scholarly journals Acute endotoxemia in rats induces down-regulation of V2 vasopressin receptors and aquaporin-2 content in the kidney medulla

2004 ◽  
Vol 65 (1) ◽  
pp. 54-62 ◽  
Author(s):  
Valery Grinevich ◽  
Mark A. Knepper ◽  
Joseph Verbalis ◽  
Ivan Reyes ◽  
Greti Aguilera
Keyword(s):  
Down Regulation ◽  
Kidney Medulla ◽  
Aquaporin 2 ◽  
Vasopressin Receptors ◽  
V2 Vasopressin Receptors

Down-regulation of V1a vasopressin receptors in the cerebellum after myocardial infarction

2011 ◽  
Vol 499 (2) ◽  
pp. 119-123 ◽  
Author(s):  
Elwira Milik ◽  
Ewa Szczepanska-Sadowska ◽  
Agnieszka Cudnoch-Jedrzejewska ◽  
Jakub Dobruch
Keyword(s):  
Myocardial Infarction ◽  
Down Regulation ◽  
Vasopressin Receptors

Disease-causing V2 Vasopressin Receptors are Retained in Different Compartments of the Early Secretory Pathway

Traffic ◽  
2004 ◽  
Vol 5 (12) ◽  
pp. 993-1005 ◽  
Author(s):  
Ricardo Hermosilla ◽  
Morad Oueslati ◽  
Ute Donalies ◽  
Eva Schönenberger ◽  
Eberhard Krause ◽  
...  
Keyword(s):  
Secretory Pathway ◽  
Early Secretory Pathway ◽  
Vasopressin Receptors ◽  
V2 Vasopressin Receptors

Activation of V2 vasopressin receptors induces recovery of motor function in patients with stroke, Parkinson’s disease and parkinsonism of different nature

2016 ◽  
Vol 14 (4) ◽  
pp. 52-60
Author(s):  
Svetlana G Belokoskova ◽  
Sergei G Tsikunov
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Clinical Trials ◽  
Motor Function ◽  
Movement Disorders ◽  
Effect Of Therapy ◽  
Vasopressin Receptors ◽  
V2 Vasopressin Receptors ◽  
Positive Effect ◽  
Recovery Of Motor Function

In clinical trials have studied effectiveness of agonist of V2 vasopressin receptors, 1-dezamino-8-D-arginine-vasopressin (DDAVP) in correction of movement disorders in patients with stroke, Parkinson’s disease and parkinsonism. Therapy received 15 patients with the stroke and 21 patients with the Parkinson’s disease and parkinsonism. Positive effect of therapy was observed in 67% of cases of stroke and in 73% cases of parkinsonian syndrome. After therapy of DDAVP movement disorders were regressed in patients with light hemiparesis after stroke. In patients with a tremor-rigid shape and akinetic-rigid form of the disease major movement disorders: tremor, rigidity, bradykinesia and hypokinesia were regressed. Except the disorders of movements affective and cognitive abnormalities were decreased. There was established that DDAVP effective in correction of disorders of voluntary and involuntary component of movements function in patients with the focal vascular and neurodegenerative diseases.

scholarly journals Lack of vasopressin receptors in liver, but not in kidney, of ob/ob mice

1983 ◽  
Vol 216 (2) ◽  
pp. 475-480 ◽  
Author(s):  
F Assimacopoulos-Jeannet ◽  
B Cantau ◽  
G van de Werve ◽  
S Jard ◽  
B Jeanrenaud
Keyword(s):  
Plasma Membrane ◽  
Adenylate Cyclase ◽  
Plasma Membranes ◽  
Metabolic Response ◽  
Isolated Hepatocytes ◽  
The Other ◽  
Kidney Medulla ◽  
Liver Plasma Membrane ◽  
Liver Plasma Membranes ◽  
Vasopressin Receptors

The activity of phosphorylase a was measured in isolated hepatocytes from fed lean and ob/ob mice after addition of vasopressin, angiotensin, phenylephrine and glucagon. The binding of these hormones to purified liver plasma membranes was also determined. In hepatocytes of ob/ob mice, no increase in phosphorylase a was measured after addition of vasopressin, whereas the other hormones promoted an increase in the activity of the enzyme. No specific vasopressin receptors could be measured on purified liver plasma membrane of ob/ob mice. A decrease in the number of receptors for angiotensin and glucagon, without modification of the affinity, was also observed. No restoration of the number of vasopressin receptors was observed in liver of ob/ob mice starved for 3 days or in younger (5-6 weeks) animals. Vasopressin receptors and vasopressin-stimulated adenylate cyclase, measured on purified kidney medulla membranes, were similar in both lean and ob/ob mice. The data indicate a selective lack of vasopressin receptors and metabolic response in liver of the ob/ob mouse.

scholarly journals Structural Implication for Receptor Oligomerization from Functional Reconstitution Studies of Mutant V2 Vasopressin Receptors

2000 ◽  
Vol 275 (4) ◽  
pp. 2381-2389 ◽  
Author(s):  
Angela Schulz ◽  
Robert Grosse ◽  
Günter Schultz ◽  
Thomas Gudermann ◽  
Torsten Schöneberg
Keyword(s):  
Receptor Oligomerization ◽  
Vasopressin Receptors ◽  
V2 Vasopressin Receptors
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