scholarly journals Clinicopathologic Findings in COVID‐19‐Associated Ischemic Enterocolitis

2021 ◽  
Author(s):  
M. Lisa Zhang ◽  
Frank Jacobsen ◽  
Brian J. Pepe‐Mooney ◽  
Mari Mino‐Kenudson ◽  
Vikram Deshpande ◽  
...  
Keyword(s):  
Clinicopathologic Findings

Clinicopathologic Findings of Colorectal Traditional and Sessile Serrated Adenomas in Korea: A Multicenter Study

Digestion ◽  
2008 ◽  
Vol 77 (3-4) ◽  
pp. 178-183 ◽  
Author(s):  
Sang Kil Lee ◽  
Hee Jin Chang ◽  
Tae Il Kim ◽  
Won Ho Kim ◽  
Cheol Keun Park ◽  
...  
Keyword(s):  
Multicenter Study ◽  
Clinicopathologic Findings ◽  
Serrated Adenomas

The Occurrence of Avian Influenza A Subtype H6N2 in Commercial Layer Flocks in Southern California (2000–02): Clinicopathologic Findings

2003 ◽  
Vol 47 (s3) ◽  
pp. 1214-1218 ◽  
Author(s):  
Hailu Kinde ◽  
Deryck H. Read ◽  
Barbara M. Daft ◽  
Marion Hammarlund ◽  
Janet Moore ◽  
...  
Keyword(s):  
Avian Influenza ◽  
Influenza A ◽  
Southern California ◽  
Clinicopathologic Findings

Feline Cutaneous Fibropapillomas: Clinicopathologic Findings and Association with Papillomavirus Infection

2001 ◽  
Vol 38 (3) ◽  
pp. 291-296 ◽  
Author(s):  
F. Y. Schulman ◽  
A. E. Krafft ◽  
T. Janczewski
Keyword(s):  
Papillomavirus Infection ◽  
Clinicopathologic Findings

scholarly journals Clinicopathologic Findings of Micropapillary Carcinomas, according to Tumor Size

2009 ◽  
Vol 76 (6) ◽  
pp. 348 ◽  
Author(s):  
Young Sun Yoo ◽  
Sung Soo Kim ◽  
Seong Pyo Mun ◽  
Kyung Jong Kim ◽  
Jeong Hwan Chang ◽  
...  
Keyword(s):  
Tumor Size ◽  
Clinicopathologic Findings

scholarly journals The BPH/5 Mouse Model of Superimposed Preeclampsia Is Not a Model of HELLP Syndrome

Biology ◽  
2021 ◽  
Vol 10 (11) ◽  
pp. 1179
Author(s):  
Andrea N. Johnston ◽  
Tifini L. Batts ◽  
Ingeborg M. Langohr ◽  
Cambri Moeller ◽  
Chin-Chi Liu ◽  
...  
Keyword(s):  
Liver Disease ◽  
Hellp Syndrome ◽  
Late Gestation ◽  
Hepatic Inflammation ◽  
Placental Development ◽  
Elevated Liver Enzymes ◽  
Tnf Α ◽  
Multisystemic Disease ◽  
Liver Transaminases ◽  
Clinicopathologic Findings

Preeclampsia (PE) is a multisystemic disease of pregnancy affecting 2–8% of women worldwide. PE-induced liver disease is a rare but important complication of pregnancy. The pathogenesis of liver dysfunction in PE is poorly understood, but is correlated with dysregulated angiogenic, inflammatory, and hypoxic events in the early phase of placental development. Because BPH/5 mice develop the maternal and fetal hallmarks of PE during pregnancy, we hypothesized that they may also share the clinicopathologic findings of the human PE-associated hemolysis elevated liver transaminases low platelets (HELLP) syndrome. Using this model, we determined that microangiopathic hemolysis, thrombocytopenia, and elevated liver enzymes do not occur in mid to late gestation. Pregnant BPH/5 mice do not develop histologic evidence of hepatic inflammation, but they do have increased microsteatosis scores at preconception and in mid to late gestation that progress to macrosteatosis in a subset of mice in late gestation. The transcriptional upregulation of TNF-α, CXCL-10, and TLR-2 occurs in mid gestation prior to the onset of macrosteatosis. The BPH/5 female mouse is not a model of HELLP syndrome, but may be a model of fatty liver disease associated with pregnancy.

