
Graft Patency ◽  
Long Term Results ◽  
Surgical Reconstruction ◽  
Safe Procedure ◽  
Term Survival

Background: To evaluate safety, short and long-term graft patency, clinical success rates, and factors associated with patency, limb salvage and mortality after surgical reconstruction in patients younger than 50 years of age who had undergone unilateral iliac artery bypass surgery. Patients and methods: From January 2000 to January 2010, 65 consecutive reconstructive vascular operations were performed in 22 women and 43 men of age < 50 years with unilateral iliac atherosclerotic lesions and claudication or chronic limb ischemia. All patients were followed at 1, 3, 6, and 12 months after surgery and every 6 months thereafter. Results: There was in-hospital vascular graft thrombosis in four (6.1 %) patients. No in-hospital deaths occurred. Median follow-up was 49.6 ± 33 months. Primary patency rates at 1-, 3-, 5-, and 10-year were 92.2 %, 85.6 %, 73.6 %, and 56.5 %, respectively. Seven patients passed away during follow-up of which four patients due to coronary artery disease, two patients due to cerebrovascular disease and one patient due to malignancy. Limb salvage rate after 1-, 3-, 5-, and 10-year follow-up was 100 %, 100 %, 96.3 %, and 91.2 %, respectively. Cox regression analysis including age, sex, risk factors for vascular disease, indication for treatment, preoperative ABI, lesion length, graft diameter and type of pre-procedural lesion (stenosis/occlusion), showed that only age (beta - 0.281, expected beta 0.755, p = 0.007) and presence of diabetes mellitus during index surgery (beta - 1.292, expected beta 0.275, p = 0.026) were found to be significant predictors of diminishing graft patency during the follow-up. Presence of diabetes mellitus during index surgery (beta - 1.246, expected beta 0.291, p = 0.034) was the only variable predicting mortality. Conclusions: Surgical treatment for unilateral iliac lesions in patients with premature atherosclerosis is a safe procedure with a low operative risk and acceptable long-term results. Diabetes mellitus and age at index surgery are predictive for low graft patency. Presence of diabetes is associated with decreased long-term survival.

Short- and Long-Term Results of Total vs Subtotal Thyroid- ectomies in the Surgical Treatment of Graves' Disease

Swiss Surgery ◽  
2001 ◽  
Vol 7 (1) ◽  
pp. 20-24 ◽  
Author(s):  
Robert ◽  
Mariéthoz ◽  
Pache ◽  
Bertin ◽  
Caulfield ◽  
...  
Keyword(s):  
Recurrent Laryngeal Nerve ◽  
Nerve Palsy ◽  
Recurrent Laryngeal Nerve Palsy ◽  
Laryngeal Nerve ◽  
Long Term Results ◽  
Graves Disease ◽  
Laryngeal Nerve Palsy ◽  
Short And Long Term

Objective: Approximately one out of five patients with Graves' disease (GD) undergoes a thyroidectomy after a mean period of 18 months of medical treatment. This retrospective and non-randomized study from a teaching hospital compares short- and long-term results of total (TT) and subtotal thyroidectomies (ST) for this disease. Methods: From 1987 to 1997, 94 patients were operated for GD. Thirty-three patients underwent a TT (mostly since 1993) and 61 a ST (keeping 4 to 8 grams of thyroid tissue - mean 6 g). All patients had received propylthiouracil and/or neo-mercazole and were in a euthyroid state at the time of surgery; they also took potassium iodide (lugol) for ten days before surgery. Results: There were no deaths. Transient hypocalcemia (< 3 months) occurred in 32 patients (15 TT and 17 ST) and persistent hypocalcemia in 8 having had TT. Two patients developed transient recurrent laryngeal nerve palsy after ST (< 3 months). After a median follow-up period of seven years (1-15) with five patients lost to follow-up, 41 patients having had a ST are in a hypothyroid state (73%), thirteen are euthyroid (23%), and two suffered recurrent hyperthyroidism, requiring completion of thyroidectomy. All 33 patients having had TT - with follow-ups averaging two years (0.5-8) - are receiving thyroxin substitution. Conclusions: There were no instances of persistent recurrent laryngeal nerve palsy in either group, but persistent hypoparathyroidism occurred more frequently after TT. Long after ST, hypothyroidism developed in nearly three of four cases, whereas euthyroidy was maintained in only one-fourth; recurrent hyperthyroidy was rare.

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