Mega‐block sampling is not essential for clinically relevant staging of rectal carcinoma resection specimens

2019 ◽  
Vol 75 (5) ◽  
pp. 776-778
Author(s):  
Newton A C S Wong
Keyword(s):  
Rectal Carcinoma ◽  
Block Sampling

Neoadjuvant Chemotherapy and Radiotherapy in Locally Advanced Rectal Carcinoma

2019 ◽  
Vol 23 (1) ◽  
pp. 221-228
Author(s):  
Mohmed Gaber ◽  
Mohamed Alhashemee ◽  
Al Sayed Hassan ◽  
Sahar Hammam
Keyword(s):  
Neoadjuvant Chemotherapy ◽  
Rectal Carcinoma ◽  
Locally Advanced

Variation of mesorectal volume with abdominal fat volume in patients with rectal carcinoma: assessment with MRI

2007 ◽  
Vol 80 (952) ◽  
pp. 242-247 ◽  
Author(s):  
S D Allen ◽  
V Gada ◽  
D M Blunt
Keyword(s):  
Rectal Carcinoma ◽  
Abdominal Fat ◽  
Fat Volume

Tumor Regression Grading After Preoperative Chemoradiotherapy for Locally Advanced Rectal Carcinoma Revisited: Updated Results of the CAO/ARO/AIO-94 Trial

2014 ◽  
Vol 32 (15) ◽  
pp. 1554-1562 ◽  
Author(s):  
Emmanouil Fokas ◽  
Torsten Liersch ◽  
Rainer Fietkau ◽  
Werner Hohenberger ◽  
Tim Beissbarth ◽  
...  
Keyword(s):  
Local Recurrence ◽  
Tumor Cells ◽  
Rectal Carcinoma ◽  
Distant Metastasis ◽  
Cumulative Incidence ◽  
Tumor Regression ◽  
Preoperative Chemoradiotherapy ◽  
Regression Grading ◽  
Clinicopathologic Parameters

Purpose We previously described the prognostic impact of tumor regression grading (TRG) on the outcome of patients with rectal carcinoma treated with preoperative chemoradiotherapy (CRT) in the CAO/ARO/AIO-94 trial. Here we report long-term results after a median follow-up of 132 months. Patients and Methods TRG after preoperative CRT was determined in 386 surgical specimens by the amount of viable tumor cells versus fibrosis, ranging from TRG 4 (no viable tumor cells) to TRG 0 (no signs of regression). Clinicopathologic parameters and TRG were correlated to the cumulative incidence of local recurrence, distant metastasis, and disease-free survival (DFS). Results Ten-year cumulative incidence of distant metastasis and DFS were 10.5% and 89.5% for patients with TRG 4 (complete regression), 29.3% and 73.6% for TRG 2 and 3 (intermediate regression), and 39.6% and 63% for TRG 0 and 1 (poor regression), respectively (P = .005 and P = .008, respectively). On multivariable analysis, residual lymph node metastasis (ypN+) and TRG were the only independent prognostic factors for cumulative incidence of distant metastasis (P < .001 and P = .035, respectively) and DFS (P < .001 and P = .039, respectively), whereas local recurrence was significantly affected by ypN status (P < .001) and lymphatic invasion (P = .026). Conclusion Complete and intermediate tumor regressions were associated with improved long-term outcome in patients with rectal carcinoma after preoperative CRT independent of clinicopathologic parameters. This classification system needs to be prospectively tested in multiple data sets to validate its reproducibility in a wider setting.

Posterior vaginectomy as a practice parameter in rectal carcinoma

1994 ◽  
Vol 37 (5) ◽  
pp. 513-514 ◽  
Author(s):  
Jason D. Green ◽  
James T. Evans ◽  
Ralph Ger
Keyword(s):  
Rectal Carcinoma ◽  
Practice Parameter

Intestinal permeability, vitamin A absorption, alpha-tocopherol, and neopterin in patients with rectal carcinoma treated with chemoradiation

2009 ◽  
Vol 27 (3) ◽  
pp. 690-696 ◽  
Author(s):  
Josef Dvořák ◽  
Bohuslav Melichar ◽  
Radomír Hyšpler ◽  
Lenka Krčmová ◽  
Lubor Urbánek ◽  
...  
Keyword(s):  
Vitamin A ◽  
Intestinal Permeability ◽  
Rectal Carcinoma ◽  
Alpha Tocopherol

Endorectal Ultrasonographic Staging of Rectal Carcinoma

1990 ◽  
Vol 65 (12) ◽  
pp. 1571-1577 ◽  
Author(s):  
RICHARD J. JOCHEM ◽  
CARL C. READING ◽  
ROGER R. DOZOIS ◽  
HERSCHEL A. CARPENTER ◽  
BRUCE G. WOLFF ◽  
...  
Keyword(s):  
Rectal Carcinoma
Sign in / Sign up

Export Citation Format

Share Document