Three‐year follow up of adrenal incidentalomas in a New Zealand centre

2020 ◽  
Vol 50 (3) ◽  
pp. 350-356 ◽  
Author(s):  
Ziwei Goh ◽  
Ian Phillips ◽  
Penny J. Hunt ◽  
Steven Soule ◽  
Tom J. Cawood
Keyword(s):  
New Zealand ◽  
Adrenal Incidentalomas

Eine Therapie mit Everolimus und reduziertem Ciclosporin kann das Krebsrisiko von Nierentransplantierten verringern* (Sponsor: Novartis Pharma GmbH, Nürnberg)

2017 ◽  
Vol 05 (01) ◽  
pp. 22-22
Keyword(s):  
New Zealand ◽  
De Novo

ZusammenfassungDie Verknüpfung der A2309-Studie mit dem Australia and New Zealand Dialysis and Transplant (ANZDATA) Register erlaubte ein Follow up von 7 Jahren. Die Autoren bezeichnen diese Analyse als die bisher überzeugendste Evidenz, dass eine Immunsuppression mit de novo Everolimus und reduziertem Ciclosporin langfristig mit einer geringeren Krebsinzidenz nach Nierentransplantation assoziiert ist als die Standardtherapie.

scholarly journals Aspirin treatment prevents inflammation in experimental bifurcation aneurysms in New Zealand White rabbits

2021 ◽  
pp. neurintsurg-2020-017261
Author(s):  
Stefan Wanderer ◽  
Basil Erwin Grüter ◽  
Fabio Strange ◽  
Gwendoline Boillat ◽  
Sivani Sivanrupan ◽  
...  
Keyword(s):  
New Zealand ◽  
Clinical Situation ◽  
Fluorescence Angiography ◽  
Preventive Effect ◽  
Aneurysm Formation ◽  
Aneurysm Wall ◽  
New Zealand White Rabbits ◽  
Aneurysm Thrombosis ◽  
Wall Groups

BackgroundAneurysm wall degeneration is linked to growth and rupture. To address the effect of aspirin (ASA) on aneurysm formation under various wall conditions, this issue was analyzed in a novel rabbit bifurcation model.MethodsBifurcation aneurysms created in 45 New Zealand White rabbits were randomized to vital (n=15), decellularized (n=13), or elastase-degraded (n=17) wall groups; each group was assigned to a study arm with or without ASA. At follow-up 28 days later, aneurysms were evaluated for patency, growth, and wall inflammation at macroscopic and histological levels.Results36 rabbits survived to follow-up at the end of the trial. None of the aneurysms had ruptured. Patency was visualized in all aneurysms by intraoperative fluorescence angiography and confirmed in 33 (92%) of 36 aneurysms by MRI/MRA. Aneurysm size was significantly increased in the vital (without ASA) and elastase-degraded (with and without ASA) groups. Aneurysm thrombosis was considered complete in three (50%) of six decellularized aneurysms without ASA by MRI/MRA. Locoregional inflammation of the aneurysm complex was significantly reduced in histological analysis among all groups treated with ASA.ConclusionASA intake prevented inflammation of both the periadventitial tissue and aneurysm wall, irrespective of initial wall condition. Although ASA prevented significant growth in aneurysms with vital walls, this preventive effect did not have an important role in elastase-degraded pouches. In possible translation to the clinical situation, ASA might exert a potential preventive effect during early phases of aneurysm formation in patients with healthy vessels but not in those with highly degenerative aneurysm walls.

