Effects of Glucose on Thyrotrophin-Releasing Hormone, Growth Hormone-Releasing Hormone, Somatostatin and Luteinizing Hormone-Releasing Hormone Release from Rat Hypothalamus in vitro

1989 ◽  
Vol 1 (6) ◽  
pp. 437-441 ◽  
Author(s):  
B. M. Lewis ◽  
C. Dieguez ◽  
J. Ham ◽  
M. D. Page ◽  
F. M. Creagh ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Luteinizing Hormone ◽  
Hormone Release ◽  
Growth Hormone Releasing Hormone ◽  
Thyrotrophin Releasing Hormone ◽  
Luteinizing Hormone Releasing Hormone ◽  
Releasing Hormone ◽  
Rat Hypothalamus

VASOTOCIN RELEASE INTO THE CEREBROSPINAL FLUID OF CATS INDUCED BY LUTEINIZING HORMONE RELEASING HORMONE, THYROTROPHIN RELEASING HORMONE AND GROWTH HORMONE RELEASE-INHIBITING HORMONE

1977 ◽  
Vol 75 (1) ◽  
pp. 175-176 ◽  
Author(s):  
R. GOLDSTEIN ◽  
S. PAVEL
Keyword(s):  
Growth Hormone ◽  
Cerebrospinal Fluid ◽  
Luteinizing Hormone ◽  
Pineal Gland ◽  
Hormone Release ◽  
Growth Hormone Release ◽  
Thyrotrophin Releasing Hormone ◽  
Luteinizing Hormone Releasing Hormone ◽  
Releasing Hormone ◽  
Lh Rh

Institute of Endocrinology, Bucharest, Rumania (Received 29 March 1977) The mammalian pineal gland contains (Pavel, 1965) and synthesizes (Pavel, Goldstein, Ghinea & Calb, 1977) the nonapeptide arginine-vasotocin (AVT). Since luteinizing hormone releasing hormone (LH–RH), thyrotrophin releasing hormone (TRH) and growth hormone release-inhibiting hormone (somatostatin, SRIF) have now been localized not only in the brain, but also in the pineal gland (White, Hedlund, Weber, Rippel, Johnston & Wilber, 1974; Pelletier, Le Clerc, Dube, Labrie, Puviani, Arimura & Schally, 1975), we investigated the effects of these peptides on the release of AVT into the cerebrospinal fluid (CSF) of cats. Intracarotid injections of 0·1 μg LH-RH, TRH (Hoechst, Frankfurt), SRIF (Serono, Rome) or oxytocin (Syntocinon, Sandoz Ltd, Basel) in 0·5 ml saline were given to urethane-anaesthetized male cats weighing 3–4 kg. Controls received an equal volume of saline only. The pineal glands were removed 60 min after the injections, quickly homogenized, and extracted

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