Blue light disrupts the circadian rhythm and create damage in skin cells

2019 ◽  
Vol 41 (6) ◽  
pp. 558-562 ◽  
Author(s):  
K. Dong ◽  
E. C. Goyarts ◽  
E. Pelle ◽  
J. Trivero ◽  
N. Pernodet
Keyword(s):  
Circadian Rhythm ◽  
Blue Light ◽  
Skin Cells

scholarly journals 1399 Blue light disrupts circadian rhythm at night causing direct effects on skin cells

2018 ◽  
Vol 138 (5) ◽  
pp. S237
Author(s):  
K. Dong ◽  
E. Goyarts ◽  
E. Pelle ◽  
N. Pernodet
Keyword(s):  
Circadian Rhythm ◽  
Blue Light ◽  
Direct Effects ◽  
Skin Cells

Blue-light Filtering Intraocular Lenses

2012 ◽  
Vol 06 (02) ◽  
pp. 104 ◽  
Author(s):  
Sally Blackmore-Wright ◽  
Frank Eperjesi ◽  
◽  
Keyword(s):  
Circadian Rhythm ◽  
Blue Light ◽  
Colour Vision ◽  
Intraocular Lenses ◽  
Scotopic Vision ◽  
Eye Health

Blue-light filtering intraocular lenses are purported to reduce the incidence of potentially damaging UV and blue light on the retina. This article reviews their background, the proposed benefits on long-term eye health and the possible disadvantages on circadian rhythm, scotopic vision and colour vision.

scholarly journals Blue Light Therapy and the Circadian Rhythm: Effect on Southern California High School Students

2020 ◽  
Vol 9 (1) ◽  
Author(s):  
Aaron Hoy
Keyword(s):  
High School ◽  
Circadian Rhythm ◽  
High School Students ◽  
Sleep Quality ◽  
Blue Light ◽  
Seasonal Affective Disorder ◽  
Light Therapy ◽  
Patient Experiences ◽  
School Students ◽  
Positive Results

Blue-light therapy is well known for curing patients with Seasonal Affective Disorder (SAD), where the patient experiences depressive factors. In this study I used blue-light therapy in the form of blue-light lightboxes from the comapny Circadian Optics, as seen on shark tank. Instead of using the lightboxes to cure SAD, they were instead used to see if they provoked the participants sleep quality. The participants from Polytechnic highschool were selected from the Badminton Team, where the athletes woke up at five a.m. on school days. This ensured that the crowd was overall tired and fatigued. Over the four week testing course, participants proved positive results.

scholarly journals Can Light Emitted from Smartphone Screens and Taking Selfies Cause Premature Aging and Wrinkles?

2018 ◽  
Vol 8 (4Dec) ◽  
Author(s):  
N Arjmandi ◽  
Gh Mortazavi ◽  
S Zarei ◽  
M Faraz ◽  
S A R Mortazavi
Keyword(s):  
Oxidative Stress ◽  
Reactive Oxygen Species ◽  
Visible Light ◽  
Human Skin ◽  
Blue Light ◽  
Biological Effects ◽  
Premature Aging ◽  
Oxygen Species ◽  
Skin Cells ◽  
Human Skin Cells

Since the early days of human life on the Earth, our skin has been exposed to different levels of light. Recently, due to inevitable consequences of modern life, humans are not exposed to adequate levels of natural light during the day but they are overexposed to relatively high levels of artificial light at night. Skin is a major target of oxidative stress and the link between aging and oxidative stress is well documented. Especially, extrinsic skin aging can be caused by oxidative stress. The widespread use of light emitting diodes (LEDs) and the rapidly increasing use of smartphones, tablets, laptops and desktop computers have led to a significant rise in the exposure of human eyes to short-wavelength visible light. Recent studies show that exposure of human skin cells to light emitted from electronic devices, even for exposures as short as 1 hour, may cause reactive oxygen species (ROS) generation, apoptosis, and necrosis. The biological effects of exposure to short-wavelength visible light in blue region in humans and other living organisms were among our research priorities at the Ionizing and Non-ionizing Radiation Protection Research Center (INIRPRC). Today, there is a growing concern over the safety of the light sources such as LEDs with peak emissions in the blue light range (400-490 nm). Recent studies aimed at investigating the effect of exposure to light emitted from electronic device on human skin cells, shows that even short exposures can increase the generation of reactive oxygen species. However, the biological effects of either long-term or repeated exposures are not fully known, yet. Furthermore, there are reports indicating that frequent exposure to visible light spectrum of the selfie flashes may cause skin damage and accelerated skin ageing. In this paper we have addressed the different aspects of potential effects of exposure to the light emitted from smartphones’ digital screens as well as smartphones’ photoflashes on premature aging of the human skin. Specifically, the effects of blue light on eyes and skin are discussed. Based on current knowledge, it can be suggested that changing the spectral output of LED-based smartphones’ flashes can be introduced as an effective method to reduce the adverse health effects associated with exposure to blue light.

scholarly journals Can Light Emitted from Smartphone Screens and Taking Selfies Cause Premature Aging and Wrinkles?

