Cutaneous Vasculitis as the Initial Manifestation of Crohn's Disease in a Pediatric Patient

1998 ◽  
Vol 93 (6) ◽  
pp. 1014-1014 ◽  
Author(s):  
Marsha H. Kay ◽  
Robert Wyllie
2020 ◽  
Vol 158 (3) ◽  
pp. S101-S102
Author(s):  
Julia Schuchard ◽  
Michael Kappelman ◽  
Andrew Grossman ◽  
Jennifer Clegg ◽  
Christopher Forrest

2012 ◽  
Vol 3 (3) ◽  
pp. 201-205 ◽  
Author(s):  
James Callaghan ◽  
Sarah Brown ◽  
Tim Battcock ◽  
Sally Parry ◽  
Jonathon Snook

2009 ◽  
Vol 150 (40) ◽  
pp. 1858-1860 ◽  
Author(s):  
Gábor Veres ◽  
Réka Putz ◽  
Dolóresz Szabó ◽  
Kriszta Molnár ◽  
Hedvig Bodánszky ◽  
...  

Hagyományos kezelésre refrakter, fistulás Crohn-betegek kezelésében a chimer antitumornekrózis-faktor-alfa- (infliximab-) terápia igen hatékony, bár a betegek egy részében infliximabrezisztencia alakulhat ki. A szerzők egy infliximabrezisztens, 12 éves Crohn-beteg fiú esetét ismertetik, akinek luminális gyulladása mellett 3 aktív perianalis fistulája is volt. Teljesen humanizált antitumornekrózis-faktor-alfa- (adalimumab-) kezelést követően a 10. héten a fistulák bezáródtak, a korábbi magas aktivitási index normalizálódott. Validált életminőségi mutatók szintén szignifikánsan javultak. Az eset alapján infliximabrezisztens Crohn-beteg gyermeknél az adalimumabterápia sikerrel alkalmazható.


2010 ◽  
Vol 26 (11) ◽  
pp. 1125-1128 ◽  
Author(s):  
Andrea Bischoff ◽  
Anita Gupta ◽  
Sharon D’Mello ◽  
Adam Mezoff ◽  
Daniel Podberesky ◽  
...  

2020 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Elana B. Mitchel ◽  
Adam Paul ◽  
Alexander El-Ali ◽  
Pi-Yu Cheng ◽  
Lindsey G. Albenberg

2012 ◽  
Vol 2012 ◽  
pp. 1-3 ◽  
Author(s):  
Sharon McGreal ◽  
Rupert Sayers ◽  
Peter Wurm ◽  
Kevin West

Pyogenic liver abscess (PLA) is a rare extraintestinal complication of Crohn’s disease (CD), and the clinical and laboratory findings may emulate the reactivation of CD, therefore, delaying diagnosis. In this paper the patient presented with PLA as the initial manifestation of CD and experienced severe disease. The finding of PLA was established by computed tomography and initial treatment involved percutaneous drainage and antibiotics. The diagnosis of CD was made after colonoscopy and histological investigations.


2015 ◽  
Vol 2015 ◽  
pp. 1-7 ◽  
Author(s):  
Victoria L. Woo

Crohn’s disease (CD) is an inflammatory disorder of the gastrointestinal tract that is likely caused by an inappropriate mucosal inflammatory response to intestinal bacteria in a genetically predisposed host. The lesions of CD can involve any region of the GI tract as well as extraintestinal sites such as the skin, joints, and eyes. The most common presenting symptoms are abdominal pain and prolonged diarrhea associated with fevers, fatigue, and malaise. Delayed growth and failure to thrive may also be observed in pediatric patients. Oral manifestations of CD are known as oral CD and may precede GI involvement, thus serving as early markers of this condition. We describe a 6-year-old male who presented with oral lesions as his initial manifestation of disease and review the current literature pertaining to oral CD.


2002 ◽  
Vol 14 (8) ◽  
pp. 873-876 ◽  
Author(s):  
C. Girlich ◽  
T. Bogenrieder ◽  
K.-D. Palitzsch ◽  
J. Schölmerich ◽  
G. Lock

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