scholarly journals Mesenchymal stem cells and cardiac repair

2008 ◽  
Vol 12 (5b) ◽  
pp. 1795-1810 ◽  
Author(s):  
Catharina Nesselmann ◽  
Nan Ma ◽  
Karen Bieback ◽  
Wolfgang Wagner ◽  
Anthony Ho ◽  
...  
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Cardiac Repair

scholarly journals INCREASED POTENCY OF CARDIAC STEM CELLS COMPARED TO BONE MARROW MESENCHYMAL STEM CELLS IN CARDIAC REPAIR

2011 ◽  
Vol 57 (14) ◽  
pp. E1014
Author(s):  
Behzad Nasehi Oskouei ◽  
Guillaume Lamirault ◽  
Chacko Joseph ◽  
Stephanie Landa ◽  
Marc Dauer ◽  
...  
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Mesenchymal Stem Cells ◽  
Cardiac Repair ◽  
Cardiac Stem Cells ◽  
Marrow Mesenchymal Stem Cells

Allogeneic Mesenchymal Stem Cells in Cellular Cardiomyoplasty: Mechanisms of Cardiac Repair

Circulation ◽  
2008 ◽  
Vol 118 (suppl_18) ◽  
Author(s):  
Konstantinos Hatzistergos
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Cardiac Repair ◽  
Cellular Cardiomyoplasty

Abstract 486 Konstantinos E. Hatzistergos, Henry Quevedo, Behzad N. Oskouei, Qinghua Hu, Ramesh Mazhari, Juan P. Zambrano, David Valdes, Gary S. Feigenbaum, Jose R. Rodriguez, Irene S. Margitich, Jeffrey M. Zimmet, Univ of Miami, Miami, FL; Concepción Revilla, INIA, Madrid, Spain; Alan W. Heldman, Ian McNiece, Joshua M. Hare, Univ of Miami, Miami, FL Konstantinos Hatzistergos, 2008 Finalist and Presenting Author

Mesenchymal Stem Cells for Cardiac Repair: Preclinical Models of Disease

2014 ◽  
pp. 1-19
Author(s):  
Manuel Mazo ◽  
Miriam Araña ◽  
Beatriz Pelacho ◽  
Felipe Prosper
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Cardiac Repair ◽  
Preclinical Models ◽  
Models Of Disease

scholarly journals Cardiac Repair With a Novel Population of Mesenchymal Stem Cells Resident in the Human Heart

Stem Cells ◽  
2015 ◽  
Vol 33 (10) ◽  
pp. 3100-3113 ◽  
Author(s):  
Yuan Zhang ◽  
Priyadharshini Sivakumaran ◽  
Andrew E. Newcomb ◽  
Damián Hernandez ◽  
Nicole Harris ◽  
...  
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Human Heart ◽  
Cardiac Repair

HYPOXIA MODULATES HUMAN PLACENTA-DERIVED MESENCHYMAL STEM CELLS MIGRATION IN VITRO FOR CARDIAC REPAIR

2016 ◽  
Vol 32 (10) ◽  
pp. S276
Author(s):  
L. Li ◽  
P. Jaiswal ◽  
R. Jurakhan ◽  
K. Selvasandran ◽  
K. Ridwan ◽  
...  
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Human Placenta ◽  
Cardiac Repair

Reduced graphene oxide facilitates biocompatibility of alginate for cardiac repair

2020 ◽  
Vol 35 (4-5) ◽  
pp. 363-377
Author(s):  
Negar Karimi Hajishoreh ◽  
Nafiseh Baheiraei ◽  
Nasim Naderi ◽  
Mojdeh Salehnia
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Tissue Culture ◽  
Mesenchymal Stem Cells ◽  
Graphene Oxide ◽  
Physicochemical Properties ◽  
Reduced Graphene Oxide ◽  
Cardiac Repair ◽  
Reduced Graphene ◽  
Tissue Culture Plate

The benefits of combined cell/material therapy appear promising for myocardial infarction treatment. The safety of alginate, along with its excellent biocompatibility and biodegradability, has been extensively investigated for cardiac tissue engineering. Among graphene-based nanomaterials, reduced graphene oxide has been considered as a promising candidate for cardiac treatment due to its unique physicochemical properties. In this study, the reduced graphene oxide incorporation effect within alginate hydrogels was investigated for cardiac repair application. Reduced graphene oxide reinforced alginate properties, resulting in an increase in gel stiffness. The cytocompatibility of the hydrogels prepared with human bone marrow–derived mesenchymal stem cells was assessed by the 3-(4,5dimethylthiazol-2-yl)-2,5-diphenyltetrazoliumbromide) assay. Following reduced graphene oxide addition, alginate-reduced graphene oxide retained significantly higher cell viability compared to that of alginate and cells cultured on tissue culture plates. Acridine orange/propidium iodide staining was also used to identify both viable and necrotic human bone marrow–derived mesenchymal stem cells within the prepared hydrogels. After a 72-h culture, the percentage of viable cells was twice as much as those cultured on either alginate or tissue culture plate, reaching approximately 80%. Quantitative reverse transcription polymerase chain reaction analysis was performed to assess gene expression of neonatal rat cardiac cells encapsulated on hydrogels for TrpT-2, Conx43, and Actn4 after 7 days. The expression of all genes in alginate-reduced graphene oxide increased significantly compared to that in alginate or tissue culture plate. The results obtained confirmed that the presence of reduced graphene oxide, as an electro-active moiety within alginate, could tune the physicochemical properties of this material, providing a desirable electroactive hydrogel for stem cell therapy in patients with ischemic heart disease.

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