Oral lichenoid lesions as a sign of Good’s syndrome

2021 ◽  
Author(s):  
Mar Luque‐Luna ◽  
Francesc Alamon‐Reig ◽  
Pilar Iranzo‐Fernández
Keyword(s):  
Good’S Syndrome ◽  
Oral Lichenoid Lesions

scholarly journals Inter-Observer and Intra-Observer Variations in the Assessment of Epithelial Dysplasia in Oral Lichenoid Diseases

2021 ◽  
Vol 8 (2) ◽  
pp. 84-88
Author(s):  
Marwa Zohdy ◽  
Simone Cazzaniga ◽  
Helga Nievergelt ◽  
Roland Blum ◽  
Valérie G. A. Suter ◽  
...  
Keyword(s):  
Lichen Planus ◽  
Oral Lichen Planus ◽  
Epithelial Dysplasia ◽  
Observer Variability ◽  
Oral Lichenoid Lesions ◽  
Inter Observer Variability ◽  
Oral Lichen

Oral lichen planus (OLP) and oral lichenoid lesions (OLL) can both present with histological dysplasia. Despite the presence of WHO-defined criteria for the evaluation of epithelial dysplasia, its assessment is frequently subjective (inter-observer variability). The lack of reproducibility in the evaluation of dysplasia is even more complex in the presence of a lichenoid inflammation. We evaluated dysplasia in 112 oral biopsies with lichenoid inflammation in order to study the inter-observer and the intra-observer variability.

A case report of oral lichenoid lesions related to cross‐reactivity between nickel and palladium

2021 ◽  
Author(s):  
Fumihiko Tsushima ◽  
Jinkyo Sakurai ◽  
Risa Shimizu ◽  
Hiroyuki Harada
Keyword(s):  
Case Report ◽  
Cross Reactivity ◽  
Oral Lichenoid Lesions

The importance of understanding the terminology on oral lichenoid lesions for future research: in reply

Oral Oncology ◽  
2021 ◽  
Vol 117 ◽  
pp. 105282
Author(s):  
Miguel Ángel González-Moles ◽  
Pablo Ramos-García ◽  
Saman Warnakulasuriya
Keyword(s):  
Future Research ◽  
Oral Lichenoid Lesions

scholarly journals Variable clinical characteristics and laboratory results in five patients with Chinese Good's syndrome (thymoma and hypogammaglobulinemia): an 8-year retrospective analysis in a university hospital in China

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Jinyao Ni ◽  
Junwu Zhang ◽  
Yanxia Chen ◽  
Weizhong Wang ◽  
Jinlin Liu
Keyword(s):  
Information System ◽  
Lichen Planus ◽  
Hospital Information System ◽  
Clinical Characteristics ◽  
Opportunistic Infections ◽  
Clinical Symptoms ◽  
University Hospital ◽  
Ivig Treatment ◽  
Good’S Syndrome ◽  
Laboratory Results

Abstract Background Good's syndrome (GS) is a rare secondary immunodeficiency disease presenting as thymoma and hypogammaglobulinemia. Due to its rarity, the diagnosis of GS is often missed. Methods We used the hospital information system to retrospectively screen thymoma and hypogammaglobulinemia patients at the First Affiliated Hospital of Wenzhou Medical University from Apr 2012 to Apr 2020. The clinical, laboratory, treatment, and outcome data for these patients were collected and analyzed. Results Among the 181 screened thymoma patients, 5 thymoma patients with hypogammaglobulinemia were identified; 3 patients had confirmed diagnoses of GS, and the other 2 did not have a diagnosis of GS recorded in the hospital information system. A retrospective review of the clinical characteristics, laboratory results, and follow-up data for these 2 undiagnosed patients confirmed the diagnosis of GS. All 5 GS patients presented with pneumonia, 2 patients presented with recurrent skin abscesses, 2 patients presented with recurrent cough and expectoration, 1 patient presented with recurrent oral lichen planus and diarrhea, and 1 patient presented with tuberculosis and granulomatous epididymitis. In the years after the diagnosis of hypogammaglobulinemia with mild symptoms, all 5 patients had received irregular intravenous immunoglobulin (IVIG) treatment. As the course of the disease progressed, the clinical symptoms of all patients worsened, but the symptoms were partly resolved with IVIG in these patients. However, 4 patients died due to comorbidities. Conclusion GS should be investigated as a possible diagnosis in thymoma patients who present with hypogammaglobulinemia, especially those with recurrent opportunistic infections, recurrent skin abscesses, chronic diarrhea, or recurrent lichen planus.

scholarly journals Allopurinol-Induced Oral Lichenoid Drug Reaction with Complete Regression after Drug Withdrawal

2020 ◽  
Vol 7 (2) ◽  
pp. 18-25
Author(s):  
Alexandre Perez ◽  
Benjamin Lazzarotto ◽  
Jean-Pierre Carrel ◽  
Tommaso Lombardi
Keyword(s):  
Drug Reaction ◽  
Lichen Planus ◽  
Drug Withdrawal ◽  
Acute Onset ◽  
Complete Regression ◽  
Oral Manifestations ◽  
First Line ◽  
Drug Induced ◽  
Case Presentation ◽  
Oral Lichenoid Lesions

Background: Lichen planus is a chronic mucocutaneous inflammatory disease. Oral manifestations are common, and may remain exclusive to the oral mucosa without involvement of the skin or other mucosae. A differential diagnosis includes oral lichenoid drug reactions. Allopurinol, which is the first line hypo-uricemic treatment, is often quoted as being a possible offending drug, though oral reactions have rarely been reported. Case presentation: We describe a 59-year-old male gout patient, successfully treated with allopurinol, who developed acute onset of oral lichenoid lesions, involving bilaterally the buccal mucosa, the tongue and the labial mucosa. Histopathology was consistent with a lichen planus or a drug-induced lichenoid reaction. Improvement of the patient’s condition after withdrawal of allopurinol confirmed the lichenoid nature of the lesion. Remission was complete after a few weeks. Discussion: Although unusual, allopurinol may induce a lichenoid drug reaction. These reactions may mimic clinically and histopathologically idiopathic lichen planus. Improvement or complete regression of the lesions may be attempted to confirm the diagnosis. According to the latest WHO recommendations, these lesions have a potential for malignant transformation.

Good's syndrome : A case with recurrent respiratory infections

2013 ◽  
Vol 24 ◽  
pp. e143
Author(s):  
S. Ersan ◽  
G. Ersan ◽  
C. Arslan ◽  
S. Atalay ◽  
S. Kose
Keyword(s):  
Respiratory Infections ◽  
Good’S Syndrome ◽  
Recurrent Respiratory Infections

scholarly journals Good's syndrome: First case report in Algeria

2013 ◽  
Vol 4 ◽  
Author(s):  
Messaoudani Nesrine ◽  
Djidjik Reda ◽  
Baough Leila ◽  
Nekhla Ahmed ◽  
Benserai Fatma Zohra ◽  
...  
Keyword(s):  
Case Report ◽  
Good’S Syndrome ◽  
First Case
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