scholarly journals Examination of the relationship between disease activity and patient-reported outcome measures in an inflammatory bowel disease cohort

2018 ◽  
Vol 48 (10) ◽  
pp. 1234-1241 ◽  
Author(s):  
Belinda D. Jackson ◽  
Danny Con ◽  
Alexandra Gorelik ◽  
Danny Liew ◽  
Simon Knowles ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Disease Activity ◽  
Outcome Measures ◽  
Bowel Disease ◽  
Patient Reported Outcome Measures ◽  
Patient Reported Outcome ◽  
Patient Reported ◽  
Inflammatory Bowel ◽  
The Relationship

scholarly journals Patient-Reported Outcome Measures in Inflammatory Bowel Disease

2014 ◽  
Vol 28 (10) ◽  
pp. 536-542 ◽  
Author(s):  
Wael El-Matary
Keyword(s):  
Inflammatory Bowel Disease ◽  
Outcome Measures ◽  
Bowel Disease ◽  
Patient Reported Outcome Measures ◽  
Patient Reported Outcome ◽  
Patient Reported ◽  
United States Food ◽  
Recent Developments ◽  
Inflammatory Bowel ◽  
States Food

Patient-reported outcome measures (PROMs) are increasingly used in both research and clinical health settings. With the recent development of United States Food and Drug Administration guidance on PROMs, more attention is being devoted to their role and importance in health care. Several methodological challenges in the development, validation and implementation of PROMs must be resolved to ensure their appropriate utilization and interpretation. The present review discusses recent developments and updates in PROMs, with specific focus on the area of inflammatory bowel disease.

scholarly journals Correlation of Patient-Reported Outcome (PRO-2) with Endoscopic and Histological Features in Ulcerative Colitis and Crohn’s Disease Patients

2020 ◽  
Vol 2020 ◽  
pp. 1-6
Author(s):  
Sanja Dragasevic ◽  
Aleksandra Sokic-Milutinovic ◽  
Milica Stojkovic Lalosevic ◽  
Tamara Milovanovic ◽  
Srdjan Djuranovic ◽  
...  
Keyword(s):  
Ulcerative Colitis ◽  
Inflammatory Bowel Disease ◽  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Disease Activity ◽  
Bowel Disease ◽  
Scoring System ◽  
Patient Reported Outcome ◽  
Patient Reported ◽  
Inflammatory Bowel

Background and Objectives. Determination of inflammatory bowel disease activity determines further therapeutic approach and follow-up. The aim of our study was to investigate correlation between patients’ reported symptoms and endoscopic and histological disease activity. Methods. A cross-sectional study was conducted in consecutive newly diagnosed patients with inflammatory bowel disease in a tertiary care referral center. The initial evaluation included patient-reported outcome for stool frequency subscore and rectal bleeding. Endoscopic activity was determined using the Mayo scoring system for ulcerative colitis and the Simple Endoscopic Score for Crohn’s disease. Histopathological activity was assessed using a validated numeric scoring system. Results. We included 159 patients (63 Crohn’s disease with colonic involvement and 96 with ulcerative colitis). We found significant correlation between the Mayo endoscopic subscoring system and histology activity in ulcerative colitis, while no correlation was found in patients with Crohn’s disease. Patient-reported outcome showed inverse correlation with endoscopic and histological activity in Crohn’s disease (rs=−0.67; rs=−0.72), while positive correlation was found in ulcerative colitis (rs=0.84; rs=0.75). Interpretation and Conclusions. Patient-reported outcome is a practical and noninvasive tool for assessment of disease activity in ulcerative colitis patients but not in Crohn’s disease.

Sign in / Sign up

Export Citation Format

Share Document