2018 ◽  
Vol 8 (4 Dec) ◽  
Author(s):  
N Arjmandi ◽  
Gh Mortazavi ◽  
S Zarei ◽  
M Faraz ◽  
S A R Mortazavi
Keyword(s):  
Oxidative Stress ◽  
Reactive Oxygen Species ◽  
Visible Light ◽  
Human Skin ◽  
Blue Light ◽  
Biological Effects ◽  
Premature Aging ◽  
Oxygen Species ◽  
Skin Cells ◽  
Human Skin Cells

Since the early days of human life on the Earth, our skin has been exposed to different levels of light. Recently, due to inevitable consequences of modern life, humans are not exposed to adequate levels of natural light during the day but they are overexposed to relatively high levels of artificial light at night. Skin is a major target of oxidative stress and the link between aging and oxidative stress is well documented. Especially, extrinsic skin aging can be caused by oxidative stress. The widespread use of light emitting diodes (LEDs) and the rapidly increasing use of smartphones, tablets, laptops and desktop computers have led to a significant rise in the exposure of human eyes to short-wavelength visible light. Recent studies show that exposure of human skin cells to light emitted from electronic devices, even for exposures as short as 1 hour, may cause reactive oxygen species (ROS) generation, apoptosis, and necrosis. The biological effects of exposure to short-wavelength visible light in blue region in humans and other living organisms were among our research priorities at the Ionizing and Non-ionizing Radiation Protection Research Center (INIRPRC). Today, there is a growing concern over the safety of the light sources such as LEDs with peak emissions in the blue light range (400-490 nm). Recent studies aimed at investigating the effect of exposure to light emitted from electronic device on human skin cells, shows that even short exposures can increase the generation of reactive oxygen species. However, the biological effects of either long-term or repeated exposures are not fully known, yet. Furthermore, there are reports indicating that frequent exposure to visible light spectrum of the selfie flashes may cause skin damage and accelerated skin ageing. In this paper we have addressed the different aspects of potential effects of exposure to the light emitted from smartphones’ digital screens as well as smartphones’ photoflashes on premature aging of the human skin. Specifically, the effects of blue light on eyes and skin are discussed. Based on current knowledge, it can be suggested that changing the spectral output of LED-based smartphones’ flashes can be introduced as an effective method to reduce the adverse health effects associated with exposure to blue light.

Circadian rhythm and fast responses to blue light of photosynthesis in Ectocarpus (Phaeophyta, Ectocarpales)

Planta ◽  
1992 ◽  
Vol 187 (1) ◽  
pp. 60-66 ◽  
Author(s):  
Rainer Schmid ◽  
Rodney Forster ◽  
Matthew J. Dring
Keyword(s):  
Circadian Rhythm ◽  
Blue Light ◽  
Fast Responses

scholarly journals Age Associated Decrease of MT-1 Melatonin Receptor in Human Dermal Skin Fibroblasts Impairs Protection Against UV-Induced DNA Damage

2020 ◽  
Vol 21 (1) ◽  
pp. 326
Author(s):  
Kelly Dong ◽  
Earl Goyarts ◽  
Antonella Rella ◽  
Edward Pelle ◽  
Yung Hou Wong ◽  
...  
Keyword(s):  
Dna Damage ◽  
Circadian Rhythm ◽  
Human Skin ◽  
Human Body ◽  
Skin Aging ◽  
Skin Fibroblasts ◽  
Melatonin Receptor ◽  
Skin Cells ◽  
Normal Human

The human body follows a physiological rhythm in response to the day/night cycle which is synchronized with the circadian rhythm through internal clocks. Most cells in the human body, including skin cells, express autonomous clocks and the genes responsible for running those clocks. Melatonin, a ubiquitous small molecular weight hormone, is critical in regulating the sleep cycle and other functions in the body. Melatonin is present in the skin and, in this study, we showed that it has the ability to dose-dependently stimulate PER1 clock gene expression in normal human dermal fibroblasts and normal human epidermal keratinocytes. Then we further evaluated the role of MT-1 melatonin receptor in mediating melatonin actions on human skin using fibroblasts derived from young and old subjects. Using immunocytochemistry, Western blotting and RT-PCR, we confirmed the expression of MT-1 receptor in human skin fibroblasts and demonstrated a dramatic age-dependent decrease in its level in mature fibroblasts. We used siRNA technology to transiently knockdown MT-1 receptor in fibroblasts. In these MT-1 knockdown cells, UV-dependent oxidative stress (H2O2 production) was enhanced and DNA damage was also increased, suggesting a critical role of MT-1 receptor in protecting skin cells from UV-induced DNA damage. These studies demonstrate that the melatonin pathway plays a pivotal role in skin aging and damage. Moreover, its correlation with skin circadian rhythm may offer new approaches for decelerating skin aging by modulating the expression of melatonin receptors in human skin.

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