The role of complement in invasive fungal infections. Die Rolle des Komplements bei invasiven Pilzinfektionen

Mycoses ◽  
2004 ◽  
Vol 47 (3-4) ◽  
pp. 93-103 ◽  
Author(s):  
Cornelia Speth ◽  
Gunter Rambach ◽  
Cornelia Lass-Florl ◽  
Manfred P. Dierich ◽  
Reinhard Wurzner
2021 ◽  
Vol 8 (4) ◽  
pp. 207-213
Author(s):  
Himanshi Narang ◽  
Amit Patil

The COVID-19 pandemic, which originated from Wuhan, China, has rapidly spread worldwide, including India. As India grappled with the second wave, COVID-triggered fungal infection has suddenly risen tremendously, raising a sense of panic in the country. The fungal infection in COVID-19 includes Mucormycosis and Aspergillosis, as common fungal infections primarily affecting rhino-orbital structures. Many research papers have published postmortem findings in autopsies conducted on COVID-19 decedents, thereby helping to understand this contagious disease's pathogenesis. But, with the arrival of COVID-triggered fungal infection, which is a crucial invasive disease responsible for fatality, very few research papers have commented on the postmortem findings of invasive fungal infections affecting the rhino-orbital and craniocerebral structures in COVID-19 deaths. Therefore, the role of invasive fungal infection due to COVID-19 illness must be established in the causation of deaths in COVID-19 patients. This review research deals with autopsy dissection techniques and possible postmortem findings of invasive fungal infections involving the nasal and paranasal sinuses and orbital structures in COVID-19 deaths. The findings of fungal infection affecting nasal and paranasal systems may not differ in live patients and in a deceased; however, it is essential that correct interpretation of the postmortem findings aided by pre-or post-autopsy investigations is necessary to establish the role of covid triggered fungal infection in such deaths.


2020 ◽  
Vol 6 (4) ◽  
pp. 209
Author(s):  
Livio Pagano ◽  
Chiara Cattaneo ◽  
Martina Quattrone ◽  
Margherita Oberti ◽  
Maria Mazzitelli ◽  
...  

The treatment of invasive fungal infections has deeply evolved in the last years with the inclusion of new antifungals, mainly new azoles (i.e., posaconazole, isavuconazole), to the therapeutic armamentarium. This review focuses on the role of isavuconazole for treating the most important invasive fungal infections both in animals and humans (hematological and non-hematological patients).


2011 ◽  
Vol 87 (4) ◽  
pp. 289-301 ◽  
Author(s):  
Oliver A. Cornely ◽  
Franco Aversa ◽  
Perry Cook ◽  
Brian Jones ◽  
Mauricette Michallet ◽  
...  

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