Demodex folliculorum: its association with oily skin surface rather than rosacea lesions

2014 ◽  
Vol 54 (1) ◽  
pp. e14-e17 ◽  
Author(s):  
Carlos A. Porta Guardia
Keyword(s):  
Skin Surface ◽  
Demodex Folliculorum

scholarly journals Role of Adenosine Deaminase in Patients with Erythematotelan-giectatic Rosacea and Demodex folliculorum Positivity

2020 ◽  
Author(s):  
Serpil SENER ◽  
Ulku KARAMAN ◽  
Tugba Raika KIRAN ◽  
Cemil COLAK ◽  
Ali ASLAN ◽  
...  
Keyword(s):  
Adenosine Deaminase ◽  
Close Contact ◽  
Acne Vulgaris ◽  
Skin Surface ◽  
Control Group ◽  
Purine Nucleotides ◽  
Demodex Folliculorum ◽  
Significant Difference ◽  
The Mean ◽  
And Gender

Background: Adenosine deaminase (ADA) is an aminohydrolase involved in the catabolism of purine nucleotides and irreversibly deaminizes adenosine and deoxyadenosine to inosine and deoxyinosine. ADA enzyme deficiency results in the loss of functional properties of B and T lymphocytes. Demodex species have been reported to be transmitted between humans through close contact and to play a role in the pathogenesis of rosacea, acne vulgaris, perioral dermatitis, seborrhoeic dermatitis, micropapillary-pruritic dermatitis and blepharitis. The present study aimed to compare serum ADA levels in D. folliculorum positive patients with the healthy control individuals. Methods: Serum ADA levels were examined for 30 patients diagnosed with erythematotelangiectatic rosacea and 40 healthy individuals in Malatya Inonu University in 2017. Standardized skin surface biopsy (SSSB) method was used to diagnose D. folliculorum. A significant decrease was found in the ADA levels of Demodex-positive rosacea patients when compared to the control group. Results: ADA levels were decreased in the Demodex-positive group. The mean ADA level in patient group was significantly lower than the mean in the control group (P<0.001). There was no significant difference between the patient and control groups in terms of age and gender. Conclusion: During and after treatment of Demodex-positive rosacea patients, determination of ADA levels may give more detailed information on the immune mechanisms.

Demodex folliculorum and topical treatment: acaricidal action evaluated by standardized skin surface biopsy

1998 ◽  
Vol 138 (3) ◽  
pp. 461-466 ◽  
Author(s):  
Forton ◽  
Seys ◽  
Marchal ◽  
Song
Keyword(s):  
Topical Treatment ◽  
Skin Surface ◽  
Demodex Folliculorum

Demodex folliculorum in rosacea based on a modified standardized skin surface biopsy

2015 ◽  
Vol 28 (3) ◽  
pp. 177-180 ◽  
Author(s):  
Hubert Arasiewicz ◽  
Piotr Szilman ◽  
Ligia Brzezińska-Wcisło
Keyword(s):  
Skin Surface ◽  
Demodex Folliculorum

scholarly journals The presence of the parasite Demodex folliculorum on the skin surface of the eyelid

1991 ◽  
Vol 19 (3) ◽  
pp. 229-234 ◽  
Author(s):  
Frank P. English ◽  
Guang Wen Zhang ◽  
Don P. McManus ◽  
Felicity A. Home
Keyword(s):  
Skin Surface ◽  
Demodex Folliculorum

scholarly journals Scale and Pustule on Dermoscopy of Rosacea: A Diagnostic Clue for Demodex Species

2021 ◽  
pp. e2021139
Author(s):  
Gamze Serarslan ◽  
Özlem Makbule Kaya ◽  
Emre Dirican
Keyword(s):  
Sensitivity And Specificity ◽  
Skin Surface ◽  
Noninvasive Diagnosis ◽  
Healthy Skin ◽  
Dermatological Diseases ◽  
Demodex Folliculorum ◽  
Demodex Brevis ◽  
Dermoscopic Image ◽  
Diagnostic Clue ◽  
Demodex Mites

Background: Demodex mites are highly found in the skin of patients with rosacea.The diagnosis of Demodex can be made by standardized skin surface biopsy. Dermoscopy is a tool used in the noninvasive diagnosis of various dermatological diseases. Objectives: To determine whether dermoscopic features of demodicosis are associated with the result of standardized skin surface biopsy in patients with rosacea and to compare dermoscopic features of rosacea in Demodex-positive and negative samples and Demodex type. Methods: A total of 30 patients (7 male, 23 female) were included in the study. Dermoscopic examination was performed on both the clinically most severely affected areas and adjacent healthy skin. The skin surface biopsy sample was taken from the same place from where the dermoscopic image was taken. Results: A total of 83 (lesion n = 60, non-lesion n = 23) areas were evaluated. Demodex was detected in 60.2% (n = 50) of the samples. Half of these samples revealed only Demodex folliculorum, and the remaining half revealed D folliculorum and Demodex brevis. Of theDemodex-positive samples, 88% had Demodex tails (P =0.001) and68% Demodex follicular openings (P = 0.002) on dermoscopy. In D folliculorum+D brevis-positive samples, the rate of scale and pustule was higher than D folliculorum-positive samples (P = 0.017 and P = 0032,respectively). Conclusions: The sensitivity and specificity of Demodex tail are higher than Demodex follicular opening and scale and pustule detection with dermoscopy and may indicate the coexistence of both D folliculorum and D brevis.

Studies on Demodex folliculorum Simon (1842). I. Life history

Parasitology ◽  
1961 ◽  
Vol 51 (1-2) ◽  
pp. 181-192 ◽  
Author(s):  
S. G. Spickett
Keyword(s):  
Life History ◽  
Life Cycle ◽  
Life Span ◽  
Statistical Methods ◽  
Skin Surface ◽  
Birkbeck College ◽  
Demodex Folliculorum ◽  
Histological Data ◽  
History Of

1. Histological data are given about the location and frequency of the different stages of the life history of D. folliculorum in the pilo-sebaceous apparatus of man. These data are examined statistically and the relative durations of each stage and their movements in the follicle are deduced from them.2. A method of in vitro culture is described and data are given about the longevity of the various stages of the life history.3. Experiments on the behaviour of the different motile stages of the mite are described. It is concluded that the deutonymph is the distributive stage, and that distribution occurs over the skin surface.4. The life history is reconstructed by a synthesis of the evidence presented. The life-cycle lasts approximately 14½ days, the life span of each stage of it being: ovum 60 hr., larva 36 hr., protonymph 72 hr., deutonymph 60 hr., adult 120 hr. Interval between copulation and oviposition 12 hr.This work was largely carried out in the Department of Pathology of the Institute of Dermatology, London, and I wish to thank the Director of Pathology, Dr J. O. Oliver, for making available to me the facilities of his department, and for his advice and interest during the progress of the work. The photographs were prepared by Mr R. H. Lunnan of the Photographic Department of the Institute of Dermatology. I am indebted to the Dean of the Institute of Dermatology for permission to publish the photographs.I am grateful to Mr T. E. Hughes of the Department of Zoology, Birkbeck College, University of London, for his advice at all times, and to Miss Hilda Davies of the Department of Statistics, University of Sheffield, for help with statistical methods and to Mr W. Moseley, who prepared the text figures.Finally, I wish to express my thanks to Professor I. Chester Jones and Dr E. T. B. Francis of the Department of Zoology, University of Sheffield, for reading the manuscript and for their help in its preparation.

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