Potroom asthma: New Zealand experience and follow-up

1989 ◽  
Vol 15 (1) ◽  
pp. 43-49 ◽  
Author(s):  
T. V. O'Donnell ◽  
B. Welford ◽  
E. D. Coleman
Keyword(s):  
New Zealand

Adrenal Incidentalomas: Diagnostic Evaluation and Long-Term Follow-Up

2008 ◽  
Vol 14 (3) ◽  
pp. 269-278
Author(s):  
Lucio Vilar ◽  
Maria da Conceição Freitas ◽  
Viviane Canadas ◽  
José Luciano Albuquerque ◽  
Carlos A. Botelho ◽  
...  
Keyword(s):  
Diagnostic Evaluation ◽  
Adrenal Incidentalomas ◽  
Long Term Follow Up

Wi-Fi Deployment in Large New Zealand Organizations

2007 ◽  
pp. 24-271
Author(s):  
Bryan Houliston ◽  
Nurul Sarkar
Keyword(s):  
Wireless Networks ◽  
New Zealand ◽  
Case Studies ◽  
Low Cost ◽  
Local Area Networks ◽  
Local Area ◽  
Wireless Local Area Networks ◽  
User Mobility ◽  
Ieee 802.11B

Wi-Fi (also known as IEEE 802.11b) networks are gaining widespread popularity as wireless local area networks (WLANs) due to their simplicity in operation, robustness, low cost, and user mobility offered by the technology. It is a viable technology for wireless local area networking applications in both business and home environments. This chapter reports on a survey of large New Zealand organizations focusing on the level of Wi-Fi deployment, reasons for non-deployment, the scope of deployment, investment in deployment, problems encountered, and future plans. Our findings show that most organizations have at least considered the technology, though a much smaller proportion has deployed it on any significant scale. A follow up review of the latest published case studies and surveys suggests that while Wi-Fi networks are consolidating, interest is growing in wider area wireless networks.

scholarly journals Chemical Dependence in Anaesthetic Registrars in Australia and New Zealand

1993 ◽  
Vol 21 (2) ◽  
pp. 151-155 ◽  
Author(s):  
A. M. Weeks ◽  
M. R. Buckland ◽  
E. B. Morgan ◽  
P. S. Myles
Keyword(s):  
New Zealand ◽  
Health Problem ◽  
Chemical Dependence ◽  
Chemically Dependent ◽  
Major Health Problem ◽  
Major Health

The Supervisors of Anaesthetic Training in Australia and New Zealand were surveyed and asked to report any cases of chemical dependence from anaesthetic registrars at their hospital from 1981 to 1991. From 83 questionnaires there were 65 (78%) returned. There were 14 departments (22%) with experience of one or more cases during this interval. Only five (7%) reported conducting a lecture or tutorial on the problem. The departmental reports covered 4425 registrar years of training and there were 17 cases reported. Of these, 13 were complete and are considered in detail. It is estimated that 1.3 % of those who entered anaesthetic training during the interval were recognised to become chemically dependent during their training. Follow-up was available on only six of the 13 registrars and only one was reported to have completed training. The results of this survey indicate that chemical dependence is already a major health problem amongst anaesthetic registrars in Australia and New Zealand.

scholarly journals Quality of prescribing predicts hospitalisation in octogenarians: life and living in advanced age: a cohort study in New Zealand (LiLACS NZ)

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Cristín Ryan ◽  
Ruth Teh ◽  
Simon Moyes ◽  
Tim Wilkinson ◽  
Martin Connolly ◽  
...  
Keyword(s):  
Cohort Study ◽  
New Zealand ◽  
Inappropriate Prescribing ◽  
Advanced Age ◽  
Medical Conditions ◽  
Potentially Inappropriate Medicines ◽  
Prescribing Omissions ◽  
Potential Prescribing Omissions

