The Heterophile Reaction between Anti-Mouse Thymocyte Sera and Sheep Erythrocytes

2008 ◽  
Vol 2 (2) ◽  
pp. 128-138 ◽  
Author(s):  
B. A. BRADLEY ◽  
A. D. BARNES
Keyword(s):  
Sheep Erythrocytes ◽  
Mouse Thymocyte

Effects of Lysozyme Dimer on Humoral Response to Sheep Erythrocytes in Non-treated and Cyclophosphamide-Immunosuppressed Mice

1997 ◽  
Vol 44 (1-10) ◽  
pp. 591-598
Author(s):  
B. Obminska-Domoradzka ◽  
M. ŚWitala ◽  
J. Dȩbowy ◽  
W. Kiczka ◽  
T. Garbulinski
Keyword(s):  
Humoral Response ◽  
Sheep Erythrocytes ◽  
Immunosuppressed Mice

scholarly journals Amino acid transport in normal and glutathione-deficient sheep erythrocytes

1976 ◽  
Vol 154 (1) ◽  
pp. 43-48 ◽  
Author(s):  
J D Young ◽  
J C Ellory ◽  
E M Tucker
Keyword(s):  
Amino Acids ◽  
Amino Acid ◽  
Amino Acid Transport ◽  
Cell Types ◽  
The Other ◽  
Acid Transport ◽  
Sheep Erythrocytes ◽  
Uptake Rates

1. Uptake rates for 23 amino acids were measured for both normal (high-GSH) and GSH-deficient (low-GSH) erythrocytes from Finnish Landrace sheep. 2. Compared with high-GSH cells, low-GSH cells had a markedly diminished permeability to D-alanine, L-alanine, α-amino-n-butyrate, valine, cysteine, serine, threonine, asparagine, lysine and ornithine. Smaller differences were observed for glycine and proline, whereas uptake of the other amino acids was not significantly different in the two cell types.

Nude mice from homozygous nude parents show smaller PFC responses to sheep erythrocytes than nude mice from heterozygous mothers

Nature ◽  
1976 ◽  
Vol 260 (5546) ◽  
pp. 44-45 ◽  
Author(s):  
MARTHA L. HALE ◽  
EDGAR E. HANNA ◽  
CARL T. HANSEN
Keyword(s):  
Nude Mice ◽  
Sheep Erythrocytes

Role of protein kinases in regulating sheep erythrocyte K-Cl cotransport

1996 ◽  
Vol 271 (1) ◽  
pp. C255-C263 ◽  
Author(s):  
P. W. Flatman ◽  
N. C. Adragna ◽  
P. K. Lauf
Keyword(s):  
Protein Kinases ◽  
Tyrosine Kinases ◽  
Kinase Inhibitor ◽  
Sheep Erythrocyte ◽  
Inhibition Constant ◽  
Calyculin A ◽  
Sheep Erythrocytes ◽  
A 23187 ◽  
Maximal Activation

K-Cl cotransport in sheep erythrocytes can be activated by treatment either with A-23187 and EDTA to reduce concentration of internal ionized Mg [Mg]i) to submicromolar levels, with staurosporine, a potent kinase inhibitor, or with N-ethylmaleimide (NEM). Activation by these maneuvers is prevented and reversed by genistein [inhibition constant (Ki) of 15 microM], which inhibits tyrosine kinases (TK). The related glycosidated compound genistin, which does not inhibit TK, does not inhibit transport, whereas another TK inhibitor, tyrphostin B46, inhibits both basal and stimulated transport (Ki of 28 microM). Cotransport activation by NEM is prevented and reversed by the phosphatase inhibitor, calyculin A, and activation by staurosporine occurs only if cells contain ATP. Increasing [Mg]i inhibits cotransport in the presence of calyculin A whether or not staurosporine is present as well. Our work suggests that genistein inhibits cotransport through a TK and that staurosporine and NEM activate cotransport, probably through inhibition of other kinases, causing stimulation through dephosphorylation of a protein (possibly the transporter itself) be a serine/threonine phosphatase. [Mg]i inhibits cotransport by activating a kinase (concentration for half-maximal activation of 10 microM) that phosphorylates this protein.

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