The distribution of ichthyoplankton in Southampton Water in response to low oxygen levels produced by a Mesodinium rubrum bloom

Eukaryotic life depends largely on molecular oxygen. During evolution, ingenious mechanisms have evolved that allow organisms to adapt when oxygen levels decrease. Many of these adaptional responses to low oxygen are orchestrated by the heterodimeric transcription factor hypoxia-inducible factor (HIF). Here, we review the link between HIF and apoptosis.

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Capillary and Venous Blood Glucose Accuracy in Blood Glucose Meters Versus Reference Standards: The Impact of Study Design on Accuracy Evaluations

Journal of Diabetes Science and Technology ◽

10.1177/1932296818790228 ◽

2018 ◽

Vol 13 (3) ◽

pp. 546-552 ◽

Cited By ~ 4

Author(s):

Kirsty Macleod ◽

Laurence B. Katz ◽

Hilary Cameron

Keyword(s):

Blood Glucose ◽

Study Design ◽

Health Care Professionals ◽

Best Practice ◽

Venous Blood ◽

Low Oxygen ◽

Oxygen Levels ◽

Reference Instrument ◽

Venous Sample ◽

The Impact

Background: Anecdotal blood glucose assessments conducted by health care professionals (HCPs) in the field have highlighted differences in results when methodology used is not according to best practices for measuring blood glucose. This study assessed the impact on accuracy of blood glucose measurements when methodology deviates from the recommended study design and recommended reference instrument. Methods: Adults with type 1 or type 2 diabetes provided capillary and venous blood samples for accuracy assessments using OneTouch® Verio® (Verio) and OneTouch® Ultra 2® (Ultra) blood glucose meters (BGM) and two different reference instruments. Results: Increases in mean bias were observed when comparing capillary to venous samples tested on the BGMs and the recommended reference instrument. Mean bias was even greater when a hospital blood glucose analyzer was used to measure venous plasma glucose. Increases in mean bias observed for Ultra BGM when testing venous blood on the meter compared to the recommended reference instrument was likely due to the interfering effects of low oxygen levels in the venous blood sample. Conversely, Verio meters, which are insensitive to low oxygen levels, showed little difference from baseline when testing venous blood on the meter compared to results from the same venous sample measured on a reference instrument. Conclusions: Deviations from the best practice study design of comparing capillary blood glucose results tested on the blood glucose meter with the manufacturer’s stated reference instrument will affect accuracy of blood glucose measurements.

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Foraminiferal paleodiversity and paleoenvironments at the NE coastal plain of Buenos Aires province (Argentina) during the Mid-Holocene sea level highstand

The Holocene ◽

10.1177/0959683620961511 ◽

2020 ◽

Vol 31 (1) ◽

pp. 108-120

Author(s):

Angelica Ballesteros-Prada ◽

Mariel Luengo ◽

Isabel Vilanova ◽

Enrique Fucks ◽

Emiliana Bernasconi

Keyword(s):

Sea Level ◽

Coastal Plain ◽

Gradual Transition ◽

Buenos Aires Province ◽

Paleoenvironmental Reconstruction ◽

Low Oxygen ◽

Oxygen Levels ◽

Sedimentary Deposits ◽

Brackish Environment ◽

Holocene Sea Level

In this investigation, we carried out a Mid-Holocene paleoenvironmental reconstruction based on fossilized benthic foraminifera, retrieved from sedimentary deposits located in Bahía Samborombón coastal plain. A total of 38 species, grouped into 19 genera, were identified. The assemblage, constituted mainly by Buccella peruviana (d’Orbigny), Cribroelphidium poeyanum (d’Orbigny), Ammonia parkinsoniana (d’Orbigny) and Ammonia tepida (Cushman), indicate predominantly abnormal marine conditions, characterized by low oxygen levels between ca. 6880–6640 and 5600–5430 yrs cal. BP. During this interval, a quantitative analysis carried out on the assemblages as well as indexes suggest found three different paleoenvironments. The first one, occurring ca. 6880–6640 yrs cal. BP, was a brackish environment with low oxygenation levels and low bottom energy. Then, ca. 6500–6250 yrs cal. BP, an environment with more marine influence, increased oxygen levels and higher energy prevailed. This higher oxygenation could be related to the flow of seawater into the area during the Mid-Holocene sea-level highstand. The third paleoenvironment developed ca. 5590–5430 yrs cal. BP, was under a gradual transition back to a brackish environment with low oxygen levels as well as low energy.

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