Young patients with both type 1 diabetes mellitus and asthma have a unique IL-12 and IL-18 secretory pattern

2011 ◽  
Vol 12 (7) ◽  
pp. 596-603 ◽  
Author(s):  
Marianna Rachmiel ◽  
Olga Bloch ◽  
Aviv A. Shaul ◽  
Gilad Ben-Yehudah ◽  
Zvi Bistritzer ◽  
...  
2014 ◽  
Vol 96 (1) ◽  
pp. 71-79 ◽  
Author(s):  
Jianli Niu ◽  
M.G.F. Gilliland ◽  
Zhuqing Jin ◽  
Pappachan E. Kolattukudy ◽  
William H. Hoffman

2019 ◽  
Vol 25 (4) ◽  
pp. 183-187
Author(s):  
Melanie Wielicka ◽  
Jolanta Neubauer-Geryk ◽  
Agnieszka Brandt-Varma ◽  
Małgorzata Myśliwiec ◽  
Leszek Bieniaszewski

HORMONES ◽  
2014 ◽  
Author(s):  
Nektraria Papadopoulou-Marketou ◽  
Chrysanthi Skevaki ◽  
Ioanna Kosteria ◽  
Melpomeni Peppa ◽  
George Chrousos ◽  
...  

2013 ◽  
Vol 20 (3) ◽  
pp. 297-306
Author(s):  
Monica Goia-Socol ◽  
Ileana Duncea ◽  
Gabriela Roman ◽  
Mihai-Andrei Goia-Socol ◽  
Daniel-Corneliu Leucuţa ◽  
...  

Abstract Background and aims: Type 1 diabetes mellitus (T1DM) represents a secondary cause of osteoporosis. Our aim was to determine bone mineral density (BMD) changes in a group of young Romanian adults with T1DM and to analyze the factors related to this disease that could have had an impact on bone mass. Material and Methods: Fifty-two young patients with T1DM were compared to 37 healthy volunteers matched for body mass index (BMI). All subjects had their BMD measured at the hip and lumbar spine. Results: We found no statistically significant differences in BMD between T1DM patients and controls (p=0.618 for lumbar spine, p=0.974 for femoral neck and p=0.883 for total hip). Multiple linear regression models detected BMI (p =0.043), smoking (p=0.001) and milk intake (p=0.004 for lumbar spine) as significant BMD determinants. In contrast, no associations were found between BMD and metabolic control, daily insulin dose or presence of diabetic retinopathy and/or neuropathy. Long diabetes duration was negatively associated with BMD in femoral neck (p=0.012). Conclusions: Although we couldn’t find differences between BMD in T1DM patients and controls, the link between diabetes duration and BMD that we found suggests that even young patients with long standing T1DM should have their BMD measured


Reflection ◽  
2021 ◽  
Vol 11 (1) ◽  
pp. 36-42
Author(s):  
O.V. Kolenko ◽  
◽  
Y.B. Lebedev ◽  
A.Y. Khudyakov ◽  
E.L. Sorokin ◽  
...  

Aim. To investigate the technical difficulties of performing the stages of vitreoretinal surgery, the peculiarities of the surgical technique in young patients with the proliferative stage of diabetic retinopathy (DR). Methods. Twelve patients (12 eyes) with type 1 diabetes mellitus (DM) were selected. Their average age was 26±2 years (from 19 to 30 years). There were 4 men and 8 women. All patients had DM since childhood. Selection criteria: presence of indications for vitreoretinal surgery for proliferative DR, age of patients with type 1 DM not more than 30 years, onset of DM in childhood. Results. Initially, the clinical manifestations of proliferative DR in young people with type 1 DM were distinguished by the severity of neovascular and fibrous growths, a tendency to hemorrhages, and the complexity of preoperative preparation in the form of panretinal laser coagulation, at least partial. Surgical removal of vitreoretinal adhesions and elimination of neovascularization zones differed in technical difficulties associated with their higher density and the area of retinal tissue lesion. Conclusion. Surgical treatment of proliferative DR in young patients has a number of technical difficulties associated with the density and length of fibrovascular vitreoretinal growths, the difficulty of separating them due to the high tendency of newly formed vessels to hemorrhages. Key words: proliferative diabetic retinopathy; endovitreal surgery; type 1 diabetes mellitus; young age.


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