Abstract Background Prescribing for older people is complex, and many studies have highlighted that appropriate prescribing in this cohort is not always achieved. However, the long-term effect of inappropriate prescribing on outcomes such as hospitalisation and mortality has not been demonstrated. The aim of this study was to determine the level of potentially inappropriate prescribing (PIP) for participants of the Life and Living in Advanced Age: A Cohort Study in New Zealand (LiLACS NZ) study at baseline and examine the association between PIP and hospitalisation and mortality at 12-months follow-up. Methods PIP was determined using STOPP/START. STOPP identified potentially inappropriate medicines (PIMs) prescribed, START identified potential prescribing omissions (PPOs). STOPP/START were applied to all LiLACS NZ study participants, a longitudinal study of ageing, which includes 421 Māori aged 80–90 years and 516 non-Māori aged 85 years. Participants’ details (e.g. age, sex, living arrangements, socioeconomic status, physical functioning, medical conditions) were gathered by trained interviewers. Some participants completed a core questionnaire only, which did not include medications details. Medical conditions were established from a combination of self-report, review of hospital discharge and general practitioner records. Binary logistic regression, controlled for multiple potential confounders, was conducted to determine if either PIMs or PPOs were associated with hospital admissions and mortality (p < 0.05 was considered significant). Results Full data were obtained for 267 Māori and 404 non-Māori. The mean age for Māori was 82.3(±2.6) years, and 84.6(±0.53) years for non-Māori. 247 potentially inappropriate medicines were identified, affecting 24.3% Māori and 28.0% non-Māori. PIMs were not associated with 12-month mortality or hospitalisation for either cohort (p > 0.05; adjusted models). 590 potential prescribing omissions were identified, affecting 58.1% Māori and 49.0% non-Māori. PPOs were associated with hospitalisation (p = 0.001 for Māori), but were not associated with risk of mortality (p > 0.05) for either cohort within the 12-month follow-up (adjusted models). Conclusion PPOs were more common than PIMs and were associated with an increased risk of hospitalisation for Māori. This study highlights the importance of carefully considering all indicated medicines when deciding what to prescribe. Further follow-up is necessary to determine the long-term effects of PIP on mortality and hospitalisation.

Long-term morphological, hormonal, and clinical follow-up in a single unit on 118 patients with adrenal incidentalomas

2010 ◽  
Vol 162 (4) ◽  
pp. 779-785 ◽  
Author(s):  
R Giordano ◽  
E Marinazzo ◽  
R Berardelli ◽  
A Picu ◽  
M Maccario ◽  
...  
Keyword(s):  
Cushing’S Syndrome ◽  
Cumulative Risk ◽  
Cushing's Syndrome ◽  
Endocrine Function ◽  
Adrenal Incidentalomas ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Significant Clinical Improvement

ObjectiveTo evaluate long-term morphological, functional, and clinical outcome in adrenal incidentalomas.Design and methodsA total of 118 patients (77 F and 47 M; age 62.3±1.0 years) with adrenal incidentalomas were evaluated at baseline and followed-up for median 3 years (range 1–10 years) by clinical, biochemical, hormonal, and morphological evaluation. Among them, six patients with diagnosis of subclinical Cushing's syndrome (SCS) underwent surgery.ResultsAt entry, 86% (n=102) of tumors were nonfunctioning (NF) and 14% (n=16) showed SCS. Comparing NF with SCS patients, a significantly higher percentage of dyslipidemia was found in the group of SCS patients (50 vs 23%,P=0.033). During follow-up, adrenal function remained normal in all NF patients, none of them developed subclinical or overt endocrine disease. The cumulative risk of mass enlargement was globally low (25%), but progressive up to 8 years. SCS was confirmed in all patients, and none of them shifted to overt Cushing's syndrome. The cumulative risk of developing metabolic–cardiovascular abnormalities was globally low (22%), but progressive up to 8 years and new diseases were recorded in the group of NF patients only (three patients with dyslipidemia, four with impaired fasting glucose/impaired glucose tolerance, and three with diabetes mellitus). SCS patients who underwent surgery did not show any significant clinical improvement.ConclusionsThe risk of mass enlargement, hormonal, and metabolic impairment over time is globally low. Conservative management seems to be appropriate, but further prospective studies are needed to establish the long-term outcome of such patients, especially for metabolic status, cardiovascular risk profile and their relationship with endocrine function.

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