INTRODUCTION: The aim of this study was to investigate the important
factors affecting the COPD prognosis. MATERIAL AND METHODS: We included
160 hospitalized patients with COPD exacerbation in the study.
Hemoglobin-HB, hematocrit-HCT, leukocyte, red cell distribution width-
RDW, mean platelet volume, platelet distribution width, plateletcrit,
platelet, neutrophil / lymphocyte ratio, platelet / lymphocyte ratio,
eosinophil, uric acid, albumin, CRP, procalcitonin, arterial blood gases
(PO2, PCO2) pulmonary function test (FEV1, FVC), echocardiography
(ejection fraction-EF) GOLD stage, MMRC and BORG scales, Charlson
comorbidity index, body mass index-BMI, length of hospital stay were
examined on the first day of hospitalization. Admission to the hospital
with a new attack, hospitalization in the intensive care unit-ICU, and
mortality during the 6 months after discharge were evaluated. RESULTS:
High CRP and procalcitonin values were observed in the group with long
hospital stay. In mortality group, HB, HCT, BMI and PO2 values were
significantly lower than the group without mortality while age and GOLD
stage were higher. The age, BORG and MMRC scores, number of
exacerbations experienced in the previous 1 year, RDW, eosinophil count,
PCO2 were significantly higher in the ICU group than without ICU. HCT,
EF values were lower in the ICU group than without ICU. FEV1, FVC values
were significantly lower in follow-up attack group than without attack;
the duration of COPD and the number of experienced in the previous 1
year were high. CONCLUSION: It has been concluded that the scoring
combining selected biomarkers and other factors will be stronger in
determining the prognosis.
What are the Most Effective Factors in Determining Future Exacerbations, Morbidity Weight and Mortality In Patients Hospitalized wıth COPD Attack? A Prospective Study
