Urinary Excretion and Clearance of Insulin in Diabetic and Normal Children and Adolescents

1993 ◽  
Vol 10 (8) ◽  
pp. 707-714
Author(s):  
P.E. Phillips ◽  
J.A. Edge ◽  
D.A. Harris ◽  
J.D.S. Kay ◽  
P. Tomlinson ◽  
...  
1964 ◽  
Vol 115 (1) ◽  
pp. 85-87 ◽  
Author(s):  
C. R. Jones ◽  
M. W. Bergman ◽  
P. J. Kittner ◽  
W. W. Pigman

2018 ◽  
Vol 41 (3) ◽  
pp. 287-296 ◽  
Author(s):  
Federico Canavese ◽  
Alain Dimeglio ◽  
François Bonnel ◽  
Marco Corradin ◽  
Bruno Pereira ◽  
...  

PEDIATRICS ◽  
1969 ◽  
Vol 43 (2) ◽  
pp. 183-191
Author(s):  
Robert F. Castle ◽  
Carol A. Hedden ◽  
N. Park Davis

Phonocardiograms were recorded in a population of normal children and adolescents (116 subjects) in order to evaluate variables which might affect splitting of the second heart sound. Tracings were recorded during normal respiration in supine and sitting positions. Position was the major variable affecting splitting. Eighty-five percent of this population exhibited greater variation in splitting when sitting than while supine. In the remainder of the subjects, the splitting variation was greater in the supine position. Heart rate, sex, age, height, and weight had little or no effect on the splitting pattern of the second sound; 15% of the subjects exhibited fixed splitting of the second sound in either, but not both, the supine and upright positions. This was defined as less than 10 msec variation in splitting during normal respiration. This observation indicates the necessity of assessing the second sound in both supine and upright positions before a judgment is made concerning the existence of an abnormal splitting pattern.


1979 ◽  
Vol 25 (7) ◽  
pp. 1325-1328 ◽  
Author(s):  
G Berglund ◽  
J Greter ◽  
S Lindstedt ◽  
G Steen ◽  
J Waldenström ◽  
...  

Abstract A two-year-old boy with a malignant tumor of the brain (medulloblastoma) excreted large amounts of thymine and uracil in his urine. The excretion was related to progress and regress of the disease, and reached a maximum of 3.0 mol of thymine per mole of creatinine and 2.6 mol of uracil per mole of creatinine. The excretion by 20 apparently normal children was less than 0.01 mol/mol of creatinine for each of the two pyrimidines. Three children with brain tumors, two with leukemias, and one with neuroblastoma were also studied; two of them had a moderate increase in urinary pyrimidine excretion, but only up to 0.07 mol/mol of creatinine. The activity of dihydrouracil dehydrogenase (NADP+) (EC 1.3.1.2) in cultured fibroblasts from the patient was somewhat lower than in control fibroblasts. The tumor was considered to be the likely cause of the increased excretion of pyrimidines, but an impaired degradation of pyrimidines in the liver could not be ruled out.


2009 ◽  
Vol 27 (6) ◽  
pp. 689-697 ◽  
Author(s):  
Oliver Fricke ◽  
Christof Land ◽  
Ralf Beccard ◽  
Oliver Semler ◽  
Angelika Stabrey ◽  
...  

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