scholarly journals Use of epidermal skin grafts in chronic wounds: a case series

2017 ◽  
Vol 14 (6) ◽  
pp. 1213-1218 ◽  
Author(s):  
Peter AM Everts ◽  
Marco Warbout ◽  
Diana de Veth ◽  
Merel Cirkel ◽  
Nicole E Spruijt ◽  
...  
Keyword(s):  
Chronic Wounds ◽  
Case Series ◽  
Skin Grafts

Deformity and Clinical Outcomes Following Operative Correction of Charcot Ankle

2018 ◽  
Vol 40 (2) ◽  
pp. 145-151 ◽  
Author(s):  
Elizabeth A. Harkin ◽  
Andrew M. Schneider ◽  
Michael Murphy ◽  
Adam P. Schiff ◽  
Michael S. Pinzur
Keyword(s):  
Clinical Outcome ◽  
Clinical Outcomes ◽  
Ankle Joint ◽  
Chronic Wounds ◽  
Surgical Techniques ◽  
Case Series ◽  
Lessons Learned ◽  
Charcot Foot ◽  
Operative Correction ◽  
Therapeutic Footwear

Background: Deformity associated with Charcot foot arthropathy leads to a poor quality of life in affected individuals. Deformity in the midfoot appears to be predictive of clinical outcomes following operative correction. The goal of this retrospective study was to determine if that same methodology could be applied to patients treated for Charcot foot arthropathy involving the ankle joint. Methods: Fifty-six consecutive patients underwent operative reconstruction of Charcot foot deformity involving the ankle joint by a single surgeon over a 14-year period. Preoperative patient characteristics and tibiotalar alignment, were recorded. Surgical treatment included single-stage debridement of active infection and ankle arthrodesis with application of a circular external fixator when infection was present (39 of 56, 69.6%) or retrograde locked intramedullary nailing in the absence of infection (17 of 56, 30.3%). Clinical outcomes were graded based on limb salvage, resolution of infection and chronic wounds, and the ability to ambulate with therapeutic footwear or accommodative orthoses. The average follow-up was 7.5 (range 1.1-14.0) years. Results: One patient died at 134.3 weeks following surgery of unrelated causes and 8 underwent amputation. Twenty-eight of 56 patients (50.0%) achieved a favorable (excellent or good) clinical outcome. There was no significant association between pre- or postoperative alignment and clinical outcomes. Insulin-dependent diabetics were approximately 3 times more likely to have a poor clinical outcome. Conclusions: Operative correction of Charcot deformity involving the ankle joint was associated with a high complication rate and risk for failure. The lessons learned from this highly comorbid patient population with complex deformities can be used as a benchmark for applying modern surgical techniques. Level of Evidence: Level IV, case series.

scholarly journals Treatment of Leg Chronic Wounds with Dermal Substitutes and Thin Skin Grafts

Skin Grafts ◽  
10.5772/51852 ◽  
2013 ◽  
Author(s):  
Silvestro Canonico ◽  
Ferdinando Campitiello ◽  
Angela Della ◽  
Vincenzo Padovano ◽  
Gianluca Pellino
Keyword(s):  
Chronic Wounds ◽  
Skin Grafts ◽  
Dermal Substitutes ◽  
Thin Skin

A histological analysis of chronic wounds treated with negative pressure wound therapy to aid healing: a case series

2018 ◽  
Vol 27 (Sup2) ◽  
pp. S28-S34 ◽  
Author(s):  
Jorge E. Almeida ◽  
Rodolfo Suárez ◽  
Elaine Gibson
Keyword(s):  
Negative Pressure ◽  
Negative Pressure Wound Therapy ◽  
Chronic Wounds ◽  
Histological Analysis ◽  
Case Series ◽  
Wound Therapy

scholarly journals Prontosan® soluzione e Prontosan® Debridement Pad nel trattamento di diversi tipi di ferite cutanee: dichiarazioni basate su opinioni di esperti, serie di casi e revisione della letteratura/Prontosan® solution and Prontosan® Debridement Pad in the treatment of different types of cutaneous wounds: expert-based statements, case series and review of the literature

2019 ◽  
Vol 3 (3) ◽  
Author(s):  
Angela Peghetti ◽  
Diletta Olivari ◽  
Silvia Tedesco ◽  
Andrea Bellingeri ◽  
Marino Ciliberti ◽  
...  
Keyword(s):  
Literature Review ◽  
Chronic Wounds ◽  
Wound Care ◽  
Evidence Synthesis ◽  
New Technology ◽  
Case Series ◽  
Sono State ◽  
Review Of The Literature ◽  
Combined System ◽  
New Device

