Diagnostic challenge of Q fever osteoarticular infection

2021 ◽  
Vol 51 (1) ◽  
pp. 142-143
Author(s):  
Beatrice Z. Sim ◽  
Luke Aaron ◽  
Bernice L. Sim ◽  
David Looke ◽  
Evan Bursle
2020 ◽  
Vol 26 (9) ◽  
Author(s):  
Halima Dabaja-Younis ◽  
Michal Meir ◽  
Anat Ilivizki ◽  
Daniela Militianu ◽  
Mark Eidelman ◽  
...  

Author(s):  
Denisse Espinosa-Encalada ◽  
Sergio Copete Piqueras ◽  
Alfonso Gómez Cortés ◽  
Cristina Isabel Blanco Marchite

2021 ◽  
Vol 14 (7) ◽  
pp. e243743
Author(s):  
Torcato Moreira Marques ◽  
Lourenço Cruz ◽  
Raquel Soares ◽  
Sofia Eusébio

A 79-year-old man was admitted to our ward with symptomatic heart failure 2 months after aortic valve replacement due to severe aortic stenosis. On the third day following admission, he became febrile (>38°C) while manifesting an increase in inflammatory markers. Endocarditis was suspected despite negative blood cultures. Echocardiogram (transthoracic and transesophageal) did not describe any vegetations. No hypermetabolic lesions were described on the Positron emission tomography scan. Empirical antibiotics were started but the fever persisted. Serologies revealed a Coxiella burnetii IgG phase II titre of 1:800, high erythrocyte sedimentation rate. Positive antinuclear antibodies, antibeta2 IgM and anticardiolipin supported a diagnosis of acute Q fever endocarditis. Doxycycline and hydroxychloroquine were started with total resolution of symptoms. This case illustrates the difficulty of diagnosing Q fever endocarditis during its acute phase, not only because vegetations can be minimal or absent, a challenge that is further compounded by a complex presentation of immunological markers.


2013 ◽  
Vol 6 (1) ◽  
pp. 19-24
Author(s):  
Lee Boon Ang ◽  
Tracy D. Andrews

Acute query (Q) fever caused by Coxiella burnetii infection can present with various signs and symptoms such as flulike illness, pneumonia, or hepatitis, creating a diagnostic challenge. Patients with previous valve surgery are at a higher risk of developing chronic Q fever endocarditis, several months or years following initial infection despite treatment. Q fever was primarily seen in patients who have contact with farm animals. It is being seen in military or contracted personnel returning from Middle East deployment or in close proximity to a farm. The incidence has increased nearly seven times because it became a nationally reported disease in 1999. The Centers for Disease Control and Prevention (CDC) lists C. burnetii as a potential bioterrorism agent caused by its inhalation transmission and bacterial resistance to heat and chemicals. Currently, vaccination is not available in the United States. In Australia, vaccination has resulted in a decrease in prevalence.


Author(s):  
C. Landais ◽  
F. Fenollar ◽  
A. Constantin ◽  
C. Cazorla ◽  
C. Guilyardi ◽  
...  

2018 ◽  
Vol 24 ◽  
pp. 199
Author(s):  
Mumtaheena Miah ◽  
Puspalatha Sajja ◽  
Catherine Anastasopoulou ◽  
Nissa Blocher ◽  
Janna Prater

Sign in / Sign up

Export Citation Format

Share Document