Use of principal component analysis in the evaluation of adherence to statin treatment: a method to determine a potential target population for public health intervention

2010 ◽  
Vol 25 (4) ◽  
pp. 528-533 ◽  
Author(s):  
Philippe Latry ◽  
Karin Martin-Latry ◽  
Anne Labat ◽  
Mathieu Molimard ◽  
Claude Peter
2003 ◽  
Vol 1 (2-3) ◽  
pp. 151-156 ◽  
Author(s):  
R. L Sapra ◽  
S. K. Lal

AbstractWe suggest a diversity-dependent strategy, based on Principle Component Analysis, for selecting distinct accessions/parents for breeding from a soybean germplasm collection comprising of 463 lines, characterized and evaluated for 10 qualitative and eight quantitative traits. A sample size of six accessions included all the three states, namely low, medium and high of the individual quantitative traits, while a sample of 16–19 accessions included all the 60–64 distinct states of qualitative as well as quantitative traits. Under certain assumptions, the paper also develops an expression for estimating the size of a target population for capturing maximum variability in a sample three accessions.


Author(s):  
Devon K. Boyd ◽  
Matthew B. Parkinson

Digital Human Models (DHMs) are a tool that can be used to aid in determining dimensions for human-centered designs. DHMs have the ability to represent the anthropometric extremes of the population and help to determine which dimensions should be used to acquire a certain level of accommodation within a population. It is not possible to use current techniques for selecting manikins that represent a population, like principal component analysis (PCA), the application of design families, or percentiles due to these methods having a lower output accommodation levels than expected. The purpose of this research is to provide a multivariate analysis based on Pareto optimization. This method determines a pool of manikins representing the total target population when comparing up to three anthropometric dimensions within a database. This pool will act as boundary manikins for a given level of accommodation.


2019 ◽  
Vol 16 (1) ◽  
pp. 102-109
Author(s):  
A Oktavia ◽  
I Rina ◽  
V Agusta

Chernoff Face Method is a method used to represent multiple variable data in the form of a cartoon face with 20 specific facial features. In this study, we will show how the use of the Chernoff face method to see a portrait of public health in the city of Padang. Health indicators will be paired with specific facial features of Chernoff's face using Principal Component Analysis (PCA). The results of this study are expected to provide an overview of public health protection for each sub-district in Padang City and Padang City as a whole. Keywords : Chernoff Face Method, Health Indicators, Principal Component Ananlysis.


VASA ◽  
2012 ◽  
Vol 41 (5) ◽  
pp. 333-342 ◽  
Author(s):  
Kirchberger ◽  
Finger ◽  
Müller-Bühl

Background: The Intermittent Claudication Questionnaire (ICQ) is a short questionnaire for the assessment of health-related quality of life (HRQOL) in patients with intermittent claudication (IC). The objective of this study was to translate the ICQ into German and to investigate the psychometric properties of the German ICQ version in patients with IC. Patients and methods: The original English version was translated using a forward-backward method. The resulting German version was reviewed by the author of the original version and an experienced clinician. Finally, it was tested for clarity with 5 German patients with IC. A sample of 81 patients were administered the German ICQ. The sample consisted of 58.0 % male patients with a median age of 71 years and a median IC duration of 36 months. Test of feasibility included completeness of questionnaires, completion time, and ratings of clarity, length and relevance. Reliability was assessed through a retest in 13 patients at 14 days, and analysis of Cronbach’s alpha for internal consistency. Construct validity was investigated using principal component analysis. Concurrent validity was assessed by correlating the ICQ scores with the Short Form 36 Health Survey (SF-36) as well as clinical measures. Results: The ICQ was completely filled in by 73 subjects (90.1 %) with an average completion time of 6.3 minutes. Cronbach’s alpha coefficient reached 0.75. Intra-class correlation for test-retest reliability was r = 0.88. Principal component analysis resulted in a 3 factor solution. The first factor explained 51.5 of the total variation and all items had loadings of at least 0.65 on it. The ICQ was significantly associated with the SF-36 and treadmill-walking distances whereas no association was found for resting ABPI. Conclusions: The German version of the ICQ demonstrated good feasibility, satisfactory reliability and good validity. Responsiveness should be investigated in further validation studies.


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