Hepatic iron accumulation is associated with disease progression and resistance to interferon/ribavirin combination therapy in chronic hepatitis C

2007 ◽  
Vol 22 (11) ◽  
pp. 1886-1893 ◽  
Author(s):  
Naoki Fujita ◽  
Ryosuke Sugimoto ◽  
Naohito Urawa ◽  
Jun Araki ◽  
Rumi Mifuji ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Hepatitis C ◽  
Combination Therapy ◽  
Disease Progression ◽  
Chronic Hepatitis C ◽  
Iron Accumulation ◽  
Hepatic Iron

Successful interferon therapy reverses enhanced hepatic iron accumulation and lipid peroxidation in chronic hepatitis C

2000 ◽  
Vol 95 (4) ◽  
pp. 1041-1050 ◽  
Author(s):  
Fujito Kageyama ◽  
Yoshimasa Kobayashi ◽  
Tsunehisa Kawasaki ◽  
Shinya Toyokuni ◽  
Koji Uchida ◽  
...  
Keyword(s):  
Lipid Peroxidation ◽  
Chronic Hepatitis ◽  
Hepatitis C ◽  
Chronic Hepatitis C ◽  
Interferon Therapy ◽  
Iron Accumulation ◽  
Hepatic Iron

scholarly journals The Role of Iron in the Pathophysiology and Treatment of Chronic Hepatitis C

2009 ◽  
Vol 23 (12) ◽  
pp. 822-828 ◽  
Author(s):  
Leslie Price ◽  
Kris V Kowdley
Keyword(s):  
Chronic Hepatitis ◽  
Hepatitis C ◽  
Disease Progression ◽  
Chronic Hepatitis C ◽  
Gene Mutations ◽  
Hepatic Iron ◽  
Hepatitis C Infection ◽  
Iron Depletion ◽  
Hepatic Iron Overload ◽  
Hemochromatosis Gene

Increased hepatic iron content may be observed in patients with chronic hepatitis C infection, and may contribute to disease severity. The presence of hemochromatosis gene mutations is associated with increased hepatic iron accumulation and may lead to accelerated disease progression. Hepatic iron depletion has been postulated to decrease the risk of hepatocellular carcinoma in patients with cirrhosis due to chronic hepatitis C. It is possible that iron depletion stabilizes or improves liver histology and slows disease progression in these individuals. The present article reviews the prevalence and risk factors for hepatic iron overload in chronic hepatitis C, with emphasis on the available data regarding the efficacy of iron depletion in the treatment of this common liver disease.

Hepatic iron accumulation may be associated with insulin resistance in patients with chronic hepatitis C

2007 ◽  
Vol 37 (11) ◽  
pp. 932-940 ◽  
Author(s):  
Yoshio Sumida ◽  
Kazuyuki Kanemasa ◽  
Kohei Fukumoto ◽  
Naohisa Yoshida ◽  
Kyoko Sakai
Keyword(s):  
Insulin Resistance ◽  
Chronic Hepatitis ◽  
Hepatitis C ◽  
Chronic Hepatitis C ◽  
Iron Accumulation ◽  
Hepatic Iron

Hepatic Iron Accumulation and Incidence of Hepatocellular Carcinoma in Patients with Chronic Hepatitis C

2003 ◽  
pp. 83-90
Author(s):  
Namiki Izumi ◽  
Yasuhiro Asahina ◽  
Osamu Noguchi ◽  
Masakatsu Uchihara ◽  
Sukenobu Kawamura ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Chronic Hepatitis ◽  
Hepatitis C ◽  
Chronic Hepatitis C ◽  
Iron Accumulation ◽  
Hepatic Iron
Sign in / Sign up

Export Citation Format

Share Document