Prontosan® Debridement Pad (PDP; B. Braun) è un nuovo presidio disegnato per migliorare il processo di debridement meccanico. In questo lavoro riportiamo i risultati di un complesso progetto condotto al fine di sviluppare consenso tra gli esperti sul migliore modo di impiegare questa nuova tecnologia nella pratica clinica. Il progetto si è articolato in tre fasi. Nella prima è stata condotta una estesa revisione della letteratura che ha condotto ad identificare, analizzare criticamente e a riassumere in formato strutturato 27 studi clinici pertinenti. Nella seconda fase le evidenze disponibili sono state discusse in modo sistematico con un pannello di 10 esperti, i quali hanno formulato 12 raccomandazioni per l'impiego clinico del PDP. Queste raccomandazioni sono state quindi sottoposte a votazione formale attraverso il metodo GRADE. Infine, nei mesi successivi, 13 casi clinici provenienti dalla pratica clinica routinaria e trattati in accordo con le raccomandazioni stabilite sono stati raccolti e vengono qui presentati. Nel complesso, i dati disponibili in letteratura e quelli raccolti dalla pratica clinica confermano l'efficacia del PDP come strumento per il debridement meccanico, offrendo vantaggi significativi per una ottimale Wound Bed Preparation e per il controllo del dolore. Il nostro progetto può inoltre essere utile per ottimizzare l'impiego pratico di questo nuovo promettente dispositivo. Prontosan® Debridement Pad (PDP; B. Braun) is a new device designed for mechanical debridement. This paper summarizes the results of a complex initiative aimed to develop consensus among a panel of wound care experts about the optimal use of this new technology. An extensive review of the literature found 27 pertinent papers, which underwent a formal process of critical appraisal and evidence extraction by two independent methodologists. Results are displayed in an evidence report. 12 practical recommendations, concerning management of acute and chronic wounds, have been developed and approved. Main point of strength of this project is the use of a systematic approach to literature review, evidence synthesis and presentation, development and measurement of expert consensus. Moreover, expert panel provided further clinical data, through the reporting of 13 clinical cases managed according to abovementioned recommendations, with a particular focus on burns and chronic ulcers treatment, both in adult and pediatric patients. Overall, results from literature review and from clinical experience confirm that the combined system Prontosan® Solution and PDP is a promising tool useful in the critical phase of debridement in acute and chronic wounds treatment. Efficacy in debris removal and pain reduction are the main points of strength. Our project may contribute to optimize clinical use of this innovative device.

Dehydrated amniotic membrane allografts for the treatment of chronic wounds: a case series

2012 ◽  
Vol 21 (6) ◽  
pp. 290-296 ◽  
Author(s):  
J. Forbes ◽  
D.E. Fetterolf
Keyword(s):  
Amniotic Membrane ◽  
Chronic Wounds ◽  
Case Series

Case Series of Lower-Extremity Chronic Wounds Managed with an Antibacterial Foam Dressing Bound with Gentian Violet and Methylene Blue

2014 ◽  
Vol 27 ◽  
pp. 9-13 ◽  
Author(s):  
Patricia M. Coutts ◽  
Judy Ryan ◽  
R. Gary Sibbald
Keyword(s):  
Methylene Blue ◽  
Lower Extremity ◽  
Chronic Wounds ◽  
Gentian Violet ◽  
Case Series

Potential implications of biofilm in chronic wounds: a case series

2012 ◽  
Vol 21 (3) ◽  
pp. 109-119 ◽  
Author(s):  
J. Hurlow ◽  
P.G. Bowler
Keyword(s):  
Chronic Wounds ◽  
Case Series

Outcomes of Conventional Wound Treatment in a Comprehensive Wound Center

2006 ◽  
Vol 72 (4) ◽  
pp. 314-317 ◽  
Author(s):  
Gabriel Akopian ◽  
Susan P. Nunnery ◽  
Jenny Piangenti ◽  
Pam Rankin ◽  
Chugo Rinoie ◽  
...  
Keyword(s):  
Growth Factor ◽  
Chronic Wounds ◽  
Wound Care ◽  
Case Series ◽  
Wound Treatment ◽  
Care Clinic ◽  
Treatment Type ◽  
Diabetic Wounds ◽  
Human Skin Equivalent ◽  
Growth Factor Treatment

Conventional wound care is the elementary treatment modality for treating chronic wounds. However, early treatment with topical growth factors may be needed for a subset of chronic wounds that fail to heal with good wound care alone. A prospective nonrandomized case series from a single-community outpatient wound care clinic is presented here in an effort to identify the subset of chronic wounds that may require early adjuvant intervention. There were 378 consecutive patients with 774 chronic wounds of varying etiology. All patients received 4 weeks of conventional wound care, including weekly debridement and twice-daily dressing changes. Wounds not reduced by 50 per cent volume at 4 weeks were nonrandomly treated with human skin equivalent (Apligraf®), platelet-derived wound healing factor, or platelet-derived growth factor isoform BB (becaplermin gel, Regranex®). A total of 601 of 774 (78%) wounds healed regardless of treatment type. The median time to heal for all wounds was 49 days (interquartile range = 26–93). More women than men healed (85% vs 71%, respectively, P < 0.0001). Diabetic wounds were as likely to heal as nondiabetic wounds (78% vs 80%, P = 0.5675). Wounds that did not heal had larger volumes and higher grade compared with wounds that healed (P < 0.0001 for both variables). The data presented here show that the majority of chronic wounds will heal with conventional wound care, regardless of etiology. Large wounds with higher grades are less responsive to conventional wound care and will benefit from topical growth factor treatment early in the treatment course.

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