Abdominal Pain in Patients with Resectable Pancreatic Cancer with Reference to Clinicopathologic Findings

Pancreas ◽  
2001 ◽  
Vol 22 (3) ◽  
pp. 279-284 ◽  
Author(s):  
Takuji Okusaka ◽  
Shuichi Okada ◽  
Hideki Ueno ◽  
Masafumi Ikeda ◽  
Kazuaki Shimada ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Abdominal Pain ◽  
Resectable Pancreatic Cancer ◽  
Clinicopathologic Findings

Comparison of Signalment, Clinicopathologic Findings, Histologic Diagnosis, and Prognosis in Dogs with Glomerular Disease with or without Nephrotic Syndrome

2011 ◽  
Vol 25 (2) ◽  
pp. 206-214 ◽  
Author(s):  
E.S. Klosterman ◽  
G.E. Moore ◽  
J.F. de Brito Galvao ◽  
S.P. DiBartola ◽  
R.P. Groman ◽  
...  
Keyword(s):  
Nephrotic Syndrome ◽  
Glomerular Disease ◽  
Histologic Diagnosis ◽  
Diagnosis And Prognosis ◽  
Clinicopathologic Findings

Cytologic Evaluation of Tumor-Infiltrating Lymphocytes for Adoptive Cell Therapy

2020 ◽  
Vol 153 (4) ◽  
pp. 513-523
Author(s):  
Sara E Monaco ◽  
Liron Pantanowitz ◽  
Juan Xing ◽  
Jackie Cuda ◽  
Udai S Kammula
Keyword(s):  
Clinical Trial ◽  
Cell Therapy ◽  
Metastatic Cancer ◽  
Adoptive Cell Therapy ◽  
Tumor Infiltrating Lymphocytes ◽  
Lymphoid Cells ◽  
Cytotoxic T Cell ◽  
Cell Therapies ◽  
Clinicopathologic Findings ◽  
Infiltrating Lymphocytes

Abstract Objectives Novel immunotherapeutic options for refractory metastatic cancer patients include adoptive cell therapies such as tumor infiltrating lymphocytes (TILs). This study characterizes the clinicopathologic findings in a cohort of TIL specimens. Methods Patients with metastatic malignancy who were eligible had TILs from their metastases grown and expanded and then sent to pathology. Results A total of 11 TIL specimens (10 melanoma, 1 adenocarcinoma) from patients enrolled in an experimental clinical trial were reviewed. All specimens showed more than 200 lymphoid cells, stained positive for lymphoid markers confirming an activated cytotoxic T-cell immunophenotype, and morphologically showed an intermediate-sized population with immature chromatin and frequent mitoses. Six cases (55%) showed large cells with nucleomegaly and prominent nucleoli. Conclusions This report is the first describing cytopathologic findings of autologous TIL therapy including adequacy guidelines and expected cytomorphologic and immunophenotypic findings. To meet this novel clinical demand, a predefined cytology protocol to rapidly process and interpret these specimens needs to be established.

Intestinal-Type Adenocarcinoma of the Sinonasal Tract: A Clinicopathologic Study of 18 Cases

1993 ◽  
Vol 79 (3) ◽  
pp. 205-210 ◽  
Author(s):  
Carmelo Urso ◽  
Maria Benedetta Ninu ◽  
Alessandro Franchi ◽  
Milena Paglierani ◽  
Roberto Bondi
Keyword(s):  
Intestinal Type ◽  
Presenting Symptoms ◽  
Clinicopathologic Study ◽  
Clinicopathologic Findings ◽  
Poorly Differentiated ◽  
Intestinal Type Adenocarcinoma ◽  
Aggressive Tumors ◽  
Well Differentiated ◽  
Colonic Adenocarcinomas

Background Intestinal-type adenocarcinoma (ITAC) of the nose and paranasal sinuses is a relatively rare tumor. It commonly affects subjects exposed to wood or leather dust. Methods The authors present the clinicopathologic findings of 18 cases of sinonasal ITACs and review the proposed histologic classifications. Results All patients, except one, were males; mean age was 60 years (range, 41-79); in 9 cases an occupational exposure to wood or leather dust was found. Common presenting symptoms were epistaxis, nasal obstruction and rhinorrhea. Histologically, tumors were divided into four groups: well-differentiated (G1) ITACs = 3 cases; moderately differentiated (G2) ITACs = 8 cases; poorly differentiated (G3) ITACs = 2 cases; mucinous (M) ITACs = 5 cases. Immunocytochemically, 16/17 cases were positive for carcinoembryonal antigen, 1/17 for somatostatin, and 0/16 cases for gastrin. Conclusions Sinonasal ITACs are aggressive tumors, often diagnosed in a relatively advanced stage. Owing the close similarity of the microscopic aspects, a histologic classification of ITACs analogous to that of colonic adenocarcinomas is proposed.

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