Low-dose oral isotretinoin therapy in lichen planus pigmentosus: an open-label non-randomized prospective pilot study

2016 ◽  
Vol 55 (9) ◽  
pp. 1048-1054 ◽  
Author(s):  
Sendhil Kumaran Muthu ◽  
Tarun Narang ◽  
Uma N. Saikia ◽  
Amrinder Jit Kanwar ◽  
Davinder Parsad ◽  
...  
2019 ◽  
Vol 36 (6) ◽  
pp. 980-981 ◽  
Author(s):  
Nuria Rodriguez‐Garijo ◽  
Elena Querol‐Cisneros ◽  
Alejandra Tomas‐Velazquez ◽  
Angela Estenaga ◽  
Ester Moreno‐Artero ◽  
...  
Keyword(s):  
Low Dose ◽  

Author(s):  
Rashmi Jindal ◽  
Samarjit Roy ◽  
Akanksha Jain

<p class="abstract"><strong>Background:</strong> Oral isotretinoin and azithromycin are two important drugs used in management of acne. Their mode of action is different and thus theoretically the combination of these two should have a synergistic effect.</p><p class="abstract"><strong>Methods:</strong> In this randomized comparative trial 100 patients were randomized into two groups. One received oral isotretinoin (0.3 mg/kg/day) alone and the other group received pulsed azithromycin (500 mg/day for three days in a week for 8 weeks) in addition to oral isotretinoin. Improvement in acne was noted as percentage improvement in mean acne score.<strong></strong></p><p class="abstract"><strong>Results:</strong> No statistically significant difference was noted in the improvement in mean acne score of both the groups.</p><p><strong>Conclusions:</strong> Addition of pulsed azithromycin to low dose oral isotretinoin does not offer a better treatment outcome in patients of moderate to severe acne. </p>


Author(s):  
Federica FILIPPI ◽  
Laura VOLLONO ◽  
Bianca M. PIRACCINI ◽  
Cosimo MISCIALI ◽  
Federico TARTARI ◽  
...  
Keyword(s):  
Low Dose ◽  

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